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Bbx bobby sox HMG box containing [ Mus musculus (house mouse) ]

Gene ID: 70508, updated on 27-Nov-2024

Summary

Official Symbol
Bbxprovided by MGI
Official Full Name
bobby sox HMG box containingprovided by MGI
Primary source
MGI:MGI:1917758
See related
Ensembl:ENSMUSG00000022641 AllianceGenome:MGI:1917758
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
5530401J07Rik; 5730403O13Rik
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within bone development. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; dorsal root ganglion; early conceptus; genitourinary system; and sensory organ. Orthologous to human BBX (BBX high mobility group box domain containing). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in placenta adult (RPKM 16.6), testis adult (RPKM 10.8) and 23 other tissues See more
Orthologs
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Genomic context

See Bbx in Genome Data Viewer
Location:
16 B5; 16 31.35 cM
Exon count:
26
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (50012207..50252829, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (50191844..50432466, complement)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene predicted gene 4827 Neighboring gene predicted gene, 32101 Neighboring gene STARR-seq mESC enhancer starr_40979 Neighboring gene STARR-seq mESC enhancer starr_40980 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene STARR-seq mESC enhancer starr_40982 Neighboring gene STARR-seq mESC enhancer starr_40984 Neighboring gene STARR-seq mESC enhancer starr_40987 Neighboring gene STARR-positive B cell enhancer mm9_chr16:50432445-50432746 Neighboring gene STARR-seq mESC enhancer starr_40989 Neighboring gene STARR-seq mESC enhancer starr_40990 Neighboring gene predicted gene, 32231 Neighboring gene predicted gene, 41459

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (3)  1 citation

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Process Evidence Code Pubs
acts_upstream_of_or_within bone development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
HMG box transcription factor BBX
Names
HMG box-containing protein 2
bobby sox homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001347240.1NP_001334169.1  HMG box transcription factor BBX isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC154781, AK029747, CT571273
    Consensus CDS
    CCDS84241.1
    UniProtKB/Swiss-Prot
    Q8VBW5
    Related
    ENSMUSP00000086826.4, ENSMUST00000089404.10
    Conserved Domains (2) summary
    cd01388
    Location:79150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190322
    DUF2028; Domain of unknown function (DUF2028)
  2. NM_027444.3NP_081720.2  HMG box transcription factor BBX isoform 1

    See identical proteins and their annotated locations for NP_081720.2

    Status: VALIDATED

    Source sequence(s)
    AC109627, AC113067, AC154781, CT571273
    Consensus CDS
    CCDS37354.1
    UniProtKB/Swiss-Prot
    B8JK46, B8JK47, B8JK48, B8JK49, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VBW5, Q8VI48, Q8VI49, Q8VI50, Q9CS94
    Related
    ENSMUSP00000119238.2, ENSMUST00000138166.8
    Conserved Domains (2) summary
    cd01388
    Location:79150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190322
    DUF2028; Domain of unknown function (DUF2028)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    50012207..50252829 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030249277.2XP_030105137.1  HMG box transcription factor BBX isoform X3

    UniProtKB/Swiss-Prot
    B8JK46, B8JK47, B8JK48, B8JK49, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VBW5, Q8VI48, Q8VI49, Q8VI50, Q9CS94
    Conserved Domains (2) summary
    cd01388
    Location:79150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190322
    DUF2028; Domain of unknown function (DUF2028)
  2. XM_011246009.3XP_011244311.1  HMG box transcription factor BBX isoform X5

    See identical proteins and their annotated locations for XP_011244311.1

    UniProtKB/Swiss-Prot
    Q8VBW5
    Conserved Domains (2) summary
    cd01388
    Location:79150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190322
    DUF2028; Domain of unknown function (DUF2028)
  3. XM_006522546.3XP_006522609.1  HMG box transcription factor BBX isoform X1

    See identical proteins and their annotated locations for XP_006522609.1

    Conserved Domains (2) summary
    cd01388
    Location:79150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190322
    DUF2028; Domain of unknown function (DUF2028)
  4. XM_017317130.3XP_017172619.1  HMG box transcription factor BBX isoform X3

