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PALS2 protein associated with LIN7 2, MAGUK p55 family member [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 703560, updated on 17-Aug-2024

Summary

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Official Symbol
PALS2provided by VGNC
Official Full Name
protein associated with LIN7 2, MAGUK p55 family memberprovided by VGNC
Primary source
VGNC:VGNC:74790
Locus tag
EGK_13848
See related
Ensembl:ENSMMUG00000016936
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as
MPP6
Orthologs
human mouse all
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Genomic context

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See PALS2 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
17
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (90458738..90562019, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (83532533..83637049, complement)

Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene oxysterol binding protein like 3 Neighboring gene gasdermin E Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC106997488

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell-cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein PALS2; MAGUK p55 subfamily member 6
Names
membrane palmitoylated protein 6
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
protein associated with LIN7 2, MAGUK family member

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001260678.2 → NP_001247607.1  protein PALS2

    See identical proteins and their annotated locations for NP_001247607.1

    Status: PROVISIONAL

    Source sequence(s)
    JU334957
    UniProtKB/TrEMBL
    F6W428, F7CCP1, F7CCP7
    Related
    ENSMMUP00000022271.2, ENSMMUT00000023794.4
    Conserved Domains (5) summary
    smart00569
    Location:2 → 55
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12038
    Location:219 → 279
    SH3_MPP6; Src Homology 3 domain of Membrane Protein, Palmitoylated 6 (or MAGUK p55 subfamily member 6)
    cd00992
    Location:133 → 206
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:337 → 527
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:57 → 108
    L27; L27 domain

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041756.1 Reference Mmul_10 Primary Assembly

    Range
    90458738..90562019 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015133853.2 → XP_014989339.1  MAGUK p55 subfamily member 6 isoform X1

    UniProtKB/TrEMBL
    A0A1D5R1Q9, F6W428
    Conserved Domains (5) summary
    smart00569
    Location:2 → 55
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd00992
    Location:133 → 206
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:351 → 541
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:57 → 108
    L27; L27 domain
    cl17036
    Location:233 → 293
    SH3; Src Homology 3 domain superfamily

  2. XM_015133857.2 → XP_014989343.1  MAGUK p55 subfamily member 6 isoform X1

    UniProtKB/TrEMBL
    A0A1D5R1Q9, F6W428
    Conserved Domains (5) summary
    smart00569
    Location:2 → 55
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd00992
    Location:133 → 206
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:351 → 541
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:57 → 108
    L27; L27 domain
    cl17036
    Location:233 → 293
    SH3; Src Homology 3 domain superfamily

  3. XM_015133856.1 → XP_014989342.1  MAGUK p55 subfamily member 6 isoform X2

    UniProtKB/TrEMBL
    F6W428, F7CCP1, F7CCP7
    Related
    ENSMMUP00000022270.4, ENSMMUT00000023793.4
    Conserved Domains (5) summary
    smart00569
    Location:2 → 55
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd12038
    Location:219 → 279
    SH3_MPP6; Src Homology 3 domain of Membrane Protein, Palmitoylated 6 (or MAGUK p55 subfamily member 6)
    cd00992
    Location:133 → 206
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:337 → 527
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:57 → 108
    L27; L27 domain

  4. XM_028844893.1 → XP_028700726.1  MAGUK p55 subfamily member 6 isoform X1

    UniProtKB/TrEMBL
    A0A1D5R1Q9, F6W428
    Related
    ENSMMUP00000054243.2, ENSMMUT00000058929.2
    Conserved Domains (5) summary
    smart00569
    Location:2 → 55
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd00992
    Location:133 → 206
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:351 → 541
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:57 → 108
    L27; L27 domain
    cl17036
    Location:233 → 293
    SH3; Src Homology 3 domain superfamily

  5. XM_015133855.2 → XP_014989341.1  MAGUK p55 subfamily member 6 isoform X1

    UniProtKB/TrEMBL
    A0A1D5R1Q9, F6W428
    Conserved Domains (5) summary
    smart00569
    Location:2 → 55
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd00992
    Location:133 → 206
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:351 → 541
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:57 → 108
    L27; L27 domain
    cl17036
    Location:233 → 293
    SH3; Src Homology 3 domain superfamily

  6. XM_015133854.2 → XP_014989340.1  MAGUK p55 subfamily member 6 isoform X1

    UniProtKB/TrEMBL
    A0A1D5R1Q9, F6W428
    Conserved Domains (5) summary
    smart00569
    Location:2 → 55
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd00992
    Location:133 → 206
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:351 → 541
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:57 → 108
    L27; L27 domain
    cl17036
    Location:233 → 293
    SH3; Src Homology 3 domain superfamily

  7. XM_015133850.2 → XP_014989336.1  MAGUK p55 subfamily member 6 isoform X1

    UniProtKB/TrEMBL
    A0A1D5R1Q9, F6W428
    Conserved Domains (5) summary
    smart00569
    Location:2 → 55
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd00992
    Location:133 → 206
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:351 → 541
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:57 → 108
    L27; L27 domain
    cl17036
    Location:233 → 293
    SH3; Src Homology 3 domain superfamily

  8. XM_015133852.2 → XP_014989338.1  MAGUK p55 subfamily member 6 isoform X1

    UniProtKB/TrEMBL
    A0A1D5R1Q9, F6W428
    Conserved Domains (5) summary
    smart00569
    Location:2 → 55
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd00992
    Location:133 → 206
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:351 → 541
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:57 → 108
    L27; L27 domain
    cl17036
    Location:233 → 293
    SH3; Src Homology 3 domain superfamily

  9. XM_028844892.1 → XP_028700725.1  MAGUK p55 subfamily member 6 isoform X1

    UniProtKB/TrEMBL
    A0A1D5R1Q9, F6W428
    Conserved Domains (5) summary
    smart00569
    Location:2 → 55
    L27; domain in receptor targeting proteins Lin-2 and Lin-7
    cd00992
    Location:133 → 206
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:351 → 541
    Guanylate_kin; Guanylate kinase
    pfam02828
    Location:57 → 108
    L27; L27 domain
    cl17036
    Location:233 → 293
    SH3; Src Homology 3 domain superfamily
Nucleotide Protein
Heading Accession and Version

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