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CTTN cortactin [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 708291, updated on 17-Aug-2024

Summary

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Official Symbol
CTTNprovided by VGNC
Official Full Name
cortactinprovided by VGNC
Primary source
VGNC:VGNC:71611
See related
Ensembl:ENSMMUG00000013267
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See CTTN in Genome Data Viewer
Location:
chromosome: 14
Exon count:
21
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (4378561..4418521, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (4190503..4229828, complement)

Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene SH3 and multiple ankyrin repeat domains 2 Neighboring gene programmed cell death protein 10 pseudogene Neighboring gene uncharacterized LOC106993169 Neighboring gene uncharacterized LOC114672214 Neighboring gene uncharacterized LOC106993170 Neighboring gene PTPRF interacting protein alpha 1 Neighboring gene histone H2A.Z pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of actin filament polymerization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in actin filament IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cortical actin cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lamellipodium IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in site of polarized growth IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
src substrate cortactin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001266284.1 → NP_001253213.1  src substrate cortactin

    See identical proteins and their annotated locations for NP_001253213.1

    Status: PROVISIONAL

    Source sequence(s)
    JU473475
    UniProtKB/TrEMBL
    F6ZBM4, I0FPV1
    Related
    ENSMMUP00000056496.2, ENSMMUT00000066398.2
    Conserved Domains (3) summary
    cd11959
    Location:459 → 511
    SH3_Cortactin; Src homology 3 domain of Cortactin
    pfam02218
    Location:231 → 266
    HS1_rep; Repeat in HS1/Cortactin
    cl05005
    Location:288 → 363
    TAF4; TATA Binding Protein (TBP) Associated Factor 4 (TAF4) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041767.1 Reference Mmul_10 Primary Assembly

    Range
    4378561..4418521 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015113425.2 → XP_014968911.1  src substrate cortactin isoform X3

    UniProtKB/TrEMBL
    A0A5F7Z9T8, I0FPV1
    Related
    ENSMMUP00000062325.1, ENSMMUT00000082996.1
    Conserved Domains (4) summary
    cd11959
    Location:422 → 474
    SH3_Cortactin; Src homology 3 domain of Cortactin
    pfam02218
    Location:157 → 192
    HS1_rep; Repeat in HS1/Cortactin
    pfam15927
    Location:284 → 322
    Casc1_N; Cancer susceptibility candidate 1 N-terminus
    NF033838
    Location:251 → 371
    PspC_subgroup_1; pneumococcal surface protein PspC, choline-binding form

  2. XM_015113420.2 → XP_014968906.1  src substrate cortactin isoform X1

    UniProtKB/TrEMBL
    H9FR13, I0FPV0
    Related
    ENSMMUP00000017450.4, ENSMMUT00000018629.4
    Conserved Domains (4) summary
    cd11959
    Location:496 → 548
    SH3_Cortactin; Src homology 3 domain of Cortactin
    pfam02218
    Location:157 → 192
    HS1_rep; Repeat in HS1/Cortactin
    pfam15927
    Location:358 → 396
    Casc1_N; Cancer susceptibility candidate 1 N-terminus
    NF033838
    Location:325 → 445
    PspC_subgroup_1; pneumococcal surface protein PspC, choline-binding form

  3. XM_015113423.2 → XP_014968909.1  src substrate cortactin isoform X2

    UniProtKB/TrEMBL
    A0A1D5Q8R5, A0A1D5RDP4
    Related
    ENSMMUP00000044433.2, ENSMMUT00000066526.2
    Conserved Domains (3) summary
    cd11959
    Location:475 → 527
    SH3_Cortactin; Src homology 3 domain of Cortactin
    pfam02218
    Location:157 → 192
    HS1_rep; Repeat in HS1/Cortactin
    cl05005
    Location:304 → 379
    TAF4; TATA Binding Protein (TBP) Associated Factor 4 (TAF4) is one of several TAFs that bind TBP and is involved in forming Transcription Factor IID (TFIID) complex

  4. XM_028832657.1 → XP_028688490.1  src substrate cortactin isoform X1

    UniProtKB/TrEMBL
    H9FR13, I0FPV0
    Related
    ENSMMUP00000068855.1, ENSMMUT00000104556.1
    Conserved Domains (4) summary
    cd11959
    Location:496 → 548
    SH3_Cortactin; Src homology 3 domain of Cortactin
    pfam02218
    Location:157 → 192
    HS1_rep; Repeat in HS1/Cortactin
    pfam15927
    Location:358 → 396
    Casc1_N; Cancer susceptibility candidate 1 N-terminus
    NF033838
    Location:325 → 445
    PspC_subgroup_1; pneumococcal surface protein PspC, choline-binding form

  5. XM_028832656.1 → XP_028688489.1  src substrate cortactin isoform X1

    UniProtKB/TrEMBL
    H9FR13, I0FPV0
    Related
    ENSMMUP00000058437.2, ENSMMUT00000066611.2
    Conserved Domains (4) summary
    cd11959
    Location:496 → 548
    SH3_Cortactin; Src homology 3 domain of Cortactin
    pfam02218
    Location:157 → 192
    HS1_rep; Repeat in HS1/Cortactin
    pfam15927
    Location:358 → 396
    Casc1_N; Cancer susceptibility candidate 1 N-terminus
    NF033838
    Location:325 → 445
    PspC_subgroup_1; pneumococcal surface protein PspC, choline-binding form
Nucleotide Protein
Heading Accession and Version

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