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DGKZ diacylglycerol kinase zeta [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 713198, updated on 18-Sep-2024

Summary

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Official Symbol
DGKZprovided by VGNC
Official Full Name
diacylglycerol kinase zetaprovided by VGNC
Primary source
VGNC:VGNC:71789
See related
Ensembl:ENSMMUG00000021446
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See DGKZ in Genome Data Viewer
Location:
chromosome: 14
Exon count:
35
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (19388739..19437554, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (19666294..19715484, complement)

Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene autophagy and beclin 1 regulator 1 Neighboring gene cholinergic receptor muscarinic 4 Neighboring gene midkine Neighboring gene cAMP responsive element binding protein 3 like 1 Neighboring gene U2 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP-dependent diacylglycerol kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in diacylglycerol metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of synaptic transmission, glutamatergic IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
diacylglycerol kinase zeta
Names
diacylglycerol kinase, zeta 104kDa
XP_014969868.1
XP_014969870.1
XP_014969871.1
XP_014969872.1
XP_014969873.1
XP_014969874.1
XP_014969875.1
XP_014969876.1
XP_014969877.2
XP_014969878.2
XP_028689311.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041767.1 Reference Mmul_10 Primary Assembly

    Range
    19388739..19437554 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015114388.2 → XP_014969874.1  diacylglycerol kinase zeta isoform X8

    UniProtKB/TrEMBL
    A0A1D5QBS3
    Related
    ENSMMUP00000045492.2, ENSMMUT00000066938.2
    Conserved Domains (6) summary
    smart00045
    Location:463 → 620
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:314 → 435
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    sd00045
    Location:811 → 837
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:811 → 905
    Ank_2; Ankyrin repeats (3 copies)
    cd20849
    Location:105 → 177
    C1_DGKzeta_rpt1; first protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase zeta (DAG kinase zeta) and similar proteins
    cd20895
    Location:187 → 261
    C1_DGKzeta_rpt2; second protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase zeta (DAG kinase zeta) and similar proteins

  2. XM_015114387.2 → XP_014969873.1  diacylglycerol kinase zeta isoform X7

    UniProtKB/TrEMBL
    A0A1D5QBS3, A0A1D5QV26, I2CU98
    Related
    ENSMMUP00000051906.2, ENSMMUT00000072195.2
    Conserved Domains (7) summary
    smart00045
    Location:464 → 621
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:315 → 436
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    COG1597
    Location:311 → 634
    LCB5; Diacylglycerol kinase family enzyme [Lipid transport and metabolism, General function prediction only]
    cd00204
    Location:812 → 928
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:812 → 906
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:812 → 838
    ANK; ANK repeat [structural motif]
    cl00040
    Location:190 → 249
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...

  3. XM_015114392.2 → XP_014969878.2  diacylglycerol kinase zeta isoform X6

    UniProtKB/TrEMBL
    A0A1D5RBV3
    Conserved Domains (5) summary
    smart00045
    Location:489 → 646
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:340 → 461
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    sd00045
    Location:837 → 863
    ANK; ANK repeat [structural motif]
    pfam00130
    Location:215 → 266
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam12796
    Location:837 → 931
    Ank_2; Ankyrin repeats (3 copies)

  4. XM_015114391.2 → XP_014969877.2  diacylglycerol kinase zeta isoform X5

    UniProtKB/TrEMBL
    A0A1D5RBV3
    Related
    ENSMMUP00000057795.2, ENSMMUT00000070002.2
    Conserved Domains (5) summary
    smart00045
    Location:490 → 647
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:341 → 462
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    sd00045
    Location:838 → 864
    ANK; ANK repeat [structural motif]
    pfam00130
    Location:216 → 267
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam12796
    Location:838 → 932
    Ank_2; Ankyrin repeats (3 copies)

  5. XM_028833478.1 → XP_028689311.1  diacylglycerol kinase zeta isoform X11

    UniProtKB/TrEMBL
    F7EAP8
    Conserved Domains (5) summary
    smart00045
    Location:326 → 483
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:177 → 298
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    sd00045
    Location:674 → 700
    ANK; ANK repeat [structural motif]
    pfam00130
    Location:52 → 103
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam12796
    Location:674 → 768
    Ank_2; Ankyrin repeats (3 copies)

