HSPG2 heparan sulfate proteoglycan 2 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: HSPG2provided by VGNC
Official Full Name: heparan sulfate proteoglycan 2provided by VGNC
Primary source: VGNC:VGNC:73534
See related: Ensembl:ENSMMUG00000014828
Gene type: protein coding
RefSeq status: MODEL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 1

Exon count:: 103

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	1	NC_041754.1 (202851088..202941372)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	1	NC_027893.1 (20608894..20684930, complement)

Chromosome 1 - NC_041754.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

STS-M85289 (e-PCR)
- UniSTS:38420

SHGC-74354 (e-PCR)
- UniSTS:12496

RH79675 (e-PCR)
- UniSTS:91104

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info	PubMed
enables cell adhesion molecule binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell-cell adhesion	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cell-cell junction	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: basement membrane-specific heparan sulfate proteoglycan core protein

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041754.1 Reference Mmul_10 Primary Assembly

Range

202851088..202941372

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015130367.2 → XP_014985853.2 basement membrane-specific heparan sulfate proteoglycan core protein isoform X7

UniProtKB/TrEMBL

G7MHF2

Conserved Domains (15) summary

cd05743
Location:481 → 558

Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains

cd05754
Location:1832 → 1917

Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins

smart00200
Location:140 → 254

SEA; Domain found in sea urchin sperm protein, enterokinase, agrin

smart00281
Location:1046 → 1173

LamB; Laminin B domain

smart00409
Location:2993 → 3070

IG; Immunoglobulin

smart00410
Location:2118 → 2195

IG_like; Immunoglobulin like

cd00054
Location:3913 → 3942

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

cd00055
Location:1219 → 1268

EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...

cd00110
Location:4264 → 4423

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

cd00112
Location:385 → 419

LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...

pfam00008
Location:4169 → 4199

EGF; EGF-like domain

pfam00053
Location:1336 → 1383

Laminin_EGF; Laminin EGF domain

pfam00057
Location:257 → 294

Ldl_recept_a; Low-density lipoprotein receptor domain class A

pfam07679
Location:3642 → 3719

I-set; Immunoglobulin I-set domain

cl11960
Location:3478 → 3544

Ig; Immunoglobulin domain
XM_028838327.1 → XP_028694160.1 basement membrane-specific heparan sulfate proteoglycan core protein isoform X1

UniProtKB/TrEMBL

G7MHF2

Conserved Domains (15) summary

cd05743
Location:498 → 575

Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains

cd05754
Location:1999 → 2084

Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins

smart00200
Location:140 → 253

SEA; Domain found in sea urchin sperm protein, enterokinase, agrin

smart00281
Location:1063 → 1190

LamB; Laminin B domain

smart00409
Location:2479 → 2553

IG; Immunoglobulin

smart00410
Location:2285 → 2362

IG_like; Immunoglobulin like

cd00054
Location:4086 → 4115

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

cd00055
Location:1236 → 1285

EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...

cd00110
Location:4437 → 4596

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

cd00112
Location:402 → 436

LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...

pfam00008
Location:4342 → 4372

EGF; EGF-like domain

pfam00053
Location:1353 → 1400

Laminin_EGF; Laminin EGF domain

pfam00057
Location:274 → 311

Ldl_recept_a; Low-density lipoprotein receptor domain class A

pfam07679
Location:3809 → 3886

I-set; Immunoglobulin I-set domain

cl11960
Location:3645 → 3711

Ig; Immunoglobulin domain
XM_028838335.1 → XP_028694168.1 basement membrane-specific heparan sulfate proteoglycan core protein isoform X4

UniProtKB/TrEMBL

G7MHF2

Conserved Domains (15) summary

cd05743
Location:498 → 575

Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains

cd05754
Location:1999 → 2084

Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins

smart00200
Location:140 → 253

SEA; Domain found in sea urchin sperm protein, enterokinase, agrin

smart00281
Location:1063 → 1190

LamB; Laminin B domain

smart00409
Location:2479 → 2553

IG; Immunoglobulin

smart00410
Location:2285 → 2362

IG_like; Immunoglobulin like

cd00054
Location:4080 → 4109

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

cd00055
Location:1236 → 1285

EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...

cd00110
Location:4431 → 4590

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

cd00112
Location:402 → 436

LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...

pfam00008
Location:4336 → 4366

EGF; EGF-like domain

pfam00053
Location:1353 → 1400

Laminin_EGF; Laminin EGF domain

pfam00057
Location:274 → 311

Ldl_recept_a; Low-density lipoprotein receptor domain class A

pfam07679
Location:3809 → 3886

I-set; Immunoglobulin I-set domain

cl11960
Location:3645 → 3711

Ig; Immunoglobulin domain
XM_028838332.1 → XP_028694165.1 basement membrane-specific heparan sulfate proteoglycan core protein isoform X3

UniProtKB/TrEMBL

G7MHF2

Conserved Domains (15) summary

cd05743
Location:498 → 575

Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains

cd05754
Location:1999 → 2084

Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins

smart00200
Location:140 → 253

SEA; Domain found in sea urchin sperm protein, enterokinase, agrin

smart00281
Location:1063 → 1190

LamB; Laminin B domain

smart00409
Location:2479 → 2553

IG; Immunoglobulin

smart00410
Location:2285 → 2362

IG_like; Immunoglobulin like

cd00054
Location:4084 → 4113

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

cd00055
Location:1236 → 1285

EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...

cd00110
Location:4435 → 4594

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

cd00112
Location:402 → 436

LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...

