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MMP8 matrix metallopeptidase 8 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 703536, updated on 17-Aug-2024

Summary

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Official Symbol
MMP8provided by VGNC
Official Full Name
matrix metallopeptidase 8provided by VGNC
Primary source
VGNC:VGNC:74902
See related
Ensembl:ENSMMUG00000004489
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See MMP8 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
11
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (95993992..96007051, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (95626145..95639055, complement)

Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene matrix metallopeptidase 20 Neighboring gene endogenous retrovirus group K member 7 Env polyprotein-like Neighboring gene matrix metallopeptidase 27 Neighboring gene matrix metallopeptidase 10 Neighboring gene matrix metallopeptidase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in collagen catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in extracellular matrix organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
neutrophil collagenase
Names
matrix metallopeptidase 8 (neutrophil collagenase)
XP_014971041.1
XP_014971042.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041767.1 Reference Mmul_10 Primary Assembly

    Range
    95993992..96007051 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015115555.2 → XP_014971041.1  neutrophil collagenase isoform X1

    UniProtKB/TrEMBL
    G7NB38
    Conserved Domains (4) summary
    cd00094
    Location:285 → 473
    HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
    cd04278
    Location:116 → 271
    ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
    pfam00413
    Location:116 → 271
    Peptidase_M10; Matrixin
    pfam01471
    Location:45 → 95
    PG_binding_1; Putative peptidoglycan binding domain

  2. XM_015115556.2 → XP_014971042.1  neutrophil collagenase isoform X2

    UniProtKB/TrEMBL
    A0A5F8A8W4, G7NB38
    Related
    ENSMMUP00000073817.1, ENSMMUT00000104322.1
    Conserved Domains (4) summary
    cd00094
    Location:276 → 464
    HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
    cd04278
    Location:107 → 262
    ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
    pfam00413
    Location:107 → 262
    Peptidase_M10; Matrixin
    pfam01471
    Location:28 → 86
    PG_binding_1; Putative peptidoglycan binding domain
Nucleotide Protein
Heading Accession and Version

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