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PAK3 p21 (RAC1) activated kinase 3 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 706217, updated on 5-Mar-2024

Summary

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Gene symbol
PAK3
Gene description
p21 (RAC1) activated kinase 3
See related
Ensembl:ENSMMUG00000018763
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See PAK3 in Genome Data Viewer
Location:
chromosome: X
Exon count:
23
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) X NC_041774.1 (107644668..107937809)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) X NC_027913.1 (104958747..105252221)

Chromosome X - NC_041774.1Genomic Context describing neighboring genes Neighboring gene retrotransposon Gag like 9 Neighboring gene chordin like 1 Neighboring gene calpain 6 Neighboring gene doublecortin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of axonogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase PAK 3
Names
p21 (CDKN1A)-activated kinase 3
XP_014983498.1
XP_014983499.1
XP_014983501.1
XP_014983502.1
XP_014983504.1
XP_014983505.1
XP_014983506.1
XP_014983507.1
XP_014983508.1
XP_028697989.1
XP_028697990.1
XP_028697991.1
XP_028697992.1
XP_028697993.1
XP_028697994.1
XP_028697995.1
XP_028697996.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041774.1 Reference Mmul_10 Primary Assembly

    Range
    107644668..107937809
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015128022.2 → XP_014983508.1  serine/threonine-protein kinase PAK 3 isoform X4

    UniProtKB/TrEMBL
    A0A1D5R0S6, A0A1D5R5I6, F6XUQ0, G7NT57, H9EPY7
    Related
    ENSMMUP00000024696.4, ENSMMUT00000026381.4
    Conserved Domains (2) summary
    cd06656
    Location:248 → 544
    STKc_PAK3; Catalytic domain of the Protein Serine/Threonine Kinase, p21-activated kinase 3
    pfam00786
    Location:69 → 126
    PBD; P21-Rho-binding domain

  2. XM_015128018.2 → XP_014983504.1  serine/threonine-protein kinase PAK 3 isoform X1

    UniProtKB/TrEMBL
    A0A1D5R0S6
    Conserved Domains (2) summary
    cd06647
    Location:275 → 530
    STKc_PAK_I; Catalytic domain of the Serine/Threonine Kinase, Group I p21-activated kinase
    pfam00786
    Location:69 → 141
    PBD; P21-Rho-binding domain

  3. XM_028842163.1 → XP_028697996.1  serine/threonine-protein kinase PAK 3 isoform X4

    UniProtKB/TrEMBL
    A0A1D5R0S6, A0A1D5R5I6, F6XUQ0, G7NT57, H9EPY7
    Related
    ENSMMUP00000062321.1, ENSMMUT00000108533.1
    Conserved Domains (2) summary
    cd06656
    Location:248 → 544
    STKc_PAK3; Catalytic domain of the Protein Serine/Threonine Kinase, p21-activated kinase 3
    pfam00786
    Location:69 → 126
    PBD; P21-Rho-binding domain

  4. XM_015128015.2 → XP_014983501.1  serine/threonine-protein kinase PAK 3 isoform X1

    UniProtKB/TrEMBL
    A0A1D5R0S6
    Conserved Domains (2) summary
    cd06647
    Location:275 → 530
    STKc_PAK_I; Catalytic domain of the Serine/Threonine Kinase, Group I p21-activated kinase
    pfam00786
    Location:69 → 141
    PBD; P21-Rho-binding domain

  5. XM_028842157.1 → XP_028697990.1  serine/threonine-protein kinase PAK 3 isoform X1

    UniProtKB/TrEMBL
    A0A1D5R0S6
    Conserved Domains (2) summary
    cd06647
    Location:275 → 530
    STKc_PAK_I; Catalytic domain of the Serine/Threonine Kinase, Group I p21-activated kinase
    pfam00786
    Location:69 → 141
    PBD; P21-Rho-binding domain

  6. XM_028842162.1 → XP_028697995.1  serine/threonine-protein kinase PAK 3 isoform X3

    UniProtKB/TrEMBL
    A0A1D5Q7U4, A0A1D5R0S6
    Related
    ENSMMUP00000044110.2, ENSMMUT00000078222.2
    Conserved Domains (2) summary
    cd06647
    Location:260 → 515
    STKc_PAK_I; Catalytic domain of the Serine/Threonine Kinase, Group I p21-activated kinase
    pfam00786
    Location:69 → 126
    PBD; P21-Rho-binding domain

  7. XM_028842159.1 → XP_028697992.1  serine/threonine-protein kinase PAK 3 isoform X1

    UniProtKB/TrEMBL
    A0A1D5R0S6
    Conserved Domains (2) summary
    cd06647
    Location:275 → 530
    STKc_PAK_I; Catalytic domain of the Serine/Threonine Kinase, Group I p21-activated kinase
    pfam00786
    Location:69 → 141
    PBD; P21-Rho-binding domain

