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GCLC glutamate-cysteine ligase catalytic subunit [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 710508, updated on 17-Aug-2024

Summary

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Official Symbol
GCLCprovided by VGNC
Official Full Name
glutamate-cysteine ligase catalytic subunitprovided by VGNC
Primary source
VGNC:VGNC:72923
Locus tag
EGK_15023
See related
Ensembl:ENSMMUG00000008684
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See GCLC in Genome Data Viewer
Location:
chromosome: 4
Exon count:
16
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (116040781..116086499)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (54422987..54468462, complement)

Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene kelch like family member 31 Neighboring gene 60S ribosomal protein L37 pseudogene Neighboring gene uncharacterized LOC114677586 Neighboring gene homeobox protein NANOG pseudogene Neighboring gene WW domain-binding protein 11-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables glutamate-cysteine ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in glutathione biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of glutamate-cysteine ligase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
glutamate--cysteine ligase catalytic subunit
NP_001248036.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001261107.1 → NP_001248036.1  glutamate--cysteine ligase catalytic subunit

    See identical proteins and their annotated locations for NP_001248036.1

    Status: PROVISIONAL

    Source sequence(s)
    JV044209
    UniProtKB/TrEMBL
    A0A1D5QEN7, A0A8J8Y0S5, F7EZ43, G7MPM0
    Related
    ENSMMUP00000046506.2, ENSMMUT00000058362.2
    Conserved Domains (2) summary
    PRK00087
    Location:22 → 76
    PRK00087; bifunctional 4-hydroxy-3-methylbut-2-enyl diphosphate reductase/30S ribosomal protein S1
    pfam03074
    Location:236 → 608
    GCS; Glutamate-cysteine ligase

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041757.1 Reference Mmul_10 Primary Assembly

    Range
    116040781..116086499
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials