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HES2 hes family bHLH transcription factor 2 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 703404, updated on 17-Aug-2024

Summary

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Official Symbol
HES2provided by VGNC
Official Full Name
hes family bHLH transcription factor 2provided by VGNC
Primary source
VGNC:VGNC:73174
See related
Ensembl:ENSMMUG00000022882
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See HES2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
4
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (218101443..218106135)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (5554258..5558975, complement)

Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene TNF receptor superfamily member 25 Neighboring gene espin Neighboring gene acyl-CoA thioesterase 7 Neighboring gene G protein-coupled receptor 153

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in anterior/posterior pattern specification IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of neurogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
transcription factor HES-2
Names
hairy and enhancer of split 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041754.1 Reference Mmul_10 Primary Assembly

    Range
    218101443..218106135
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001092640.4 → XP_001092640.1  transcription factor HES-2

    See identical proteins and their annotated locations for XP_001092640.1

    UniProtKB/TrEMBL
    A0A1D5R8B9
    Related
    ENSMMUP00000056559.1, ENSMMUT00000078976.2
    Conserved Domains (2) summary
    smart00511
    Location:84 → 127
    ORANGE; Orange domain
    cd00083
    Location:12 → 70
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
Nucleotide Protein
Heading Accession and Version

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Molecular Biology Databases
Research Materials