  8. XM_028842156.1 → XP_028697989.1  serine/threonine-protein kinase PAK 3 isoform X1

    UniProtKB/TrEMBL
    A0A1D5R0S6
    Related
    ENSMMUP00000078285.1, ENSMMUT00000090225.1
    Conserved Domains (2) summary
    cd06647
    Location:275 → 530
    STKc_PAK_I; Catalytic domain of the Serine/Threonine Kinase, Group I p21-activated kinase
    pfam00786
    Location:69 → 141
    PBD; P21-Rho-binding domain

  9. XM_015128021.2 → XP_014983507.1  serine/threonine-protein kinase PAK 3 isoform X4

    UniProtKB/TrEMBL
    A0A1D5R0S6, A0A1D5R5I6, F6XUQ0, G7NT57, H9EPY7
    Related
    ENSMMUP00000073286.1, ENSMMUT00000079586.1
    Conserved Domains (2) summary
    cd06656
    Location:248 → 544
    STKc_PAK3; Catalytic domain of the Protein Serine/Threonine Kinase, p21-activated kinase 3
    pfam00786
    Location:69 → 126
    PBD; P21-Rho-binding domain

  10. XM_015128020.2 → XP_014983506.1  serine/threonine-protein kinase PAK 3 isoform X3

    UniProtKB/TrEMBL
    A0A1D5Q7U4, A0A1D5R0S6
    Conserved Domains (2) summary
    cd06647
    Location:260 → 515
    STKc_PAK_I; Catalytic domain of the Serine/Threonine Kinase, Group I p21-activated kinase
    pfam00786
    Location:69 → 126
    PBD; P21-Rho-binding domain

  11. XM_028842160.1 → XP_028697993.1  serine/threonine-protein kinase PAK 3 isoform X2

    UniProtKB/TrEMBL
    A0A1D5R0S6, I2CTD5
    Related
    ENSMMUP00000074250.1, ENSMMUT00000083688.1
    Conserved Domains (2) summary
    cd06656
    Location:263 → 559
    STKc_PAK3; Catalytic domain of the Protein Serine/Threonine Kinase, p21-activated kinase 3
    pfam00786
    Location:69 → 141
    PBD; P21-Rho-binding domain

  12. XM_015128019.2 → XP_014983505.1  serine/threonine-protein kinase PAK 3 isoform X2

    UniProtKB/TrEMBL
    A0A1D5R0S6, I2CTD5
    Conserved Domains (2) summary
    cd06656
    Location:263 → 559
    STKc_PAK3; Catalytic domain of the Protein Serine/Threonine Kinase, p21-activated kinase 3
    pfam00786
    Location:69 → 141
    PBD; P21-Rho-binding domain

  13. XM_015128012.2 → XP_014983498.1  serine/threonine-protein kinase PAK 3 isoform X1

    UniProtKB/TrEMBL
    A0A1D5R0S6
    Conserved Domains (2) summary
    cd06647
    Location:275 → 530
    STKc_PAK_I; Catalytic domain of the Serine/Threonine Kinase, Group I p21-activated kinase
    pfam00786
    Location:69 → 141
    PBD; P21-Rho-binding domain

  14. XM_015128013.2 → XP_014983499.1  serine/threonine-protein kinase PAK 3 isoform X1

    UniProtKB/TrEMBL
    A0A1D5R0S6
    Conserved Domains (2) summary
    cd06647
    Location:275 → 530
    STKc_PAK_I; Catalytic domain of the Serine/Threonine Kinase, Group I p21-activated kinase
    pfam00786
    Location:69 → 141
    PBD; P21-Rho-binding domain

  15. XM_028842158.1 → XP_028697991.1  serine/threonine-protein kinase PAK 3 isoform X1

    UniProtKB/TrEMBL
    A0A1D5R0S6
    Conserved Domains (2) summary
    cd06647
    Location:275 → 530
    STKc_PAK_I; Catalytic domain of the Serine/Threonine Kinase, Group I p21-activated kinase
    pfam00786
    Location:69 → 141
    PBD; P21-Rho-binding domain

  16. XM_015128016.2 → XP_014983502.1  serine/threonine-protein kinase PAK 3 isoform X1

    UniProtKB/TrEMBL
    A0A1D5R0S6
    Conserved Domains (2) summary
    cd06647
    Location:275 → 530
    STKc_PAK_I; Catalytic domain of the Serine/Threonine Kinase, Group I p21-activated kinase
    pfam00786
    Location:69 → 141
    PBD; P21-Rho-binding domain

  17. XM_028842161.1 → XP_028697994.1  serine/threonine-protein kinase PAK 3 isoform X3

    UniProtKB/TrEMBL
    A0A1D5Q7U4, A0A1D5R0S6
    Conserved Domains (2) summary
    cd06647
    Location:260 → 515
    STKc_PAK_I; Catalytic domain of the Serine/Threonine Kinase, Group I p21-activated kinase
    pfam00786
    Location:69 → 126
    PBD; P21-Rho-binding domain
Nucleotide Protein
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