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Magea9 MAGE family member A9 [ Mus musculus (house mouse) ]

Gene ID: 70696, updated on 27-Nov-2024

Summary

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Official Symbol
Magea9provided by MGI
Official Full Name
MAGE family member A9provided by MGI
Primary source
MGI:MGI:1917946
See related
Ensembl:ENSMUSG00000031179 AllianceGenome:MGI:1917946
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
3830417A13Rik
Summary
Predicted to enable caspase binding activity and histone deacetylase binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in cytosol; endoplasmic reticulum; and nucleoplasm. Predicted to be active in nucleus. Orthologous to several human genes including MAGEA10 (MAGE family member A10). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Restricted expression toward placenta adult (RPKM 37.7) See more
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Genomic context

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See Magea9 in Genome Data Viewer
Location:
X A7.1; X 34.57 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (63217154..63222385)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (64173548..64178779)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene prothymosin alpha pseudogene Neighboring gene STARR-seq mESC enhancer starr_47267 Neighboring gene STARR-seq mESC enhancer starr_47268 Neighboring gene predicted gene 6760 Neighboring gene SLIT and NTRK-like family, member 4 Neighboring gene DMRT-like family C1c2 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen. Liakath-Ali K, et al. Nat Commun, 2014 Apr 11. PMID 24721909, Free PMC Article
  2. Mouse screen reveals multiple new genes underlying mouse and human hearing loss. Ingham NJ, et al. PLoS Biol, 2019 Apr. PMID 30973865, Free PMC Article
  3. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
  4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables caspase binding ISO
Inferred from Sequence Orthology
more info
  
enables histone deacetylase binding ISO
Inferred from Sequence Orthology
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in negative regulation of cysteine-type endopeptidase activity ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC70696

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027512.2 → NP_081788.2  uncharacterized protein LOC70696

    See identical proteins and their annotated locations for NP_081788.2

    Status: VALIDATED

    Source sequence(s)
    AK049539, AL807820
    Consensus CDS
    CCDS30166.1
    UniProtKB/TrEMBL
    Q6NV89, Q8BQJ2
    Related
    ENSMUSP00000033522.9, ENSMUST00000033522.15
    Conserved Domains (2) summary
    pfam01454
    Location:103 → 271
    MAGE; MAGE family
    pfam12440
    Location:44 → 95
    MAGE_N; Melanoma associated antigen family N terminal

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    63217154..63222385
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030251498.1 → XP_030107358.1  uncharacterized protein LOC70696 isoform X1

    UniProtKB/TrEMBL
    Q6NV89, Q8BQJ2
    Conserved Domains (2) summary
    pfam01454
    Location:103 → 271
    MAGE; MAGE family
    pfam12440
    Location:44 → 95
    MAGE_N; Melanoma associated antigen family N terminal

  2. XM_030251497.1 → XP_030107357.1  uncharacterized protein LOC70696 isoform X1

    UniProtKB/TrEMBL
    Q6NV89, Q8BQJ2
    Conserved Domains (2) summary
    pfam01454
    Location:103 → 271
    MAGE; MAGE family
    pfam12440
    Location:44 → 95
    MAGE_N; Melanoma associated antigen family N terminal
Nucleotide Protein Strain
Heading Accession and Version

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