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HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 713541, updated on 17-Aug-2024

Summary

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Official Symbol
HMGCS2provided by VGNC
Official Full Name
3-hydroxy-3-methylglutaryl-CoA synthase 2provided by VGNC
Primary source
VGNC:VGNC:73486
Locus tag
EGK_01163
See related
Ensembl:ENSMMUG00000023097
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See HMGCS2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
10
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (104524217..104545746)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (120932350..120953628, complement)

Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114678101 Neighboring gene regenerating family member 4 Neighboring gene phosphoglycerate dehydrogenase Neighboring gene uncharacterized LOC107000199

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydroxymethylglutaryl-CoA synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in acetyl-CoA metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in farnesyl diphosphate biosynthetic process, mevalonate pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hydroxymethylglutaryl-CoA synthase, mitochondrial
Names
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)
XP_001114146.2
XP_015004875.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041754.1 Reference Mmul_10 Primary Assembly

    Range
    104524217..104545746
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015149389.2 → XP_015004875.2  hydroxymethylglutaryl-CoA synthase, mitochondrial

    UniProtKB/TrEMBL
    F7DRJ3, I2CVM8
    Conserved Domains (1) summary
    TIGR01833
    Location:50 → 506
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade

  2. XM_001114146.4 → XP_001114146.2  hydroxymethylglutaryl-CoA synthase, mitochondrial

    UniProtKB/TrEMBL
    F7DRJ3, I2CVM8
    Related
    ENSMMUP00000030407.4, ENSMMUT00000032496.4
    Conserved Domains (1) summary
    TIGR01833
    Location:50 → 506
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade
Nucleotide Protein
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Research Materials