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CENPF centromere protein F [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 709000, updated on 17-Aug-2024

Summary

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Official Symbol
CENPFprovided by VGNC
Official Full Name
centromere protein Fprovided by VGNC
Primary source
VGNC:VGNC:71009
See related
Ensembl:ENSMMUG00000015634
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See CENPF in Genome Data Viewer
Location:
chromosome: 1
Exon count:
21
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (72060563..72120213)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (151844083..151903826, complement)

Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene SET and MYND domain containing 2 Neighboring gene protein tyrosine phosphatase non-receptor type 14 Neighboring gene keratin, type I cytoskeletal 18 pseudogene Neighboring gene ubiquitin-conjugating enzyme E2 variant 1-like Neighboring gene 60S ribosomal protein L36 pseudogene Neighboring gene ubiquitin-conjugating enzyme E2 C

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables dynein complex binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription factor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in metaphase chromosome alignment IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of G2/M transition of mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in chromosome, centromeric region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in spindle pole IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
centromere protein F
Names
centromere protein F, 350/400kDa (mitosin)
centromere protein F, 350/400ka (mitosin)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041754.1 Reference Mmul_10 Primary Assembly

    Range
    72060563..72120213
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015116316.2 → XP_014971802.2  centromere protein F

    UniProtKB/TrEMBL
    F6RLX8, H9Z4G9
    Related
    ENSMMUP00000020521.4, ENSMMUT00000021938.4
    Conserved Domains (6) summary
    COG1196
    Location:2022 → 2818
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    COG4372
    Location:280 → 507
    COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]
    pfam10473
    Location:2312 → 2451
    CENP-F_leu_zip; Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
    pfam10481
    Location:1 → 307
    CENP-F_N; Cenp-F N-terminal domain
    pfam10490
    Location:2966 → 3012
    CENP-F_C_Rb_bdg; Rb-binding domain of kinetochore protein Cenp-F/LEK1
    pfam15294
    Location:2778 → 2882
    Leu_zip; Leucine zipper

  2. XM_015116322.2 → XP_014971808.2  centromere protein F

    UniProtKB/TrEMBL
    F6RLX8, H9Z4G9
    Conserved Domains (6) summary
    COG1196
    Location:2022 → 2818
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    COG4372
    Location:280 → 507
    COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]
    pfam10473
    Location:2312 → 2451
    CENP-F_leu_zip; Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
    pfam10481
    Location:1 → 307
    CENP-F_N; Cenp-F N-terminal domain
    pfam10490
    Location:2966 → 3012
    CENP-F_C_Rb_bdg; Rb-binding domain of kinetochore protein Cenp-F/LEK1
    pfam15294
    Location:2778 → 2882
    Leu_zip; Leucine zipper
Nucleotide Protein
Heading Accession and Version

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