U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MME membrane metalloendopeptidase [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 707667, updated on 17-Aug-2024

Summary

Official Symbol
MMEprovided by VGNC
Official Full Name
membrane metalloendopeptidaseprovided by VGNC
Primary source
VGNC:VGNC:74886
Locus tag
EGK_11980
See related
Ensembl:ENSMMUG00000006662
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as
neprilysin
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See MME in Genome Data Viewer
Location:
chromosome: 2
Exon count:
27
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (57349848..57441014)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 2 NC_027894.1 (142072337..142163500)

Chromosome 2 - NC_041755.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114676133 Neighboring gene uncharacterized LOC106997032 Neighboring gene polyadenylate-binding protein 1 pseudogene Neighboring gene small transmembrane regulator of ion transport 1

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in amyloid-beta clearance IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in protein processing IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
neprilysin
NP_001247743.1
XP_014987231.1
XP_014987232.1
XP_014987233.1
XP_014987234.1
XP_014987235.1
XP_014987238.1
XP_014987239.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001260814.1NP_001247743.1  neprilysin

    See identical proteins and their annotated locations for NP_001247743.1

    Status: PROVISIONAL

    Source sequence(s)
    JV047106
    UniProtKB/TrEMBL
    A0A1D5QKC2, A0A1D5RAN1, A0A8J8Y120, F7H3Y6, G7MJG5
    Related
    ENSMMUP00000048495.2, ENSMMUT00000063572.2
    Conserved Domains (1) summary
    cd08662
    Location:79748
    M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041755.1 Reference Mmul_10 Primary Assembly

    Range
    57349848..57441014
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015131749.2XP_014987235.1  neprilysin isoform X1

    UniProtKB/TrEMBL
    A0A1D5QKC2, A0A1D5RAN1, A0A8J8Y120, F7H3Y6, G7MJG5
    Related
    ENSMMUP00000057372.2, ENSMMUT00000071951.2
    Conserved Domains (1) summary
    cd08662
    Location:79748
    M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I
  2. XM_015131752.2XP_014987238.1  neprilysin isoform X1

    UniProtKB/TrEMBL
    A0A1D5QKC2, A0A1D5RAN1, A0A8J8Y120, F7H3Y6, G7MJG5
    Conserved Domains (1) summary
    cd08662
    Location:79748
    M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I
  3. XM_015131753.2XP_014987239.1  neprilysin isoform X1

    UniProtKB/TrEMBL
    A0A1D5QKC2, A0A1D5RAN1, A0A8J8Y120, F7H3Y6, G7MJG5
    Conserved Domains (1) summary
    cd08662
    Location:79748
    M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I
  4. XM_015131748.2XP_014987234.1  neprilysin isoform X1

    UniProtKB/TrEMBL
    A0A1D5QKC2, A0A1D5RAN1, A0A8J8Y120, F7H3Y6, G7MJG5
    Conserved Domains (1) summary
    cd08662
    Location:79748
    M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I
  5. XM_015131747.2XP_014987233.1  neprilysin isoform X1

    UniProtKB/TrEMBL
    A0A1D5QKC2, A0A1D5RAN1, A0A8J8Y120, F7H3Y6, G7MJG5
    Conserved Domains (1) summary
    cd08662
    Location:79748
    M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I
  6. XM_015131746.2XP_014987232.1  neprilysin isoform X1

    UniProtKB/TrEMBL
    A0A1D5QKC2, A0A1D5RAN1, A0A8J8Y120, F7H3Y6, G7MJG5
    Conserved Domains (1) summary
    cd08662
    Location:79748
    M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I
  7. XM_015131745.2XP_014987231.1  neprilysin isoform X1

    UniProtKB/TrEMBL
    A0A1D5QKC2, A0A1D5RAN1, A0A8J8Y120, F7H3Y6, G7MJG5
    Related
    ENSMMUP00000008763.4, ENSMMUT00000009326.4
    Conserved Domains (1) summary
    cd08662
    Location:79748
    M13; Peptidase family M13 includes neprilysin and endothelin-converting enzyme I