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NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 704451, updated on 17-Aug-2024

Summary

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Official Symbol
NHLRC1provided by VGNC
Official Full Name
NHL repeat containing E3 ubiquitin protein ligase 1provided by VGNC
Primary source
VGNC:VGNC:75229
Locus tag
EGK_14504
See related
Ensembl:ENSMMUG00000016626
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See NHLRC1 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
1
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (151840994..151845830)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (18519390..18522264, complement)

Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene lysine demethylase 1B Neighboring gene thiopurine S-methyltransferase Neighboring gene uncharacterized LOC114677690 Neighboring gene kinesin family member 13A Neighboring gene small nuclear ribonucleoprotein E pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables translation repressor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of translation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein polyubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase NHLRC1
Names
NHL repeat containing 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041757.1 Reference Mmul_10 Primary Assembly

    Range
    151840994..151845830
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001097330.4 → XP_001097330.1  E3 ubiquitin-protein ligase NHLRC1

    See identical proteins and their annotated locations for XP_001097330.1

    UniProtKB/TrEMBL
    A0A8J8XAW9, F6TPH3, G7MQT2
    Related
    ENSMMUP00000021863.1, ENSMMUT00000023366.3
    Conserved Domains (3) summary
    cd14961
    Location:118 → 391
    NHL_TRIM32_like; NHL repeat domain of the tripartite motif-containing protein 32 (TRIM32) and related proteins
    pfam14634
    Location:25 → 73
    zf-RING_5; zinc-RING finger domain
    sd00039
    Location:178 → 211
    7WD40; WD40 repeat [structural motif]
Nucleotide Protein
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Gene LinkOut

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Research Materials