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Slco6d1 solute carrier organic anion transporter family, member 6d1 [ Mus musculus (house mouse) ]

Gene ID: 70866, updated on 27-Nov-2024

Summary

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Official Symbol
Slco6d1provided by MGI
Official Full Name
solute carrier organic anion transporter family, member 6d1provided by MGI
Primary source
MGI:MGI:1918116
See related
Ensembl:ENSMUSG00000026336 AllianceGenome:MGI:1918116
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4921511I05Rik
Summary
Predicted to enable sodium-independent organic anion transmembrane transporter activity. Predicted to be involved in sodium-independent organic anion transport. Predicted to be active in basolateral plasma membrane. Orthologous to human SLCO6A1 (solute carrier organic anion transporter family member 6A1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Restricted expression toward testis adult (RPKM 6.0) See more
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Genomic context

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See Slco6d1 in Genome Data Viewer
Location:
1 D; 1 47.76 cM
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (98348812..98444710)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (98421087..98516985)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene predicted gene, 46078 Neighboring gene STARR-seq mESC enhancer starr_01790 Neighboring gene serine/threonine kinase 38 like pseudogene Neighboring gene predicted gene 7967 Neighboring gene STARR-seq mESC enhancer starr_01793 Neighboring gene STARR-seq mESC enhancer starr_01794 Neighboring gene STARR-seq mESC enhancer starr_01795 Neighboring gene predicted gene, 23434

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  2. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

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Homology

Clone Names

  • MGC132957, MGC132958

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables sodium-independent organic anion transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in sodium-independent organic anion transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in basolateral plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
solute carrier organic anion transporter family, member 6d1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001164233.1 → NP_001157705.1  solute carrier organic anion transporter family, member 6d1 isoform 2

    See identical proteins and their annotated locations for NP_001157705.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate exon in the 3' coding region, compared to variant 1. The resulting isoform (2) has a shorter C-terminus, compared to isoform 1.
    Source sequence(s)
    AK014872, BC112423, BY714392
    Consensus CDS
    CCDS48333.1
    UniProtKB/TrEMBL
    Q14DL2
    Related
    ENSMUSP00000123850.2, ENSMUST00000160796.2
    Conserved Domains (3) summary
    cd06174
    Location:87 → 463
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    cd01330
    Location:476 → 529
    KAZAL_SLC21; The kazal-type serine protease inhibitor domain has been detected in an extracellular loop region of solute carrier 21 (SLC21) family members (organic anion transporters) , which may regulate the specificity of anion uptake. The KAZAL_SLC21 domain is a ...
    pfam03137
    Location:86 → 643
    OATP; Organic Anion Transporter Polypeptide (OATP) family

  2. NM_027584.1 → NP_081860.1  solute carrier organic anion transporter family, member 6d1 isoform 1

    See identical proteins and their annotated locations for NP_081860.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AK014872
    Consensus CDS
    CCDS48332.1
    UniProtKB/TrEMBL
    Q9D5W6
    Related
    ENSMUSP00000027575.7, ENSMUST00000027575.13
    Conserved Domains (1) summary
    cl28910
    Location:83 → 583
    MFS; Major Facilitator Superfamily

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    98348812..98444710
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011248080.2 → XP_011246382.1  solute carrier organic anion transporter family, member 6d1 isoform X2

    See identical proteins and their annotated locations for XP_011246382.1

    Conserved Domains (1) summary
    cl28910
    Location:83 → 622
    MFS; Major Facilitator Superfamily

  2. XM_017312300.1 → XP_017167789.1  solute carrier organic anion transporter family, member 6d1 isoform X6

    UniProtKB/TrEMBL
    Q9D5W6
    Conserved Domains (1) summary
    cl28910
    Location:83 → 583
    MFS; Major Facilitator Superfamily

  3. XM_011248078.3 → XP_011246380.1  solute carrier organic anion transporter family, member 6d1 isoform X1

    Conserved Domains (1) summary
    cl28910
    Location:83 → 622
    MFS; Major Facilitator Superfamily

  4. XM_017312295.2 → XP_017167784.1  solute carrier organic anion transporter family, member 6d1 isoform X4

    Conserved Domains (1) summary
    cl28910
    Location:83 → 583
    MFS; Major Facilitator Superfamily

  5. XM_017312299.2 → XP_017167788.1  solute carrier organic anion transporter family, member 6d1 isoform X5

    Conserved Domains (1) summary
    cl28910
    Location:84 → 579
    MFS; Major Facilitator Superfamily

  6. XM_017312293.2 → XP_017167782.1  solute carrier organic anion transporter family, member 6d1 isoform X3

    Conserved Domains (1) summary
    cl28910
    Location:68 → 592
    MFS; Major Facilitator Superfamily

  7. XM_017312301.2 → XP_017167790.1  solute carrier organic anion transporter family, member 6d1 isoform X7

    Conserved Domains (1) summary
    cl28910
    Location:42 → 268
    MFS; Major Facilitator Superfamily
Nucleotide Protein Strain
Heading Accession and Version

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