    UniProtKB/Swiss-Prot
    B8JK46, B8JK47, B8JK48, B8JK49, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VBW5, Q8VI48, Q8VI49, Q8VI50, Q9CS94
    Conserved Domains (2) summary
    cd01388
    Location:79150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190322
    DUF2028; Domain of unknown function (DUF2028)
  5. XM_030249281.2XP_030105141.1  HMG box transcription factor BBX isoform X6

    Conserved Domains (2) summary
    cd01388
    Location:79150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190295
    DUF2028; Domain of unknown function (DUF2028)
  6. XM_011246008.4XP_011244310.1  HMG box transcription factor BBX isoform X3

    See identical proteins and their annotated locations for XP_011244310.1

    UniProtKB/Swiss-Prot
    B8JK46, B8JK47, B8JK48, B8JK49, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VBW5, Q8VI48, Q8VI49, Q8VI50, Q9CS94
    Related
    ENSMUSP00000110132.2, ENSMUST00000114488.8
    Conserved Domains (2) summary
    cd01388
    Location:79150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190322
    DUF2028; Domain of unknown function (DUF2028)
  7. XM_006522549.5XP_006522612.1  HMG box transcription factor BBX isoform X1

    See identical proteins and their annotated locations for XP_006522612.1

    Conserved Domains (2) summary
    cd01388
    Location:79150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190322
    DUF2028; Domain of unknown function (DUF2028)
  8. XM_030249275.2XP_030105135.1  HMG box transcription factor BBX isoform X1

    Conserved Domains (2) summary
    cd01388
    Location:79150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190322
    DUF2028; Domain of unknown function (DUF2028)
  9. XM_006522547.5XP_006522610.1  HMG box transcription factor BBX isoform X1

    See identical proteins and their annotated locations for XP_006522610.1

    Conserved Domains (2) summary
    cd01388
    Location:79150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190322
    DUF2028; Domain of unknown function (DUF2028)
  10. XM_036160122.1XP_036016015.1  HMG box transcription factor BBX isoform X2

    Conserved Domains (2) summary
    cd01388
    Location:79150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190295
    DUF2028; Domain of unknown function (DUF2028)
  11. XM_036160123.1XP_036016016.1  HMG box transcription factor BBX isoform X2

    Conserved Domains (2) summary
    cd01388
    Location:79150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190295
    DUF2028; Domain of unknown function (DUF2028)
  12. XM_036160118.1XP_036016011.1  HMG box transcription factor BBX isoform X1

    Conserved Domains (2) summary
    cd01388
    Location:79150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190322
    DUF2028; Domain of unknown function (DUF2028)
  13. XM_006522544.5XP_006522607.1  HMG box transcription factor BBX isoform X1

    See identical proteins and their annotated locations for XP_006522607.1

    Conserved Domains (2) summary
    cd01388
    Location:79150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190322
    DUF2028; Domain of unknown function (DUF2028)
  14. XM_006522545.5XP_006522608.1  HMG box transcription factor BBX isoform X1

    See identical proteins and their annotated locations for XP_006522608.1

    Conserved Domains (2) summary
    cd01388
    Location:79150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190322
    DUF2028; Domain of unknown function (DUF2028)
  15. XM_006522554.5XP_006522617.1  HMG box transcription factor BBX isoform X1

    See identical proteins and their annotated locations for XP_006522617.1

    Conserved Domains (2) summary
    cd01388
    Location:79150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190322
    DUF2028; Domain of unknown function (DUF2028)
  16. XM_036160120.1XP_036016013.1  HMG box transcription factor BBX isoform X1

    Conserved Domains (2) summary
    cd01388
    Location:79150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190322
    DUF2028; Domain of unknown function (DUF2028)
  17. XM_011246006.4XP_011244308.1  HMG box transcription factor BBX isoform X1

    See identical proteins and their annotated locations for XP_011244308.1

    Conserved Domains (2) summary
    cd01388
    Location:79150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190322
    DUF2028; Domain of unknown function (DUF2028)
  18. XM_036160126.1XP_036016019.1  HMG box transcription factor BBX isoform X7

