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MTCL1 microtubule crosslinking factor 1 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 706392, updated on 17-Aug-2024

Summary

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Official Symbol
MTCL1provided by VGNC
Official Full Name
microtubule crosslinking factor 1provided by VGNC
Primary source
VGNC:VGNC:74852
See related
Ensembl:ENSMMUG00000015761
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See MTCL1 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
19
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 18 NC_041771.1 (69722590..69846639)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 18 NC_027910.1 (223081..349825, complement)

Chromosome 18 - NC_041771.1Genomic Context describing neighboring genes Neighboring gene aldose reductase-like Neighboring gene uncharacterized LOC114673856 Neighboring gene RAB12, member RAS oncogene family Neighboring gene uncharacterized LOC106994414 Neighboring gene uncharacterized LOC106994413

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in establishment or maintenance of epithelial cell apical/basal polarity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in microtubule bundle formation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of autophagy IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in apicolateral plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lateral plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in microtubule bundle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in midbody IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in spindle pole IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
microtubule cross-linking factor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041771.1 Reference Mmul_10 Primary Assembly

    Range
    69722590..69846639
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015121546.2 → XP_014977032.2  microtubule cross-linking factor 1 isoform X9

    UniProtKB/TrEMBL
    A0A1D5QQ00
    Conserved Domains (4) summary
    COG1196
    Location:792 → 938
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:1 → 317
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam11365
    Location:162 → 256
    SOGA; Protein SOGA
    pfam14818
    Location:890 → 1014
    DUF4482; Domain of unknown function (DUF4482)

  2. XM_028837989.1 → XP_028693822.1  microtubule cross-linking factor 1 isoform X7

    UniProtKB/TrEMBL
    A0A1D5QQ00
    Related
    ENSMMUP00000047800.2, ENSMMUT00000075580.2
    Conserved Domains (3) summary
    TIGR02168
    Location:14 → 343
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam11365
    Location:188 → 282
    SOGA; Protein SOGA
    pfam14818
    Location:957 → 1081
    DUF4482; Domain of unknown function (DUF4482)

  3. XM_028837983.1 → XP_028693816.1  microtubule cross-linking factor 1 isoform X1

    UniProtKB/TrEMBL
    A0A1D5R2T2
    Conserved Domains (3) summary
    TIGR02168
    Location:14 → 343
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam11365
    Location:188 → 282
    SOGA; Protein SOGA
    pfam14818
    Location:957 → 1081
    DUF4482; Domain of unknown function (DUF4482)

  4. XM_028837987.1 → XP_028693820.1  microtubule cross-linking factor 1 isoform X5

    UniProtKB/TrEMBL
    A0A1D5R2T2
    Conserved Domains (3) summary
    TIGR02168
    Location:14 → 343
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam11365
    Location:188 → 282
    SOGA; Protein SOGA
    pfam14818
    Location:957 → 1053
    DUF4482; Domain of unknown function (DUF4482)

  5. XM_028837985.1 → XP_028693818.1  microtubule cross-linking factor 1 isoform X3

    UniProtKB/TrEMBL
    A0A1D5R2T2
    Related
    ENSMMUP00000074767.1, ENSMMUT00000095942.1
    Conserved Domains (3) summary
    TIGR02168
    Location:14 → 343
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam11365
    Location:188 → 282
    SOGA; Protein SOGA
    pfam14818
    Location:947 → 1071
    DUF4482; Domain of unknown function (DUF4482)

  6. XM_028837988.1 → XP_028693821.1  microtubule cross-linking factor 1 isoform X6

    UniProtKB/TrEMBL
    A0A1D5R2T2
    Related
    ENSMMUP00000020694.4, ENSMMUT00000022121.4
    Conserved Domains (3) summary
    TIGR02168
    Location:14 → 343
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam11365
    Location:188 → 282
    SOGA; Protein SOGA
    pfam14818
    Location:916 → 1040
    DUF4482; Domain of unknown function (DUF4482)

  7. XM_028837984.1 → XP_028693817.1  microtubule cross-linking factor 1 isoform X2

    UniProtKB/TrEMBL
    A0A1D5R2T2
    Conserved Domains (3) summary
    TIGR02168
    Location:1 → 342
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam11365
    Location:187 → 281
    SOGA; Protein SOGA
    pfam14818
    Location:956 → 1080
    DUF4482; Domain of unknown function (DUF4482)

  8. XM_028837991.1 → XP_028693824.1  microtubule cross-linking factor 1 isoform X8

    UniProtKB/TrEMBL
    A0A1D5QQ00
    Conserved Domains (3) summary
    TIGR02168
    Location:1 → 317
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam11365
    Location:162 → 256
    SOGA; Protein SOGA
    pfam14818
    Location:931 → 1055
    DUF4482; Domain of unknown function (DUF4482)

  9. XM_028837986.1 → XP_028693819.1  microtubule cross-linking factor 1 isoform X4

    UniProtKB/TrEMBL
    A0A1D5R2T2
    Related
    ENSMMUP00000072270.1, ENSMMUT00000085433.1
    Conserved Domains (4) summary
    COG1196
    Location:818 → 979
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:1 → 317
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam11365
    Location:162 → 256
    SOGA; Protein SOGA
    pfam14818
    Location:931 → 1055
    DUF4482; Domain of unknown function (DUF4482)

  10. XM_028837992.1 → XP_028693825.1  microtubule cross-linking factor 1 isoform X10

    UniProtKB/TrEMBL
    A0A1D5QQ00
    Conserved Domains (4) summary
    COG1196
    Location:16 → 395
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    TIGR02168
    Location:838 → 986
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam11365
    Location:167 → 261
    SOGA; Protein SOGA
    pfam14818
    Location:936 → 1060
    DUF4482; Domain of unknown function (DUF4482)

  11. XM_028837993.1 → XP_028693826.1  microtubule cross-linking factor 1 isoform X11

    UniProtKB/TrEMBL
    G7NST4
    Conserved Domains (3) summary
    TIGR02168
    Location:709 → 857
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam11365
    Location:38 → 132
    SOGA; Protein SOGA
    pfam14818
    Location:807 → 931
    DUF4482; Domain of unknown function (DUF4482)

  12. XM_028837994.1 → XP_028693827.1  microtubule cross-linking factor 1 isoform X12

    UniProtKB/TrEMBL
    G7NST4
    Conserved Domains (3) summary
    TIGR02168
    Location:708 → 856
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam11365
    Location:37 → 131
    SOGA; Protein SOGA
    pfam14818
    Location:806 → 930
    DUF4482; Domain of unknown function (DUF4482)

  13. XM_028837995.1 → XP_028693828.1  microtubule cross-linking factor 1 isoform X13

    UniProtKB/TrEMBL
    G7NST4
    Conserved Domains (3) summary
    TIGR02168
    Location:683 → 831
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam11365
    Location:12 → 106
    SOGA; Protein SOGA
    pfam14818
    Location:781 → 905
    DUF4482; Domain of unknown function (DUF4482)
Nucleotide Protein
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