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TLN2 talin 2 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 705008, updated on 17-Aug-2024

Summary

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Official Symbol
TLN2provided by VGNC
Official Full Name
talin 2provided by VGNC
Primary source
VGNC:VGNC:78385
See related
Ensembl:ENSMMUG00000011503
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See TLN2 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
63
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (38835053..39298086)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (38972162..39437165)

Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene golgin subfamily A member 2 Neighboring gene microRNA mir-7197 Neighboring gene microRNA mir-190a Neighboring gene nuclease-sensitive element-binding protein 1-like Neighboring gene tropomyosin 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables structural constituent of cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in ruffle IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
talin-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041760.1 Reference Mmul_10 Primary Assembly

    Range
    38835053..39298086
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015142408.2 → XP_014997894.1  talin-2 isoform X1

    UniProtKB/TrEMBL
    F7C628, F7FLQ7
    Conserved Domains (9) summary
    cd12150
    Location:1656 → 1827
    talin-RS; rod-segment of the talin C-terminal domain
    smart00307
    Location:2337 → 2547
    ILWEQ; I/LWEQ domain
    cd10569
    Location:312 → 403
    FERM_C_Talin; FERM domain C-lobe/F3 of Talin
    pfam08913
    Location:1850 → 1974
    VBS; Vinculin Binding Site
    cd17172
    Location:4 → 87
    FERM_F0_TLN2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in Talin-2 (TLN2)
    cd17174
    Location:88 → 199
    FERM_F1_TLN2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in Talin-2 (TLN2)
    pfam00373
    Location:209 → 316
    FERM_M; FERM central domain
    pfam09141
    Location:494 → 655
    Talin_middle; Talin, middle domain
    cl19756
    Location:689 → 765
    I_LWEQ; I/LWEQ domain

  2. XM_015142407.2 → XP_014997893.1  talin-2 isoform X1

    UniProtKB/TrEMBL
    F7C628, F7FLQ7
    Conserved Domains (9) summary
    cd12150
    Location:1656 → 1827
    talin-RS; rod-segment of the talin C-terminal domain
    smart00307
    Location:2337 → 2547
    ILWEQ; I/LWEQ domain
    cd10569
    Location:312 → 403
    FERM_C_Talin; FERM domain C-lobe/F3 of Talin
    pfam08913
    Location:1850 → 1974
    VBS; Vinculin Binding Site
    cd17172
    Location:4 → 87
    FERM_F0_TLN2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in Talin-2 (TLN2)
    cd17174
    Location:88 → 199
    FERM_F1_TLN2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in Talin-2 (TLN2)
    pfam00373
    Location:209 → 316
    FERM_M; FERM central domain
    pfam09141
    Location:494 → 655
    Talin_middle; Talin, middle domain
    cl19756
    Location:689 → 765
    I_LWEQ; I/LWEQ domain

  3. XM_015142409.2 → XP_014997895.1  talin-2 isoform X1

    UniProtKB/TrEMBL
    F7C628, F7FLQ7
    Conserved Domains (9) summary
    cd12150
    Location:1656 → 1827
    talin-RS; rod-segment of the talin C-terminal domain
    smart00307
    Location:2337 → 2547
    ILWEQ; I/LWEQ domain
    cd10569
    Location:312 → 403
    FERM_C_Talin; FERM domain C-lobe/F3 of Talin
    pfam08913
    Location:1850 → 1974
    VBS; Vinculin Binding Site
    cd17172
    Location:4 → 87
    FERM_F0_TLN2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in Talin-2 (TLN2)
    cd17174
    Location:88 → 199
    FERM_F1_TLN2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in Talin-2 (TLN2)
    pfam00373
    Location:209 → 316
    FERM_M; FERM central domain
    pfam09141
    Location:494 → 655
    Talin_middle; Talin, middle domain
    cl19756
    Location:689 → 765
    I_LWEQ; I/LWEQ domain

  4. XM_028851004.1 → XP_028706837.1  talin-2 isoform X1

    UniProtKB/TrEMBL
    F7C628, F7FLQ7
    Conserved Domains (9) summary
    cd12150
    Location:1656 → 1827
    talin-RS; rod-segment of the talin C-terminal domain
    smart00307
    Location:2337 → 2547
    ILWEQ; I/LWEQ domain
    cd10569
    Location:312 → 403
    FERM_C_Talin; FERM domain C-lobe/F3 of Talin
    pfam08913
    Location:1850 → 1974
    VBS; Vinculin Binding Site
    cd17172
    Location:4 → 87
    FERM_F0_TLN2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in Talin-2 (TLN2)
    cd17174
    Location:88 → 199
    FERM_F1_TLN2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in Talin-2 (TLN2)
    pfam00373
    Location:209 → 316
    FERM_M; FERM central domain
    pfam09141
    Location:494 → 655
    Talin_middle; Talin, middle domain
    cl19756
    Location:689 → 765
    I_LWEQ; I/LWEQ domain

