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HDAC6 histone deacetylase 6 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 711363, updated on 17-Aug-2024

Summary

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Official Symbol
HDAC6provided by VGNC
Official Full Name
histone deacetylase 6provided by VGNC
Primary source
VGNC:VGNC:73164
See related
Ensembl:ENSMMUG00000016465
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See HDAC6 in Genome Data Viewer
Location:
chromosome: X
Exon count:
30
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) X NC_041774.1 (48802330..48825970)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) X NC_027913.1 (49044106..49068065)

Chromosome X - NC_041774.1Genomic Context describing neighboring genes Neighboring gene glyoxalase domain containing 5 Neighboring gene GATA binding protein 1 Neighboring gene uncharacterized LOC114675082 Neighboring gene ES cell expressed Ras Neighboring gene proprotein convertase subtilisin/kexin type 1 inhibitor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables histone deacetylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chromatin organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of histone deacetylase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
histone deacetylase 6
NP_001181125.1
XP_014982803.1
XP_014982805.1
XP_014982806.1
XP_014982808.1
XP_014982809.1
XP_014982810.1
XP_028697651.1
XP_028697652.1
XP_028697653.1
XP_028697654.1
XP_028697655.1
XP_028697656.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001194196.2 → NP_001181125.1  histone deacetylase 6

    See identical proteins and their annotated locations for NP_001181125.1

    Status: PROVISIONAL

    Source sequence(s)
    QNVO02003165
    UniProtKB/TrEMBL
    A0A5F7ZFQ0, F7GBE5, H9ER82
    Related
    ENSMMUP00000069740.1, ENSMMUT00000099875.1
    Conserved Domains (4) summary
    cd10003
    Location:485 → 835
    HDAC6-dom2; Histone deacetylase 6, domain 2
    cd11682
    Location:99 → 435
    HDAC6-dom1; Histone deacetylase 6, domain 1
    pfam05109
    Location:838 → 1071
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam02148
    Location:1133 → 1195
    zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041774.1 Reference Mmul_10 Primary Assembly

    Range
    48802330..48825970
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015127317.2 → XP_014982803.1  histone deacetylase 6 isoform X3

    UniProtKB/TrEMBL
    F7GBF5
    Related
    ENSMMUP00000021637.4, ENSMMUT00000023129.4
    Conserved Domains (3) summary
    cd10003
    Location:531 → 881
    HDAC6-dom2; Histone deacetylase 6, domain 2
    cd11682
    Location:141 → 477
    HDAC6-dom1; Histone deacetylase 6, domain 1
    pfam02148
    Location:1179 → 1241
    zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein

  2. XM_015127322.2 → XP_014982808.1  histone deacetylase 6 isoform X1

    UniProtKB/TrEMBL
    A0A5F7ZFQ0, A0A5K1VJH7, I0FN62
    Conserved Domains (3) summary
    cd10003
    Location:489 → 839
    HDAC6-dom2; Histone deacetylase 6, domain 2
    cd11682
    Location:99 → 435
    HDAC6-dom1; Histone deacetylase 6, domain 1
    pfam02148
    Location:1137 → 1199
    zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein

  3. XM_028841818.1 → XP_028697651.1  histone deacetylase 6 isoform X2

    UniProtKB/TrEMBL
    A0A5F7ZFQ0, F7GBE5, H9ER82
    Related
    ENSMMUP00000078635.1, ENSMMUT00000084898.1
    Conserved Domains (4) summary
    cd10003
    Location:485 → 835
    HDAC6-dom2; Histone deacetylase 6, domain 2
    cd11682
    Location:99 → 435
    HDAC6-dom1; Histone deacetylase 6, domain 1
    pfam05109
    Location:838 → 1071
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam02148
    Location:1133 → 1195
    zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein

  4. XM_028841823.1 → XP_028697656.1  histone deacetylase 6 isoform X6

    UniProtKB/TrEMBL
    A0A5F7Z9U3, A0A5F7ZHA3
    Related
    ENSMMUP00000061394.1, ENSMMUT00000085908.1
    Conserved Domains (4) summary
    cd10003
    Location:434 → 784
    HDAC6-dom2; Histone deacetylase 6, domain 2
    cd11682
    Location:44 → 380
    HDAC6-dom1; Histone deacetylase 6, domain 1
    pfam05109
    Location:787 → 1020
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam02148
    Location:1082 → 1144
    zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein

