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MAPKAPK5 MAPK activated protein kinase 5 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 713521, updated on 18-Sep-2024

Summary

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Official Symbol
MAPKAPK5provided by VGNC
Official Full Name
MAPK activated protein kinase 5provided by VGNC
Primary source
VGNC:VGNC:74655
Locus tag
EGK_04198
See related
Ensembl:ENSMMUG00000022353
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See MAPKAPK5 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
14
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (111513795..111565418)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (111935803..111964712, complement)

Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene aldehyde dehydrogenase 2 family member Neighboring gene endogenous retrovirus group K member 6 Env polyprotein-like Neighboring gene endogenous retrovirus group K member 25 Env polyprotein-like Neighboring gene putative uncharacterized protein encoded by MAPKAPK5-AS1 Neighboring gene uncharacterized LOC106996134 Neighboring gene a disintegrin and metalloproteinase domain 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium-dependent protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium/calmodulin-dependent protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mitogen-activated protein kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Ras protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of TOR signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-serine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein autophosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
MAP kinase-activated protein kinase 5
Names
mitogen-activated protein kinase-activated protein kinase 5
NP_001244779.1
XP_028684812.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001257850.1 → NP_001244779.1  MAP kinase-activated protein kinase 5

    See identical proteins and their annotated locations for NP_001244779.1

    Status: PROVISIONAL

    Source sequence(s)
    JU336852
    UniProtKB/TrEMBL
    A0A8J8XYT5, F6ZBS3, G7N5I2, H9G146
    Related
    ENSMMUP00000029425.4, ENSMMUT00000031447.4
    Conserved Domains (1) summary
    cd14171
    Location:15 → 304
    STKc_MAPKAPK5; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase-activated protein kinase 5

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041764.1 Reference Mmul_10 Primary Assembly

    Range
    111513795..111565418
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028828979.1 → XP_028684812.1  MAP kinase-activated protein kinase 5 isoform X1

    UniProtKB/TrEMBL
    A0A1D5Q845, F6ZBS3, H9ZEN3
    Related
    ENSMMUP00000044212.2, ENSMMUT00000075703.2
    Conserved Domains (1) summary
    cd14171
    Location:15 → 304
    STKc_MAPKAPK5; Catalytic domain of the Serine/Threonine kinase, Mitogen-activated protein kinase-activated protein kinase 5
Nucleotide Protein
Heading Accession and Version

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