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PLXNA4 plexin A4 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 705098, updated on 17-Aug-2024

Summary

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Official Symbol
PLXNA4provided by VGNC
Official Full Name
plexin A4provided by VGNC
Primary source
VGNC:VGNC:76186
See related
Ensembl:ENSMMUG00000005127
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See PLXNA4 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
32
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (158450403..158900150, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (158285205..158731608, complement)

Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene F-actin-capping protein subunit alpha-1-like Neighboring gene uncharacterized LOC106997670 Neighboring gene uncharacterized LOC106997671 Neighboring gene small nucleolar RNA SNORD46 Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables semaphorin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of axonogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell shape IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in semaphorin-plexin signaling pathway involved in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of semaphorin receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
plexin-A4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041756.1 Reference Mmul_10 Primary Assembly

    Range
    158450403..158900150 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028846301.1 → XP_028702134.1  plexin-A4 isoform X2

    UniProtKB/TrEMBL
    G7MME3
    Conserved Domains (8) summary
    cd11274
    Location:39 → 511
    Sema_plexin_A4; The Sema domain, a protein interacting module, of Plexin A4
    smart00423
    Location:510 → 548
    PSI; domain found in Plexins, Semaphorins and Integrins
    cd00603
    Location:1046 → 1126
    IPT_PCSR; IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup contains IPT domains of plexins, receptors, like the plasminogen-related growth factor receptors, the hepatocyte growth factor-scatter factors, and the ...
    cd01179
    Location:859 → 942
    IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
    cd01181
    Location:944 → 1044
    IPT_plexin_repeat3; Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
    pfam01437
    Location:655 → 693
    PSI; Plexin repeat
    pfam08337
    Location:1215 → 1768
    Plexin_cytopl; Plexin cytoplasmic RasGAP domain
    cl15674
    Location:765 → 857
    IPT; Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor ...

  2. XM_015134941.2 → XP_014990427.1  plexin-A4 isoform X1

    UniProtKB/TrEMBL
    F7BXM1, G7MME3
    Related
    ENSMMUP00000006793.3, ENSMMUT00000007228.4
    Conserved Domains (10) summary
    cd11274
    Location:39 → 511
    Sema_plexin_A4; The Sema domain, a protein interacting module, of Plexin A4
    smart00423
    Location:510 → 548
    PSI; domain found in Plexins, Semaphorins and Integrins
    cd00603
    Location:1142 → 1222
    IPT_PCSR; IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup contains IPT domains of plexins, receptors, like the plasminogen-related growth factor receptors, the hepatocyte growth factor-scatter factors, and the ...
    cd01179
    Location:955 → 1038
    IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
    cd01180
    Location:858 → 953
    IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
    cd01181
    Location:1040 → 1140
    IPT_plexin_repeat3; Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
    pfam01437
    Location:804 → 856
    PSI; Plexin repeat
    pfam08337
    Location:1311 → 1864
    Plexin_cytopl; Plexin cytoplasmic RasGAP domain
    pfam17960
    Location:564 → 654
    TIG_plexin; TIG domain
    pfam18020
    Location:708 → 802
    TIG_2; TIG domain found in plexin
Nucleotide Protein
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