  6. XM_015114390.2 → XP_014969876.1  diacylglycerol kinase zeta isoform X10

    UniProtKB/TrEMBL
    F7EAP8
    Conserved Domains (6) summary
    smart00045
    Location:446 → 603
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:297 → 418
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    sd00045
    Location:794 → 820
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:794 → 888
    Ank_2; Ankyrin repeats (3 copies)
    cd20849
    Location:88 → 160
    C1_DGKzeta_rpt1; first protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase zeta (DAG kinase zeta) and similar proteins
    cd20895
    Location:170 → 244
    C1_DGKzeta_rpt2; second protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase zeta (DAG kinase zeta) and similar proteins

  7. XM_015114389.2 → XP_014969875.1  diacylglycerol kinase zeta isoform X9

    UniProtKB/TrEMBL
    F7EAP8, H9G116
    Related
    ENSMMUP00000066461.1, ENSMMUT00000108549.1
    Conserved Domains (6) summary
    smart00045
    Location:447 → 604
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:298 → 419
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    sd00045
    Location:795 → 821
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:795 → 889
    Ank_2; Ankyrin repeats (3 copies)
    cd20849
    Location:88 → 161
    C1_DGKzeta_rpt1; first protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase zeta (DAG kinase zeta) and similar proteins
    cd20895
    Location:171 → 245
    C1_DGKzeta_rpt2; second protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase zeta (DAG kinase zeta) and similar proteins

  8. XM_015114386.2 → XP_014969872.1  diacylglycerol kinase zeta isoform X4

    UniProtKB/TrEMBL
    A0A1D5R745, H9ZEK6
    Related
    ENSMMUP00000056133.2, ENSMMUT00000063742.2
    Conserved Domains (5) summary
    smart00045
    Location:636 → 793
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:487 → 608
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    sd00045
    Location:984 → 1010
    ANK; ANK repeat [structural motif]
    pfam00130
    Location:362 → 413
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam12796
    Location:984 → 1078
    Ank_2; Ankyrin repeats (3 copies)

  9. XM_015114385.2 → XP_014969871.1  diacylglycerol kinase zeta isoform X3

    UniProtKB/TrEMBL
    H9ZEK6, I2CUS8
    Related
    ENSMMUP00000048845.2, ENSMMUT00000065371.2
    Conserved Domains (7) summary
    smart00045
    Location:637 → 794
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:488 → 609
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    COG1597
    Location:484 → 807
    LCB5; Diacylglycerol kinase family enzyme [Lipid transport and metabolism, General function prediction only]
    cd00204
    Location:985 → 1101
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00130
    Location:363 → 422
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam12796
    Location:985 → 1079
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:985 → 1011
    ANK; ANK repeat [structural motif]

  10. XM_015114384.2 → XP_014969870.1  diacylglycerol kinase zeta isoform X2

    UniProtKB/TrEMBL
    H9ZEK6
    Conserved Domains (7) summary
    smart00045
    Location:689 → 846
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:540 → 661
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    COG1597
    Location:536 → 859
    LCB5; Diacylglycerol kinase family enzyme [Lipid transport and metabolism, General function prediction only]
    cd00204
    Location:1037 → 1153
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00130
    Location:415 → 474
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam12796
    Location:1037 → 1131
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:1037 → 1063
    ANK; ANK repeat [structural motif]

  11. XM_015114382.2 → XP_014969868.1  diacylglycerol kinase zeta isoform X1

    UniProtKB/TrEMBL
    H9ZEK6
    Conserved Domains (7) summary
    smart00045
    Location:690 → 847
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:541 → 662
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    COG1597
    Location:537 → 860
    LCB5; Diacylglycerol kinase family enzyme [Lipid transport and metabolism, General function prediction only]
    cd00204
    Location:1038 → 1154
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00130
    Location:416 → 475
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam12796
    Location:1038 → 1132
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:1038 → 1064
    ANK; ANK repeat [structural motif]

RNA

  1. XR_003722543.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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