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KCNH1 potassium voltage-gated channel subfamily H member 1 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 712190, updated on 20-Oct-2024

Summary

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Official Symbol
KCNH1provided by VGNC
Official Full Name
potassium voltage-gated channel subfamily H member 1provided by VGNC
Primary source
VGNC:VGNC:97779
Locus tag
EGK_01688
See related
Ensembl:ENSMMUG00000016102
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See KCNH1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
11
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (68171234..68624281, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (155393545..155845185)

Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene ribonuclease H1 pseudogene Neighboring gene U5 spliceosomal RNA Neighboring gene hedgehog acyltransferase Neighboring gene importin-7 pseudogene Neighboring gene 40S ribosomal protein S25 pseudogene Neighboring gene REST corepressor 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables delayed rectifier potassium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in potassium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of membrane potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
voltage-gated delayed rectifier potassium channel KCNH1; potassium voltage-gated channel subfamily H member 1
Names
potassium voltage-gated channel, subfamily H (eag-related), member 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001267017.1 → NP_001253946.1  voltage-gated delayed rectifier potassium channel KCNH1

    See identical proteins and their annotated locations for NP_001253946.1

    Status: PROVISIONAL

    Source sequence(s)
    JU471132
    UniProtKB/TrEMBL
    A0A5K1UTZ2
    Related
    ENSMMUP00000064286.1, ENSMMUT00000086708.1
    Conserved Domains (3) summary
    pfam13426
    Location:41 → 135
    PAS_9; PAS domain
    cl26073
    Location:220 → 620
    Ank_2; Ankyrin repeats (3 copies)
    cl28240
    Location:581 → 685
    Crp; cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041754.1 Reference Mmul_10 Primary Assembly

    Range
    68171234..68624281 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015116791.2 → XP_014972277.1  potassium voltage-gated channel subfamily H member 1 isoform X1

    UniProtKB/TrEMBL
    A0A8J8Y8B7, G7MEN1, H9YW69
    Conserved Domains (6) summary
    COG0664
    Location:575 → 720
    Crp; cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]
    cd00038
    Location:581 → 691
    CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
    cd00130
    Location:39 → 133
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam00520
    Location:235 → 510
    Ion_trans; Ion transport protein
    pfam07885
    Location:450 → 504
    Ion_trans_2; Ion channel
    pfam13426
    Location:39 → 135
    PAS_9; PAS domain
Nucleotide Protein
Heading Accession and Version

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