ARAF A-Raf proto-oncogene, serine/threonine kinase [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: ARAFprovided by VGNC
Official Full Name: A-Raf proto-oncogene, serine/threonine kinaseprovided by VGNC
Primary source: VGNC:VGNC:69997
See related: Ensembl:ENSMMUG00000011418
Gene type: protein coding
RefSeq status: MODEL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: X

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	X	NC_041774.1 (47507237..47518253)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	X	NC_027913.1 (47750813..47761817)

Chromosome X - NC_041774.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH93525 (e-PCR)
- UniSTS:85565

G23742 (e-PCR)
- UniSTS:73050

GDB:182582 (e-PCR)
- UniSTS:99173

STS-M13829 (e-PCR)
- UniSTS:72051

ARAF1__4348 (e-PCR)
- UniSTS:462739

PMC193924P5 (e-PCR)
- UniSTS:271767

WI-6972 (e-PCR)
- UniSTS:18142

SGC30176 (e-PCR)
- UniSTS:47359

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein kinase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in protein phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in signal transduction	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed
located_in mitochondrion	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: serine/threonine-protein kinase A-Raf

Names: v-raf murine sarcoma 3611 viral oncogene homolog

XP_014982783.1

EC 2.7.1.-

EC 2.7.11.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041774.1 Reference Mmul_10 Primary Assembly

Range

47507237..47518253

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015127297.2 → XP_014982783.1 serine/threonine-protein kinase A-Raf

UniProtKB/TrEMBL

G7NR57, H9FU32

Related

ENSMMUP00000044688.1, ENSMMUT00000076266.2

Conserved Domains (3) summary

cd14150
Location:309 → 573

STKc_A-Raf; Catalytic domain of the Serine/Threonine Kinase, A-Raf (Rapidly Accelerated Fibrosarcoma) kinase

cd17133
Location:19 → 91

RBD_ARAF; Ras-binding domain (RBD) found in serine/threonine-protein kinase ARAF

cd20870
Location:96 → 147

C1_A_C-Raf; protein kinase C conserved region 1 (C1 domain) found in A- and C-Raf (Rapidly Accelerated Fibrosarcoma) kinases, and similar proteins