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MTA1 metastasis associated 1 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 710095, updated on 17-Aug-2024

Summary

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Official Symbol
MTA1provided by VGNC
Official Full Name
metastasis associated 1provided by VGNC
Primary source
VGNC:VGNC:74942
See related
Ensembl:ENSMMUG00000017313
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See MTA1 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
22
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (167731462..167783197)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (167818161..167843222)

Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106999596 Neighboring gene testis expressed 22 Neighboring gene cysteine rich protein 2 Neighboring gene cysteine rich protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables chromatin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histone deacetylase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription coactivator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in double-strand break repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to ionizing radiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of NuRD complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
metastasis-associated protein MTA1
Names
metastasis-associated protein MTA1 MTA1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041760.1 Reference Mmul_10 Primary Assembly

    Range
    167731462..167783197
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028851955.1 → XP_028707788.1  metastasis-associated protein MTA1 isoform X2

    UniProtKB/TrEMBL
    F7HQB3, H9ETL9
    Related
    ENSMMUP00000022782.4, ENSMMUT00000024340.4
    Conserved Domains (5) summary
    cd11661
    Location:287 → 332
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    smart00401
    Location:388 → 441
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    cd04709
    Location:3 → 188
    BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...
    pfam01448
    Location:167 → 219
    ELM2; ELM2 domain
    pfam17226
    Location:464 → 541
    MTA_R1; MTA R1 domain

  2. XM_028851954.1 → XP_028707787.1  metastasis-associated protein MTA1 isoform X1

    UniProtKB/TrEMBL
    A0A1D5Q2E5, F7HQB3, H9G1M8
    Related
    ENSMMUP00000042207.2, ENSMMUT00000073475.2
    Conserved Domains (5) summary
    cd11661
    Location:287 → 332
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    smart00401
    Location:388 → 441
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    cd04709
    Location:3 → 188
    BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...
    pfam01448
    Location:167 → 219
    ELM2; ELM2 domain
    pfam17226
    Location:464 → 541
    MTA_R1; MTA R1 domain

  3. XM_028851956.1 → XP_028707789.1  metastasis-associated protein MTA1 isoform X3

    UniProtKB/TrEMBL
    A0A1D5Q4K1, A0A1D5QT76
    Related
    ENSMMUP00000051255.2, ENSMMUT00000057723.2
    Conserved Domains (5) summary
    cd11661
    Location:270 → 315
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    smart00401
    Location:371 → 424
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    cd04709
    Location:3 → 171
    BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...
    pfam01448
    Location:150 → 202
    ELM2; ELM2 domain
    pfam17226
    Location:447 → 524
    MTA_R1; MTA R1 domain

  4. XM_028851957.1 → XP_028707790.1  metastasis-associated protein MTA1 isoform X4

    UniProtKB/TrEMBL
    A0A1D5Q4K1
    Conserved Domains (5) summary
    cd11661
    Location:266 → 311
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    smart00401
    Location:367 → 420
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    cd04709
    Location:3 → 167
    BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...
    pfam01448
    Location:146 → 198
    ELM2; ELM2 domain
    pfam17226
    Location:443 → 520
    MTA_R1; MTA R1 domain
Nucleotide Protein
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