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BCAR1 BCAR1 scaffold protein, Cas family member [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 713965, updated on 17-Aug-2024

Summary

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Official Symbol
BCAR1provided by VGNC
Official Full Name
BCAR1 scaffold protein, Cas family memberprovided by VGNC
Primary source
VGNC:VGNC:70234
See related
Ensembl:ENSMMUG00000002630
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See BCAR1 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
11
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 20 NC_041773.1 (62206402..62251543, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 20 NC_027912.1 (59517532..59556703, complement)

Chromosome 20 - NC_041773.1Genomic Context describing neighboring genes Neighboring gene chymotrypsinogen B2 Neighboring gene chymotrypsinogen B Neighboring gene U6 spliceosomal RNA Neighboring gene craniofacial development protein 1 Neighboring gene uncharacterized LOC114674408

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
breast cancer anti-estrogen resistance protein 1
Names
BCAR1, Cas family scaffold protein
BCAR1, Cas family scaffolding protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041773.1 Reference Mmul_10 Primary Assembly

    Range
    62206402..62251543 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015126628.2 → XP_014982114.1  breast cancer anti-estrogen resistance protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A1D5R6V3, F7H778, I0FWM3
    Related
    ENSMMUP00000056041.2, ENSMMUT00000075826.2
    Conserved Domains (3) summary
    cd12001
    Location:23 → 89
    SH3_BCAR1; Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1
    pfam12026
    Location:673 → 882
    DUF3513; Domain of unknown function (DUF3513)
    cl07433
    Location:472 → 628
    Serine_rich_CAS; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding proteins; a protein interaction module

  2. XM_015126630.2 → XP_014982116.1  breast cancer anti-estrogen resistance protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A5F8AK84, H9G269
    Related
    ENSMMUP00000077426.1, ENSMMUT00000081547.1
    Conserved Domains (3) summary
    cd12001
    Location:5 → 71
    SH3_BCAR1; Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1
    pfam12026
    Location:655 → 864
    DUF3513; Domain of unknown function (DUF3513)
    cl07433
    Location:454 → 610
    Serine_rich_CAS; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding proteins; a protein interaction module

  3. XM_028841205.1 → XP_028697038.1  breast cancer anti-estrogen resistance protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A1D5QBS0, F7H778
    Conserved Domains (4) summary
    cd12001
    Location:15 → 81
    SH3_BCAR1; Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1
    PHA03247
    Location:93 → 407
    PHA03247; large tegument protein UL36; Provisional
    cl07433
    Location:464 → 620
    Serine_rich_CAS; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding proteins; a protein interaction module
    pfam12026
    Location:665 → 874
    DUF3513; Domain of unknown function (DUF3513)

  4. XM_028841207.1 → XP_028697040.1  breast cancer anti-estrogen resistance protein 1 isoform X5

    UniProtKB/TrEMBL
    A0A1D5QBS0, A0A1D5QE98, F7H778
    Related
    ENSMMUP00000046367.2, ENSMMUT00000060118.2
    Conserved Domains (4) summary
    PHA03247
    Location:54 → 368
    PHA03247; large tegument protein UL36; Provisional
    cl07433
    Location:425 → 581
    Serine_rich_CAS; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding proteins; a protein interaction module
    pfam12026
    Location:626 → 835
    DUF3513; Domain of unknown function (DUF3513)
    cl17036
    Location:1 → 41
    SH3; Src Homology 3 domain superfamily

  5. XM_015126631.2 → XP_014982117.1  breast cancer anti-estrogen resistance protein 1 isoform X6

    UniProtKB/TrEMBL
    G7NR24
    Conserved Domains (3) summary
    cd12001
    Location:51 → 117
    SH3_BCAR1; Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1
    pfam12026
    Location:701 → 910
    DUF3513; Domain of unknown function (DUF3513)
    cl07433
    Location:500 → 656
    Serine_rich_CAS; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding proteins; a protein interaction module

  6. XM_015126629.2 → XP_014982115.1  breast cancer anti-estrogen resistance protein 1 isoform X3

    UniProtKB/TrEMBL
    H9G270, I0FWM4
    Related
    ENSMMUP00000067662.1, ENSMMUT00000099657.1
    Conserved Domains (3) summary
    cd12001
    Location:4 → 71
    SH3_BCAR1; Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1
    pfam12026
    Location:655 → 864
    DUF3513; Domain of unknown function (DUF3513)
    cl07433
    Location:454 → 610
    Serine_rich_CAS; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding proteins; a protein interaction module
Nucleotide Protein
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