    Related
    ENSMUSP00000066384.7, ENSMUST00000066037.13
    Conserved Domains (2) summary
    cd01388
    Location:54112
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:152257
    DUF2028; Domain of unknown function (DUF2028)
  19. XM_030249278.2XP_030105138.1  HMG box transcription factor BBX isoform X4

    Conserved Domains (2) summary
    cd01388
    Location:54112
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:152284
    DUF2028; Domain of unknown function (DUF2028)
  20. XM_011246005.4XP_011244307.1  HMG box transcription factor BBX isoform X1

    See identical proteins and their annotated locations for XP_011244307.1

    Conserved Domains (2) summary
    cd01388
    Location:79150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190322
    DUF2028; Domain of unknown function (DUF2028)
  21. XM_006522543.5XP_006522606.1  HMG box transcription factor BBX isoform X1

    See identical proteins and their annotated locations for XP_006522606.1

    Conserved Domains (2) summary
    cd01388
    Location:79150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190322
    DUF2028; Domain of unknown function (DUF2028)
  22. XM_006522553.5XP_006522616.1  HMG box transcription factor BBX isoform X1

    See identical proteins and their annotated locations for XP_006522616.1

    Conserved Domains (2) summary
    cd01388
    Location:79150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190322
    DUF2028; Domain of unknown function (DUF2028)
  23. XM_036160121.1XP_036016014.1  HMG box transcription factor BBX isoform X2

    Conserved Domains (2) summary
    cd01388
    Location:79150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190295
    DUF2028; Domain of unknown function (DUF2028)
  24. XM_006522561.5XP_006522624.1  HMG box transcription factor BBX isoform X4

    See identical proteins and their annotated locations for XP_006522624.1

    Conserved Domains (2) summary
    cd01388
    Location:54112
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:152284
    DUF2028; Domain of unknown function (DUF2028)
  25. XM_006522560.5XP_006522623.1  HMG box transcription factor BBX isoform X4

    See identical proteins and their annotated locations for XP_006522623.1

    Conserved Domains (2) summary
    cd01388
    Location:54112
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:152284
    DUF2028; Domain of unknown function (DUF2028)
  26. XM_011246007.4XP_011244309.1  HMG box transcription factor BBX isoform X2

    Conserved Domains (2) summary
    cd01388
    Location:79150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190295
    DUF2028; Domain of unknown function (DUF2028)
  27. XM_006522555.5XP_006522618.1  HMG box transcription factor BBX isoform X1

    See identical proteins and their annotated locations for XP_006522618.1

    Conserved Domains (2) summary
    cd01388
    Location:79150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190322
    DUF2028; Domain of unknown function (DUF2028)
  28. XM_030249279.2XP_030105139.1  HMG box transcription factor BBX isoform X4

    Conserved Domains (2) summary
    cd01388
    Location:54112
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:152284
    DUF2028; Domain of unknown function (DUF2028)
  29. XM_036160116.1XP_036016009.1  HMG box transcription factor BBX isoform X1

    Conserved Domains (2) summary
    cd01388
    Location:79150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190322
    DUF2028; Domain of unknown function (DUF2028)
  30. XM_030249274.2XP_030105134.1  HMG box transcription factor BBX isoform X1

    Conserved Domains (2) summary
    cd01388
    Location:79150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190322
    DUF2028; Domain of unknown function (DUF2028)
  31. XM_036160117.1XP_036016010.1  HMG box transcription factor BBX isoform X1

    Conserved Domains (2) summary
    cd01388
    Location:79150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190322
    DUF2028; Domain of unknown function (DUF2028)
  32. XM_006522548.5XP_006522611.1  HMG box transcription factor BBX isoform X1

    See identical proteins and their annotated locations for XP_006522611.1

    Conserved Domains (2) summary
    cd01388
    Location:79150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190322
    DUF2028; Domain of unknown function (DUF2028)
  33. XM_036160125.1XP_036016018.1  HMG box transcription factor BBX isoform X5

    Related
    ENSMUSP00000086821.5, ENSMUST00000089399.11
    Conserved Domains (2) summary
    cd01388
    Location:79150
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam09667
    Location:190322
    DUF2028; Domain of unknown function (DUF2028)