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RNF146 ring finger protein 146 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 712152, updated on 17-Aug-2024

Summary

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Official Symbol
RNF146provided by VGNC
Official Full Name
ring finger protein 146provided by VGNC
Primary source
VGNC:VGNC:76798
Locus tag
EGK_15370
See related
Ensembl:ENSMMUG00000015354
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See RNF146 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
5
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (30808474..30830192)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (140329920..140351828, complement)

Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene R-spondin 3 Neighboring gene uncharacterized LOC106998157 Neighboring gene uncharacterized LOC114677484 Neighboring gene ethylmalonyl-CoA decarboxylase 1 Neighboring gene 14-3-3 protein zeta/delta pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables poly-ADP-D-ribose binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase RNF146
NP_001253516.1
XP_014992779.1
XP_014992780.1
XP_014992782.1
XP_014992783.1
XP_014992784.1
XP_028702624.1
XP_028702625.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001266587.1 → NP_001253516.1  E3 ubiquitin-protein ligase RNF146

    See identical proteins and their annotated locations for NP_001253516.1

    Status: PROVISIONAL

    Source sequence(s)
    JV048356
    UniProtKB/TrEMBL
    A0A8J8XK00, F7GUD1, G7MQF3
    Conserved Domains (2) summary
    smart00678
    Location:103 → 175
    WWE; Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis
    cd16546
    Location:35 → 74
    RING-HC_RNF146; RING finger, HC subclass, found in RING finger protein 146 (RNF146) and similar proteins

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041757.1 Reference Mmul_10 Primary Assembly

    Range
    30808474..30830192
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015137298.2 → XP_014992784.1  E3 ubiquitin-protein ligase RNF146 isoform X2

    UniProtKB/TrEMBL
    A0A8J8XK00, F7GUD1, G7MQF3
    Related
    ENSMMUP00000079705.1, ENSMMUT00000096822.1
    Conserved Domains (2) summary
    smart00678
    Location:103 → 175
    WWE; Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis
    cd16546
    Location:35 → 74
    RING-HC_RNF146; RING finger, HC subclass, found in RING finger protein 146 (RNF146) and similar proteins

  2. XM_015137296.2 → XP_014992782.1  E3 ubiquitin-protein ligase RNF146 isoform X2

    UniProtKB/TrEMBL
    A0A8J8XK00, F7GUD1, G7MQF3
    Related
    ENSMMUP00000033088.1, ENSMMUT00000040018.3
    Conserved Domains (2) summary
    smart00678
    Location:103 → 175
    WWE; Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis
    cd16546
    Location:35 → 74
    RING-HC_RNF146; RING finger, HC subclass, found in RING finger protein 146 (RNF146) and similar proteins

  3. XM_015137293.2 → XP_014992779.1  E3 ubiquitin-protein ligase RNF146 isoform X1

    UniProtKB/TrEMBL
    F6SP59
    Related
    ENSMMUP00000081157.1, ENSMMUT00000083246.1
    Conserved Domains (2) summary
    smart00678
    Location:104 → 176
    WWE; Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis
    cd16546
    Location:36 → 75
    RING-HC_RNF146; RING finger, HC subclass, found in RING finger protein 146 (RNF146) and similar proteins

  4. XM_015137297.2 → XP_014992783.1  E3 ubiquitin-protein ligase RNF146 isoform X2

    UniProtKB/TrEMBL
    A0A8J8XK00, F7GUD1, G7MQF3
    Related
    ENSMMUP00000068244.1, ENSMMUT00000105506.1
    Conserved Domains (2) summary
    smart00678
    Location:103 → 175
    WWE; Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis
    cd16546
    Location:35 → 74
    RING-HC_RNF146; RING finger, HC subclass, found in RING finger protein 146 (RNF146) and similar proteins

  5. XM_028846791.1 → XP_028702624.1  E3 ubiquitin-protein ligase RNF146 isoform X2

    UniProtKB/TrEMBL
    A0A8J8XK00, F7GUD1, G7MQF3
    Conserved Domains (2) summary
    smart00678
    Location:103 → 175
    WWE; Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis
    cd16546
    Location:35 → 74
    RING-HC_RNF146; RING finger, HC subclass, found in RING finger protein 146 (RNF146) and similar proteins

  6. XM_015137294.2 → XP_014992780.1  E3 ubiquitin-protein ligase RNF146 isoform X1

    UniProtKB/TrEMBL
    F6SP59
    Related
    ENSMMUP00000020131.1, ENSMMUT00000021523.3
    Conserved Domains (2) summary
    smart00678
    Location:104 → 176
    WWE; Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis
    cd16546
    Location:36 → 75
    RING-HC_RNF146; RING finger, HC subclass, found in RING finger protein 146 (RNF146) and similar proteins

  7. XM_028846792.1 → XP_028702625.1  E3 ubiquitin-protein ligase RNF146 isoform X2

    UniProtKB/TrEMBL
    A0A8J8XK00, F7GUD1, G7MQF3
    Conserved Domains (2) summary
    smart00678
    Location:103 → 175
    WWE; Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis
    cd16546
    Location:35 → 74
    RING-HC_RNF146; RING finger, HC subclass, found in RING finger protein 146 (RNF146) and similar proteins
Nucleotide Protein
Heading Accession and Version

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