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Entrep2 endosomal transmembrane epsin interactor 2 [ Mus musculus (house mouse) ]

Gene ID: 70638, updated on 27-Nov-2024

Summary

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Official Symbol
Entrep2provided by MGI
Official Full Name
endosomal transmembrane epsin interactor 2provided by MGI
Primary source
MGI:MGI:1917888
See related
Ensembl:ENSMUSG00000030518 AllianceGenome:MGI:1917888
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Fam189a1; 5730507A09Rik
Summary
Predicted to be located in membrane. Is expressed in medulla oblongata basal plate mantle layer; pons mantle layer; thalamus mantle layer; and ventral grey horn. Orthologous to human ENTREP2 (endosomal transmembrane epsin interactor 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in cortex adult (RPKM 12.0), frontal lobe adult (RPKM 8.7) and 10 other tissues See more
Orthologs
human all
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Genomic context

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See Entrep2 in Genome Data Viewer
Location:
7 C; 7 34.7 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (64405839..64806276, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (64756091..65156528, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E4931 Neighboring gene methylmalonyl CoA epimerase Neighboring gene amyloid beta precursor protein binding family A member 2 Neighboring gene STARR-seq mESC enhancer starr_19041 Neighboring gene STARR-seq mESC enhancer starr_19042 Neighboring gene STARR-seq mESC enhancer starr_19043 Neighboring gene STARR-seq mESC enhancer starr_19044 Neighboring gene STARR-seq mESC enhancer starr_19045 Neighboring gene STARR-seq mESC enhancer starr_19046 Neighboring gene STARR-seq mESC enhancer starr_19047 Neighboring gene NSE3 homolog, SMC5-SMC6 complex component Neighboring gene predicted gene, 51521 Neighboring gene STARR-seq mESC enhancer starr_19050 Neighboring gene STARR-seq mESC enhancer starr_19051 Neighboring gene STARR-seq mESC enhancer starr_19052 Neighboring gene predicted gene, 32963 Neighboring gene STARR-seq mESC enhancer starr_19054 Neighboring gene sorting nexin 4 pseudogene Neighboring gene predicted gene, 17918

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2004 Jun 30. PMID 15368895
  2. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
protein ENTREP2
Names
family with sequence similarity 189, member A1
protein FAM189A1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_183087.4 → NP_898910.2  protein ENTREP2

    See identical proteins and their annotated locations for NP_898910.2

    Status: VALIDATED

    Source sequence(s)
    AK172974, BC049085, CJ059365, CJ060159
    Consensus CDS
    CCDS21336.2
    UniProtKB/Swiss-Prot
    Q6A044, Q8BHP9
    Related
    ENSMUSP00000113680.2, ENSMUST00000119118.8
    Conserved Domains (1) summary
    pfam04103
    Location:34 → 199
    CD20; CD20-like family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    64405839..64806276 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006541197.2 → XP_006541260.1  protein ENTREP2 isoform X1

    Conserved Domains (2) summary
    pfam05109
    Location:225 → 402
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam04103
    Location:34 → 154
    CD20; CD20-like family
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6A044.3 GenPept UniProtKB/Swiss-Prot:Q6A044

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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