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PDLIM5 PDZ and LIM domain 5 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 705358, updated on 17-Aug-2024

Summary

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Official Symbol
PDLIM5provided by VGNC
Official Full Name
PDZ and LIM domain 5provided by VGNC
Primary source
VGNC:VGNC:75816
See related
Ensembl:ENSMMUG00000022246
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See PDLIM5 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
23
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 5 NC_041758.1 (92828458..93039669)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 5 NC_027897.1 (92971699..93182925)

Chromosome 5 - NC_041758.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L35a pseudogene Neighboring gene hematopoietic prostaglandin D synthase Neighboring gene bone morphogenetic protein receptor type 1B Neighboring gene unc-5 netrin receptor C

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables muscle alpha-actinin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in heart development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in muscle structure development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Z disc IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in adherens junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of filamentous actin IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in stress fiber IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
PDZ and LIM domain protein 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041758.1 Reference Mmul_10 Primary Assembly

    Range
    92828458..93039669
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015138810.2 → XP_014994296.1  PDZ and LIM domain protein 5 isoform X1

    UniProtKB/TrEMBL
    F6YVJ0
    Conserved Domains (5) summary
    cd09453
    Location:563 → 614
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd09457
    Location:622 → 673
    LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family
    cd09459
    Location:681 → 735
    LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
    cd00992
    Location:10 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:214 → 305
    DUF4749; Domain of unknown function (DUF4749)

  2. XM_015138818.2 → XP_014994304.1  PDZ and LIM domain protein 5 isoform X8

    UniProtKB/TrEMBL
    A0A5F8A0C7, G7MTE9
    Related
    ENSMMUP00000071365.1, ENSMMUT00000084119.1
    Conserved Domains (5) summary
    cd09453
    Location:431 → 482
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd09457
    Location:490 → 541
    LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family
    cd09459
    Location:549 → 603
    LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
    cd00992
    Location:10 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:214 → 305
    DUF4749; Domain of unknown function (DUF4749)

  3. XM_015138813.2 → XP_014994299.1  PDZ and LIM domain protein 5 isoform X2

    UniProtKB/TrEMBL
    F6YVJ0
    Related
    ENSMMUP00000029290.4, ENSMMUT00000031299.4
    Conserved Domains (5) summary
    cd09453
    Location:558 → 609
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd09457
    Location:617 → 668
    LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family
    cd09459
    Location:676 → 730
    LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
    cd00992
    Location:10 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:214 → 300
    DUF4749; Domain of unknown function (DUF4749)

  4. XM_028848630.1 → XP_028704463.1  PDZ and LIM domain protein 5 isoform X10

    UniProtKB/TrEMBL
    A0A5F8AJP2, G7MTE9
    Related
    ENSMMUP00000077159.1, ENSMMUT00000090410.1
    Conserved Domains (6) summary
    cd09453
    Location:426 → 477
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd09457
    Location:485 → 536
    LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family
    cd09459
    Location:544 → 598
    LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
    PHA03307
    Location:82 → 445
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00992
    Location:10 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:214 → 300
    DUF4749; Domain of unknown function (DUF4749)

  5. XM_015138814.2 → XP_014994300.1  PDZ and LIM domain protein 5 isoform X3

    UniProtKB/TrEMBL
    F6YVJ0
    Conserved Domains (5) summary
    cd09453
    Location:552 → 603
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd09457
    Location:611 → 662
    LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family
    cd09459
    Location:670 → 724
    LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
    cd00992
    Location:10 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:214 → 294
    DUF4749; Domain of unknown function (DUF4749)

  6. XM_001103447.3 → XP_001103447.1  PDZ and LIM domain protein 5 isoform X11

    UniProtKB/TrEMBL
    A0A5F7ZFI6, G7MTE9
    Related
    ENSMMUP00000064360.1, ENSMMUT00000082689.1
    Conserved Domains (6) summary
    cd09453
    Location:420 → 471
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd09457
    Location:479 → 530
    LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family
    cd09459
    Location:538 → 592
    LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
    cd00992
    Location:10 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15741
    Location:82 → 402
    LRIF1; Ligand-dependent nuclear receptor-interacting factor 1
    pfam15936
    Location:214 → 294
    DUF4749; Domain of unknown function (DUF4749)

  7. XM_015138815.2 → XP_014994301.1  PDZ and LIM domain protein 5 isoform X4

    UniProtKB/TrEMBL
    A0A5F8ADV7
    Conserved Domains (5) summary
    cd09453
    Location:454 → 505
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd09457
    Location:513 → 564
    LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family
    cd09459
    Location:572 → 626
    LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
    cd00992
    Location:10 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:105 → 196
    DUF4749; Domain of unknown function (DUF4749)

  8. XM_015138816.2 → XP_014994302.1  PDZ and LIM domain protein 5 isoform X5

    UniProtKB/TrEMBL
    A0A5F8ADV7, F6Z107
    Related
    ENSMMUP00000029288.3, ENSMMUT00000031297.3
    Conserved Domains (5) summary
    cd09453
    Location:449 → 500
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd09457
    Location:508 → 559
    LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family
    cd09459
    Location:567 → 621
    LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
    cd00992
    Location:10 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:105 → 191
    DUF4749; Domain of unknown function (DUF4749)