  5. XM_015127319.2 → XP_014982805.1  histone deacetylase 6 isoform X1

    UniProtKB/TrEMBL
    A0A5F7ZFQ0, A0A5K1VJH7, I0FN62
    Conserved Domains (3) summary
    cd10003
    Location:489 → 839
    HDAC6-dom2; Histone deacetylase 6, domain 2
    cd11682
    Location:99 → 435
    HDAC6-dom1; Histone deacetylase 6, domain 1
    pfam02148
    Location:1137 → 1199
    zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein

  6. XM_028841822.1 → XP_028697655.1  histone deacetylase 6 isoform X2

    UniProtKB/TrEMBL
    A0A5F7ZFQ0, F7GBE5, H9ER82
    Conserved Domains (4) summary
    cd10003
    Location:485 → 835
    HDAC6-dom2; Histone deacetylase 6, domain 2
    cd11682
    Location:99 → 435
    HDAC6-dom1; Histone deacetylase 6, domain 1
    pfam05109
    Location:838 → 1071
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam02148
    Location:1133 → 1195
    zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein

  7. XM_028841821.1 → XP_028697654.1  histone deacetylase 6 isoform X2

    UniProtKB/TrEMBL
    A0A5F7ZFQ0, F7GBE5, H9ER82
    Related
    ENSMMUP00000063454.1, ENSMMUT00000079887.1
    Conserved Domains (4) summary
    cd10003
    Location:485 → 835
    HDAC6-dom2; Histone deacetylase 6, domain 2
    cd11682
    Location:99 → 435
    HDAC6-dom1; Histone deacetylase 6, domain 1
    pfam05109
    Location:838 → 1071
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam02148
    Location:1133 → 1195
    zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein

  8. XM_028841819.1 → XP_028697652.1  histone deacetylase 6 isoform X4

    UniProtKB/TrEMBL
    A0A5F7ZFQ0
    Conserved Domains (4) summary
    cd10003
    Location:503 → 853
    HDAC6-dom2; Histone deacetylase 6, domain 2
    cd11682
    Location:113 → 449
    HDAC6-dom1; Histone deacetylase 6, domain 1
    pfam05109
    Location:856 → 1089
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam02148
    Location:1151 → 1213
    zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein

  9. XM_028841820.1 → XP_028697653.1  histone deacetylase 6 isoform X5

    UniProtKB/TrEMBL
    A0A5F7ZFQ0
    Conserved Domains (4) summary
    cd10003
    Location:499 → 849
    HDAC6-dom2; Histone deacetylase 6, domain 2
    cd11682
    Location:113 → 449
    HDAC6-dom1; Histone deacetylase 6, domain 1
    pfam05109
    Location:852 → 1085
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam02148
    Location:1147 → 1209
    zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein

  10. XM_015127323.2 → XP_014982809.1  histone deacetylase 6 isoform X1

    UniProtKB/TrEMBL
    A0A5F7ZFQ0, A0A5K1VJH7, I0FN62
    Related
    ENSMMUP00000063991.1, ENSMMUT00000084196.1
    Conserved Domains (3) summary
    cd10003
    Location:489 → 839
    HDAC6-dom2; Histone deacetylase 6, domain 2
    cd11682
    Location:99 → 435
    HDAC6-dom1; Histone deacetylase 6, domain 1
    pfam02148
    Location:1137 → 1199
    zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein

  11. XM_015127320.2 → XP_014982806.1  histone deacetylase 6 isoform X1

    UniProtKB/TrEMBL
    A0A5F7ZFQ0, A0A5K1VJH7, I0FN62
    Conserved Domains (3) summary
    cd10003
    Location:489 → 839
    HDAC6-dom2; Histone deacetylase 6, domain 2
    cd11682
    Location:99 → 435
    HDAC6-dom1; Histone deacetylase 6, domain 1
    pfam02148
    Location:1137 → 1199
    zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein

  12. XM_015127324.2 → XP_014982810.1  histone deacetylase 6 isoform X1

    UniProtKB/TrEMBL
    A0A5F7ZFQ0, A0A5K1VJH7, I0FN62
    Related
    ENSMMUP00000021638.4, ENSMMUT00000023130.4
    Conserved Domains (3) summary
    cd10003
    Location:489 → 839
    HDAC6-dom2; Histone deacetylase 6, domain 2
    cd11682
    Location:99 → 435
    HDAC6-dom1; Histone deacetylase 6, domain 1
    pfam02148
    Location:1137 → 1199
    zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
Nucleotide Protein
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