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PDE5A phosphodiesterase 5A [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 705592, updated on 17-Aug-2024

Summary

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Official Symbol
PDE5Aprovided by VGNC
Official Full Name
phosphodiesterase 5Aprovided by VGNC
Primary source
VGNC:VGNC:75918
See related
Ensembl:ENSMMUG00000007305
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See PDE5A in Genome Data Viewer
Location:
chromosome: 5
Exon count:
23
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 5 NC_041758.1 (117387207..117516195, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 5 NC_027897.1 (118317078..118446570, complement)

Chromosome 5 - NC_041758.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106998477 Neighboring gene allregulin Neighboring gene fatty acid binding protein 2 Neighboring gene uncharacterized LOC114678387 Neighboring gene small nucleolar RNA SNORA11 Neighboring gene uncharacterized LOC106998479 Neighboring gene uncharacterized LOC106998449

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3',5'-cyclic-GMP phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cGMP-specific 3',5'-cyclic phosphodiesterase
Names
phosphodiesterase 5A, cGMP-specific
XP_001099444.2
XP_001099553.4
XP_001099652.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041758.1 Reference Mmul_10 Primary Assembly

    Range
    117387207..117516195 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001099652.4 → XP_001099652.2  cGMP-specific 3',5'-cyclic phosphodiesterase isoform X1

    UniProtKB/TrEMBL
    F7F6V2, G7MRV8
    Related
    ENSMMUP00000009576.4, ENSMMUT00000010207.4
    Conserved Domains (2) summary
    smart00065
    Location:164 → 321
    GAF; Domain present in phytochromes and cGMP-specific phosphodiesterases
    pfam00233
    Location:612 → 847
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

  2. XM_001099444.4 → XP_001099444.2  cGMP-specific 3',5'-cyclic phosphodiesterase isoform X3

    UniProtKB/TrEMBL
    G7MRV8
    Conserved Domains (2) summary
    smart00065
    Location:112 → 269
    GAF; Domain present in phytochromes and cGMP-specific phosphodiesterases
    pfam00233
    Location:560 → 795
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

  3. XM_001099553.4 → XP_001099553.4  cGMP-specific 3',5'-cyclic phosphodiesterase isoform X2

    UniProtKB/TrEMBL
    A0A1D5R6Z5, G7MRV8
    Related
    ENSMMUP00000056083.2, ENSMMUT00000072826.2
    Conserved Domains (2) summary
    smart00065
    Location:122 → 279
    GAF; Domain present in phytochromes and cGMP-specific phosphodiesterases
    pfam00233
    Location:570 → 805
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
Nucleotide Protein
Heading Accession and Version

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