pfam00008
Location:4340 → 4370

EGF; EGF-like domain

pfam00053
Location:1353 → 1400

Laminin_EGF; Laminin EGF domain

pfam00057
Location:274 → 311

Ldl_recept_a; Low-density lipoprotein receptor domain class A

pfam07679
Location:3807 → 3884

I-set; Immunoglobulin I-set domain

cl11960
Location:3643 → 3709

Ig; Immunoglobulin domain
XM_028838345.1 → XP_028694178.1 basement membrane-specific heparan sulfate proteoglycan core protein isoform X6

UniProtKB/TrEMBL

G7MHF2

Related

ENSMMUP00000019469.4, ENSMMUT00000020806.4

Conserved Domains (15) summary

cd05743
Location:498 → 575

Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains

cd05754
Location:1849 → 1934

Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins

smart00200
Location:140 → 253

SEA; Domain found in sea urchin sperm protein, enterokinase, agrin

smart00281
Location:1063 → 1190

LamB; Laminin B domain

smart00409
Location:3010 → 3087

IG; Immunoglobulin

smart00410
Location:2135 → 2212

IG_like; Immunoglobulin like

cd00054
Location:3936 → 3965

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

cd00055
Location:1236 → 1285

EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...

cd00110
Location:4287 → 4446

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

cd00112
Location:402 → 436

LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...

pfam00008
Location:4192 → 4222

EGF; EGF-like domain

pfam00053
Location:1353 → 1400

Laminin_EGF; Laminin EGF domain

pfam00057
Location:274 → 311

Ldl_recept_a; Low-density lipoprotein receptor domain class A

pfam07679
Location:3659 → 3736

I-set; Immunoglobulin I-set domain

cl11960
Location:3495 → 3561

Ig; Immunoglobulin domain
XM_028838329.1 → XP_028694162.1 basement membrane-specific heparan sulfate proteoglycan core protein isoform X2

UniProtKB/TrEMBL

G7MHF2

Conserved Domains (15) summary

cd05743
Location:498 → 575

Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains

cd05754
Location:1998 → 2083

Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins

smart00200
Location:140 → 253

SEA; Domain found in sea urchin sperm protein, enterokinase, agrin

smart00281
Location:1062 → 1189

LamB; Laminin B domain

smart00409
Location:2478 → 2552

IG; Immunoglobulin

smart00410
Location:2284 → 2361

IG_like; Immunoglobulin like

cd00054
Location:4085 → 4114

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

cd00055
Location:1235 → 1284

EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...

cd00110
Location:4436 → 4595

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

cd00112
Location:402 → 436

LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...

pfam00008
Location:4341 → 4371

EGF; EGF-like domain

pfam00053
Location:1352 → 1399

Laminin_EGF; Laminin EGF domain

pfam00057
Location:274 → 311

Ldl_recept_a; Low-density lipoprotein receptor domain class A

pfam07679
Location:3808 → 3885

I-set; Immunoglobulin I-set domain

cl11960
Location:3644 → 3710

Ig; Immunoglobulin domain
XM_028838340.1 → XP_028694173.1 basement membrane-specific heparan sulfate proteoglycan core protein isoform X5

UniProtKB/TrEMBL

G7MHF2

Conserved Domains (15) summary

cd05743
Location:481 → 558

Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains

cd05754
Location:1982 → 2067

Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins

smart00200
Location:140 → 254

SEA; Domain found in sea urchin sperm protein, enterokinase, agrin

smart00281
Location:1046 → 1173

LamB; Laminin B domain

smart00409
Location:2462 → 2536

IG; Immunoglobulin

smart00410
Location:2268 → 2345

IG_like; Immunoglobulin like

cd00054
Location:4069 → 4098

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

cd00055
Location:1219 → 1268

EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...

cd00110
Location:4420 → 4579

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

cd00112
Location:385 → 419

LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...

pfam00008
Location:4325 → 4355

EGF; EGF-like domain

pfam00053
Location:1336 → 1383

Laminin_EGF; Laminin EGF domain

pfam00057
Location:257 → 294

Ldl_recept_a; Low-density lipoprotein receptor domain class A

pfam07679
Location:3792 → 3869

I-set; Immunoglobulin I-set domain

cl11960
Location:3628 → 3694

Ig; Immunoglobulin domain
XM_015130373.2 → XP_014985859.2 basement membrane-specific heparan sulfate proteoglycan core protein isoform X8

UniProtKB/TrEMBL

G7MHF2

Related

ENSMMUP00000040540.3, ENSMMUT00000047505.3

Conserved Domains (15) summary

cd05743
Location:481 → 558

Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains

cd05754
Location:1831 → 1916

Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins

smart00200
Location:140 → 254

SEA; Domain found in sea urchin sperm protein, enterokinase, agrin

smart00281
Location:1045 → 1172

LamB; Laminin B domain

smart00409
Location:2992 → 3069

IG; Immunoglobulin

smart00410
Location:2117 → 2194

IG_like; Immunoglobulin like

cd00054
Location:3912 → 3941

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

cd00055
Location:1218 → 1267

EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...

cd00110
Location:4263 → 4422

LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

cd00112
Location:385 → 419

LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...

pfam00008
Location:4168 → 4198

EGF; EGF-like domain

pfam00053
Location:1335 → 1382

Laminin_EGF; Laminin EGF domain

pfam00057
Location:257 → 294

Ldl_recept_a; Low-density lipoprotein receptor domain class A

pfam07679
Location:3641 → 3718

I-set; Immunoglobulin I-set domain

cl11960
Location:3477 → 3543

Ig; Immunoglobulin domain