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EIF5B eukaryotic translation initiation factor 5B [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 714129, updated on 17-Aug-2024

Summary

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Official Symbol
EIF5Bprovided by VGNC
Official Full Name
eukaryotic translation initiation factor 5Bprovided by VGNC
Primary source
VGNC:VGNC:72148
See related
Ensembl:ENSMMUG00000018946
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See EIF5B in Genome Data Viewer
Location:
chromosome: 13
Exon count:
24
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 13 NC_041766.1 (3157503..3220969)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 13 NC_027905.1 (94605124..94668776)

Chromosome 13 - NC_041766.1Genomic Context describing neighboring genes Neighboring gene lysozyme g1 Neighboring gene thioredoxin domain containing 9 Neighboring gene REV1 DNA directed polymerase Neighboring gene 60S ribosomal protein L36a-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables translation initiation factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
eukaryotic translation initiation factor 5B
NP_001248539.1
XP_014968397.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001261610.1 → NP_001248539.1  eukaryotic translation initiation factor 5B

    See identical proteins and their annotated locations for NP_001248539.1

    Status: PROVISIONAL

    Source sequence(s)
    JV048809
    UniProtKB/TrEMBL
    A0A1D5Q0Z8, A0A5F7ZUP7
    Related
    ENSMMUP00000068883.1, ENSMMUT00000080381.1
    Conserved Domains (6) summary
    cd01887
    Location:633 → 846
    IF2_eIF5B; Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family
    PRK04004
    Location:628 → 1203
    PRK04004; translation initiation factor IF-2; Validated
    pfam08070
    Location:110 → 171
    DTHCT; DTHCT (NUC029) region
    pfam11987
    Location:967 → 1068
    IF-2; Translation-initiation factor 2
    cd03703
    Location:856 → 966
    aeIF5B_II; Domain II of archaeal and eukaryotic Initiation Factor 5
    cd16266
    Location:1093 → 1187
    IF2_aeIF5B_IV; Domain IV of prokaryotic Initiation Factor 2 and archaeal and eukaryotic Initiation Factor 5

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041766.1 Reference Mmul_10 Primary Assembly

    Range
    3157503..3220969
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015112911.2 → XP_014968397.1  eukaryotic translation initiation factor 5B isoform X1

    UniProtKB/TrEMBL
    A0A1D5Q0Z8
    Conserved Domains (6) summary
    cd01887
    Location:632 → 845
    IF2_eIF5B; Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family
    PRK04004
    Location:627 → 1202
    PRK04004; translation initiation factor IF-2; Validated
    pfam08070
    Location:110 → 171
    DTHCT; DTHCT (NUC029) region
    pfam11987
    Location:966 → 1067
    IF-2; Translation-initiation factor 2
    cd03703
    Location:855 → 965
    aeIF5B_II; Domain II of archaeal and eukaryotic Initiation Factor 5
    cd16266
    Location:1092 → 1186
    IF2_aeIF5B_IV; Domain IV of prokaryotic Initiation Factor 2 and archaeal and eukaryotic Initiation Factor 5
Nucleotide Protein
Heading Accession and Version

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