  5. XM_028851003.1 → XP_028706836.1  talin-2 isoform X1

    UniProtKB/TrEMBL
    F7C628, F7FLQ7
    Conserved Domains (9) summary
    cd12150
    Location:1656 → 1827
    talin-RS; rod-segment of the talin C-terminal domain
    smart00307
    Location:2337 → 2547
    ILWEQ; I/LWEQ domain
    cd10569
    Location:312 → 403
    FERM_C_Talin; FERM domain C-lobe/F3 of Talin
    pfam08913
    Location:1850 → 1974
    VBS; Vinculin Binding Site
    cd17172
    Location:4 → 87
    FERM_F0_TLN2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in Talin-2 (TLN2)
    cd17174
    Location:88 → 199
    FERM_F1_TLN2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in Talin-2 (TLN2)
    pfam00373
    Location:209 → 316
    FERM_M; FERM central domain
    pfam09141
    Location:494 → 655
    Talin_middle; Talin, middle domain
    cl19756
    Location:689 → 765
    I_LWEQ; I/LWEQ domain

  6. XM_015142411.2 → XP_014997897.1  talin-2 isoform X1

    UniProtKB/TrEMBL
    F7C628, F7FLQ7
    Conserved Domains (9) summary
    cd12150
    Location:1656 → 1827
    talin-RS; rod-segment of the talin C-terminal domain
    smart00307
    Location:2337 → 2547
    ILWEQ; I/LWEQ domain
    cd10569
    Location:312 → 403
    FERM_C_Talin; FERM domain C-lobe/F3 of Talin
    pfam08913
    Location:1850 → 1974
    VBS; Vinculin Binding Site
    cd17172
    Location:4 → 87
    FERM_F0_TLN2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in Talin-2 (TLN2)
    cd17174
    Location:88 → 199
    FERM_F1_TLN2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in Talin-2 (TLN2)
    pfam00373
    Location:209 → 316
    FERM_M; FERM central domain
    pfam09141
    Location:494 → 655
    Talin_middle; Talin, middle domain
    cl19756
    Location:689 → 765
    I_LWEQ; I/LWEQ domain

  7. XM_028851005.1 → XP_028706838.1  talin-2 isoform X2

    UniProtKB/TrEMBL
    A0A1D5QQ80, F7C628, F7FLQ7
    Related
    ENSMMUP00000050207.2, ENSMMUT00000057755.2
    Conserved Domains (9) summary
    cd12150
    Location:1656 → 1827
    talin-RS; rod-segment of the talin C-terminal domain
    smart00307
    Location:2337 → 2532
    ILWEQ; I/LWEQ domain
    cd10569
    Location:312 → 403
    FERM_C_Talin; FERM domain C-lobe/F3 of Talin
    pfam08913
    Location:1850 → 1974
    VBS; Vinculin Binding Site
    cd17172
    Location:4 → 87
    FERM_F0_TLN2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in Talin-2 (TLN2)
    cd17174
    Location:88 → 199
    FERM_F1_TLN2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in Talin-2 (TLN2)
    pfam00373
    Location:209 → 316
    FERM_M; FERM central domain
    pfam09141
    Location:494 → 655
    Talin_middle; Talin, middle domain
    cl19756
    Location:689 → 765
    I_LWEQ; I/LWEQ domain

  8. XM_028851006.1 → XP_028706839.1  talin-2 isoform X3

    UniProtKB/TrEMBL
    G7MXL3
    Conserved Domains (8) summary
    cd12150
    Location:1656 → 1827
    talin-RS; rod-segment of the talin C-terminal domain
    cd10569
    Location:312 → 403
    FERM_C_Talin; FERM domain C-lobe/F3 of Talin
    pfam00373
    Location:209 → 316
    FERM_M; FERM central domain
    pfam08913
    Location:1850 → 1974
    VBS; Vinculin Binding Site
    pfam09141
    Location:494 → 655
    Talin_middle; Talin, middle domain
    cd17172
    Location:4 → 87
    FERM_F0_TLN2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in Talin-2 (TLN2)
    cd17174
    Location:88 → 199
    FERM_F1_TLN2; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in Talin-2 (TLN2)
    cl19756
    Location:706 → 832
    I_LWEQ; I/LWEQ domain
Nucleotide Protein
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