  9. XM_015138820.2 → XP_014994306.1  PDZ and LIM domain protein 5 isoform X12

    UniProtKB/TrEMBL
    A0A5F8ADV7
    Conserved Domains (6) summary
    PHA03381
    Location:132 → 334
    PHA03381; tegument protein VP22; Provisional
    cd09453
    Location:317 → 368
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd09459
    Location:435 → 489
    LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
    cd00992
    Location:10 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:105 → 191
    DUF4749; Domain of unknown function (DUF4749)
    cl02475
    Location:376 → 427
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  10. XM_015138817.2 → XP_014994303.1  PDZ and LIM domain protein 5 isoform X6

    UniProtKB/TrEMBL
    A0A5F8ADV7
    Conserved Domains (5) summary
    cd09453
    Location:443 → 494
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd09457
    Location:502 → 553
    LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family
    cd09459
    Location:561 → 615
    LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
    cd00992
    Location:10 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:105 → 185
    DUF4749; Domain of unknown function (DUF4749)

  11. XM_015138822.2 → XP_014994308.1  PDZ and LIM domain protein 5 isoform X13

    UniProtKB/TrEMBL
    A0A5F8ADV7
    Related
    ENSMMUP00000075124.1, ENSMMUT00000080566.1
    Conserved Domains (6) summary
    PHA03381
    Location:136 → 328
    PHA03381; tegument protein VP22; Provisional
    cd09453
    Location:311 → 362
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd09459
    Location:429 → 483
    LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
    cd00992
    Location:10 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:105 → 185
    DUF4749; Domain of unknown function (DUF4749)
    cl02475
    Location:370 → 421
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  12. XM_015138819.2 → XP_014994305.1  PDZ and LIM domain protein 5 isoform X9

    UniProtKB/TrEMBL
    A0A5F8ADV7
    Conserved Domains (5) summary
    cd09453
    Location:429 → 480
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd09457
    Location:488 → 539
    LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family
    cd09459
    Location:547 → 601
    LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
    cd00992
    Location:10 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:100 → 171
    DUF4749; Domain of unknown function (DUF4749)

  13. XM_015138823.2 → XP_014994309.2  PDZ and LIM domain protein 5 isoform X15

    UniProtKB/TrEMBL
    F6Z153
    Related
    ENSMMUP00000029283.4, ENSMMUT00000031292.4
    Conserved Domains (2) summary
    cd00992
    Location:10 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:105 → 191
    DUF4749; Domain of unknown function (DUF4749)

  14. XM_015138824.2 → XP_014994310.2  PDZ and LIM domain protein 5 isoform X16

    UniProtKB/TrEMBL
    F6Z147, F6Z153
    Related
    ENSMMUP00000029285.4, ENSMMUT00000031294.4
    Conserved Domains (2) summary
    cd00992
    Location:10 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:91 → 171
    DUF4749; Domain of unknown function (DUF4749)

  15. XM_015138811.2 → XP_014994297.1  PDZ and LIM domain protein 5 isoform X1

    UniProtKB/TrEMBL
    F6YVJ0
    Conserved Domains (5) summary
    cd09453
    Location:563 → 614
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd09457
    Location:622 → 673
    LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family
    cd09459
    Location:681 → 735
    LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
    cd00992
    Location:10 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:214 → 305
    DUF4749; Domain of unknown function (DUF4749)

  16. XM_015138812.2 → XP_014994298.1  PDZ and LIM domain protein 5 isoform X1

    UniProtKB/TrEMBL
    F6YVJ0
    Conserved Domains (5) summary
    cd09453
    Location:563 → 614
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd09457
    Location:622 → 673
    LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family
    cd09459
    Location:681 → 735
    LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
    cd00992
    Location:10 → 82
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam15936
    Location:214 → 305
    DUF4749; Domain of unknown function (DUF4749)

  17. XM_028848629.1 → XP_028704462.1  PDZ and LIM domain protein 5 isoform X7

    UniProtKB/TrEMBL
    F6YVJ0
    Conserved Domains (4) summary
    cd09453
    Location:436 → 487
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cd09457
    Location:495 → 546
    LIM2_ENH; The second LIM domain of the Enigma Homolog (ENH) family
    cd09459
    Location:554 → 608
    LIM3_ENH; The third LIM domain of the Enigma Homolog (ENH) family
    pfam15936
    Location:92 → 178
    DUF4749; Domain of unknown function (DUF4749)

  18. XM_028848631.1 → XP_028704464.1  PDZ and LIM domain protein 5 isoform X14

    Conserved Domains (2) summary
    cd09453
    Location:95 → 146
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cl02475
    Location:213 → 267
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  19. XM_028848632.1 → XP_028704465.1  PDZ and LIM domain protein 5 isoform X14

    Conserved Domains (2) summary
    cd09453
    Location:95 → 146
    LIM1_ENH; The first LIM domain of the Enigma Homolog (ENH) family
    cl02475
    Location:213 → 267
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
Nucleotide Protein
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