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DRP2 dystrophin related protein 2 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 702655, updated on 17-Aug-2024

Summary

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Official Symbol
DRP2provided by VGNC
Official Full Name
dystrophin related protein 2provided by VGNC
Primary source
VGNC:VGNC:71994
Locus tag
EGK_20738
See related
Ensembl:ENSMMUG00000021579
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See DRP2 in Genome Data Viewer
Location:
chromosome: X
Exon count:
23
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) X NC_041774.1 (98029409..98073524)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) X NC_027913.1 (95409627..95453610)

Chromosome X - NC_041774.1Genomic Context describing neighboring genes Neighboring gene 14-3-3 protein theta pseudogene Neighboring gene riboflavin kinase pseudogene Neighboring gene TATA-box binding protein associated factor 7 like Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in synaptic signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dystrophin-related protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001266215.2 → NP_001253144.1  dystrophin-related protein 2

    See identical proteins and their annotated locations for NP_001253144.1

    Status: PROVISIONAL

    Source sequence(s)
    JV565013
    UniProtKB/TrEMBL
    A0A5F8A0T9, A0A663DDW0, A0A8J8YK80, F7ECU3, G7NSG8
    Related
    ENSMMUP00000028417.3, ENSMMUT00000030367.4
    Conserved Domains (4) summary
    cd00176
    Location:111 → 339
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd00201
    Location:357 → 385
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd02334
    Location:608 → 656
    ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
    cd16248
    Location:422 → 583
    EFh_DRP-2; EF-hand-like motif found in dystrophin-related protein 2 (DRP-2)

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041774.1 Reference Mmul_10 Primary Assembly

    Range
    98029409..98073524
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015127779.2 → XP_014983265.1  dystrophin-related protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A5F8A0T9, A0A663DDW0, A0A8J8YK80, F7ECU3, G7NSG8
    Related
    ENSMMUP00000071525.1, ENSMMUT00000104672.1
    Conserved Domains (4) summary
    cd00176
    Location:111 → 339
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd00201
    Location:357 → 385
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd02334
    Location:608 → 656
    ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
    cd16248
    Location:422 → 583
    EFh_DRP-2; EF-hand-like motif found in dystrophin-related protein 2 (DRP-2)

  2. XM_015127780.2 → XP_014983266.1  dystrophin-related protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A5F8A0T9, F7ECT8
    Related
    ENSMMUP00000028418.4, ENSMMUT00000030368.4
    Conserved Domains (4) summary
    cd00176
    Location:111 → 339
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd00201
    Location:357 → 385
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd02334
    Location:608 → 656
    ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
    cd16248
    Location:422 → 583
    EFh_DRP-2; EF-hand-like motif found in dystrophin-related protein 2 (DRP-2)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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