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SHANK2 SH3 and multiple ankyrin repeat domains 2 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 708192, updated on 17-Aug-2024

Summary

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Official Symbol
SHANK2provided by VGNC
Official Full Name
SH3 and multiple ankyrin repeat domains 2provided by VGNC
Primary source
VGNC:VGNC:101396
See related
Ensembl:ENSMMUG00000019736
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See SHANK2 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
26
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (3679124..4346791)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (3790023..4158060)

Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene 7-dehydrocholesterol reductase Neighboring gene actin epsilon 1 Neighboring gene uncharacterized LOC114672212 Neighboring gene programmed cell death protein 10 pseudogene Neighboring gene uncharacterized LOC106993169 Neighboring gene uncharacterized LOC114672214 Neighboring gene uncharacterized LOC106993170 Neighboring gene cortactin Neighboring gene PTPRF interacting protein alpha 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ionotropic glutamate receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables synaptic receptor adaptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in dendritic spine IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynaptic density IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
SH3 and multiple ankyrin repeat domains protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041767.1 Reference Mmul_10 Primary Assembly

    Range
    3679124..4346791
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028833089.1 → XP_028688922.1  SH3 and multiple ankyrin repeat domains protein 2

    UniProtKB/TrEMBL
    A0A1D5R8R3
    Related
    ENSMMUP00000027132.4, ENSMMUT00000028996.4
    Conserved Domains (9) summary
    cd09506
    Location:1773 → 1838
    SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
    cd11983
    Location:529 → 580
    SH3_Shank2; Src homology 3 domain of SH3 and multiple ankyrin repeat domains protein 2
    PLN03192
    Location:309 → 501
    PLN03192; Voltage-dependent potassium channel; Provisional
    PHA03095
    Location:153 → 376
    PHA03095; ankyrin-like protein; Provisional
    cd00992
    Location:624 → 717
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR00600
    Location:1162 → 1492
    rad2; DNA excision repair protein (rad2)
    sd00045
    Location:230 → 261
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:302 → 383
    Ank_2; Ankyrin repeats (3 copies)
    cd17176
    Location:55 → 142
    FERM_F0_SHANK2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in SH3 and multiple ankyrin repeat domains protein 2 (SHANK2)
Nucleotide Protein
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