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HECTD4 HECT domain E3 ubiquitin protein ligase 4 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 711721, updated on 17-Aug-2024

Summary

Official Symbol
HECTD4provided by VGNC
Official Full Name
HECT domain E3 ubiquitin protein ligase 4provided by VGNC
Primary source
VGNC:VGNC:73245
See related
Ensembl:ENSMMUG00000007126
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
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Genomic context

See HECTD4 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
77
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (111864769..112093038, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (112173946..112350626, complement)

Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene low molecular weight phosphotyrosine protein phosphatase pseudogene Neighboring gene N-alpha-acetyltransferase 25, NatB auxiliary subunit Neighboring gene TRAF-type zinc finger domain containing 1 Neighboring gene protein tyrosine phosphatase non-receptor type 11 Neighboring gene ribosomal protein L6

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ubiquitin-protein transferase activity IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
probable E3 ubiquitin-protein ligase HECTD4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041764.1 Reference Mmul_10 Primary Assembly

    Range
    111864769..112093038 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028829924.1XP_028685757.1  probable E3 ubiquitin-protein ligase HECTD4 isoform X4

    UniProtKB/TrEMBL
    F6V133, F7DTU9
    Related
    ENSMMUP00000038608.3, ENSMMUT00000045572.3
    Conserved Domains (2) summary
    cd13735
    Location:23992554
    SPRY_HECT_like; SPRY domain in HECT E3
    cl27008
    Location:40194413
    HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
  2. XM_028829925.1XP_028685758.1  probable E3 ubiquitin-protein ligase HECTD4 isoform X5

    UniProtKB/TrEMBL
    F7DTU9
    Related
    ENSMMUP00000009328.4, ENSMMUT00000009939.4
    Conserved Domains (2) summary
    cd13735
    Location:23972552
    SPRY_HECT_like; SPRY domain in HECT E3
    cl27008
    Location:40174411
    HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
  3. XM_028829923.1XP_028685756.1  probable E3 ubiquitin-protein ligase HECTD4 isoform X3

    UniProtKB/TrEMBL
    F7DTU9
    Conserved Domains (2) summary
    cd13735
    Location:24062561
    SPRY_HECT_like; SPRY domain in HECT E3
    cl27008
    Location:40264420
    HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
  4. XM_028829922.1XP_028685755.1  probable E3 ubiquitin-protein ligase HECTD4 isoform X2

    UniProtKB/TrEMBL
    F7DTU9
    Related
    ENSMMUP00000067977.1, ENSMMUT00000087983.1
    Conserved Domains (2) summary
    cd13735
    Location:24082563
    SPRY_HECT_like; SPRY domain in HECT E3
    cl27008
    Location:40274421
    HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
  5. XM_028829921.1XP_028685754.1  probable E3 ubiquitin-protein ligase HECTD4 isoform X1

    UniProtKB/TrEMBL
    F7DTU9
    Conserved Domains (2) summary
    cd13735
    Location:24082563
    SPRY_HECT_like; SPRY domain in HECT E3
    cl27008
    Location:40284422
    HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
  6. XM_015152854.2XP_015008340.1  probable E3 ubiquitin-protein ligase HECTD4 isoform X6

    UniProtKB/TrEMBL
    F7DTU9
    Conserved Domains (3) summary
    smart00119
    Location:39244274
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd13735
    Location:22642419
    SPRY_HECT_like; SPRY domain in HECT E3
    cl00077
    Location:38844278
    HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
  7. XM_028829927.1XP_028685760.1  probable E3 ubiquitin-protein ligase HECTD4 isoform X8

    UniProtKB/TrEMBL
    G7N5P0
    Conserved Domains (2) summary
    cd13735
    Location:17151870
    SPRY_HECT_like; SPRY domain in HECT E3
    cl27008
    Location:33353729
    HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
  8. XM_028829926.1XP_028685759.1  probable E3 ubiquitin-protein ligase HECTD4 isoform X7

    UniProtKB/TrEMBL
    F7DTU9
    Conserved Domains (1) summary
    cd13735
    Location:24082563
    SPRY_HECT_like; SPRY domain in HECT E3