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TLL1 tolloid like 1 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 705831, updated on 17-Aug-2024

Summary

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Official Symbol
TLL1provided by VGNC
Official Full Name
tolloid like 1provided by VGNC
Primary source
VGNC:VGNC:78369
See related
Ensembl:ENSMMUG00000015799
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See TLL1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
22
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 5 NC_041758.1 (163280020..163507799)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 5 NC_027897.1 (166147128..166374895)

Chromosome 5 - NC_041758.1Genomic Context describing neighboring genes Neighboring gene E3 ubiquitin-protein ligase TRIM38-like Neighboring gene uncharacterized LOC114678425 Neighboring gene SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3 Neighboring gene annexin A10

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tolloid-like protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041758.1 Reference Mmul_10 Primary Assembly

    Range
    163280020..163507799
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028848870.1 → XP_028704703.1  tolloid-like protein 1 isoform X2

    UniProtKB/TrEMBL
    F7GX95, G7MSA0
    Related
    ENSMMUP00000034571.3, ENSMMUT00000041543.3
    Conserved Domains (3) summary
    cd04281
    Location:99 → 298
    ZnMc_BMP1_TLD; Zinc-dependent metalloprotease; BMP1/TLD-like subfamily. BMP1 (Bone morphogenetic protein 1) and TLD (tolloid)-like metalloproteases play vital roles in extracellular matrix formation, by cleaving precursor proteins such as enzymes, structural proteins, ...
    pfam00431
    Location:413 → 522
    CUB; CUB domain
    pfam14670
    Location:685 → 720
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  2. XM_015139468.2 → XP_014994954.1  tolloid-like protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A1D5QYV0, G7MSA0
    Related
    ENSMMUP00000053232.2, ENSMMUT00000078531.2
    Conserved Domains (4) summary
    cd04281
    Location:148 → 347
    ZnMc_BMP1_TLD; Zinc-dependent metalloprotease; BMP1/TLD-like subfamily. BMP1 (Bone morphogenetic protein 1) and TLD (tolloid)-like metalloproteases play vital roles in extracellular matrix formation, by cleaving precursor proteins such as enzymes, structural proteins, ...
    pfam00431
    Location:462 → 571
    CUB; CUB domain
    pfam01400
    Location:155 → 348
    Astacin; Astacin (Peptidase family M12A)
    pfam14670
    Location:734 → 769
    FXa_inhibition; Coagulation Factor Xa inhibitory site
Nucleotide Protein
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