LNPEP leucyl and cystinyl aminopeptidase [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: LNPEPprovided by VGNC
Official Full Name: leucyl and cystinyl aminopeptidaseprovided by VGNC
Primary source: VGNC:VGNC:74438
See related: Ensembl:ENSMMUG00000018542
Gene type: protein coding
RefSeq status: MODEL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 18

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	6	NC_041759.1 (93772463..93880359)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	6	NC_027898.1 (93907226..94008043)

Chromosome 6 - NC_041759.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH123520 (e-PCR)
- UniSTS:135938

G60101 (e-PCR)
- UniSTS:137229

SGC38194 (e-PCR)
- UniSTS:72216

AU048745 (e-PCR)
- UniSTS:145195

WI-14824 (e-PCR)
- UniSTS:16431

NoName (e-PCR)
- UniSTS:484431

RH93950 (e-PCR)
- UniSTS:92547

SHGC-82127 (e-PCR)
- UniSTS:103047

RH102413 (e-PCR)
- UniSTS:96747

D5S1849 (e-PCR)
- UniSTS:20972

D5S1627E (e-PCR)
- UniSTS:151037

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables metalloaminopeptidase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables peptide binding	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in peptide catabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in proteolysis	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: leucyl-cystinyl aminopeptidase

XP_001092287.3

EC 3.4.11.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041759.1 Reference Mmul_10 Primary Assembly

Range

93772463..93880359

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_001092287.4 → XP_001092287.3 leucyl-cystinyl aminopeptidase

UniProtKB/TrEMBL

A0A5S6R6J0, A0A8J8YRS7, F7A1I2, G7MVH1, H9FUD3

Related

ENSMMUP00000024398.3, ENSMMUT00000026071.4

Conserved Domains (2) summary

cd09601
Location:175 → 612

M1_APN-Q_like; Peptidase M1 aminopeptidase N catalytic domain family which includes aminopeptidase N (APN), aminopeptidase Q (APQ), tricorn interacting factor F3, and endoplasmic reticulum aminopeptidase 1 (ERAP1)

pfam11838
Location:689 → 1009

ERAP1_C; ERAP1-like C-terminal domain