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PAK6 p21 (RAC1) activated kinase 6 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 701589, updated on 17-Aug-2024

Summary

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Official Symbol
PAK6provided by VGNC
Official Full Name
p21 (RAC1) activated kinase 6provided by VGNC
Primary source
VGNC:VGNC:99207
Locus tag
EGK_17355
See related
Ensembl:ENSMMUG00000020534
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See PAK6 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
15
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (16647502..16687158)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (16539690..16600828)

Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene Bcl2 modifying factor Neighboring gene BUB1 mitotic checkpoint serine/threonine kinase B Neighboring gene uncharacterized LOC114679380 Neighboring gene PAK6 antisense RNA 1 Neighboring gene ankyrin repeat domain 63 Neighboring gene phospholipase C beta 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase PAK 6
Names
p21(CDKN1A)-activated kinase 6
NP_001248582.1
XP_014997344.1
XP_014997346.1
XP_014997347.1
XP_014997349.1
XP_014997350.1
XP_028706114.1
XP_028706115.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001261653.1 → NP_001248582.1  serine/threonine-protein kinase PAK 6

    See identical proteins and their annotated locations for NP_001248582.1

    Status: PROVISIONAL

    Source sequence(s)
    JV047705
    UniProtKB/TrEMBL
    A0A8J8Y883, F6TWF0, F7D8F1, G7MWM9
    Related
    ENSMMUP00000033842.1, ENSMMUT00000040817.3
    Conserved Domains (2) summary
    cd06659
    Location:385 → 681
    STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6
    pfam00786
    Location:11 → 63
    PBD; P21-Rho-binding domain

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041760.1 Reference Mmul_10 Primary Assembly

    Range
    16647502..16687158
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015141861.2 → XP_014997347.1  serine/threonine-protein kinase PAK 6 isoform X2

    UniProtKB/TrEMBL
    A0A8J8Y883, F6TWF0, F7D8F1, G7MWM9
    Related
    ENSMMUP00000027042.4, ENSMMUT00000028897.4
    Conserved Domains (2) summary
    cd06659
    Location:385 → 681
    STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6
    pfam00786
    Location:11 → 63
    PBD; P21-Rho-binding domain

  2. XM_015141860.2 → XP_014997346.1  serine/threonine-protein kinase PAK 6 isoform X2

    UniProtKB/TrEMBL
    A0A8J8Y883, F6TWF0, F7D8F1, G7MWM9
    Conserved Domains (2) summary
    cd06659
    Location:385 → 681
    STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6
    pfam00786
    Location:11 → 63
    PBD; P21-Rho-binding domain

  3. XM_015141863.1 → XP_014997349.1  serine/threonine-protein kinase PAK 6 isoform X2

    UniProtKB/TrEMBL
    A0A8J8Y883, F6TWF0, F7D8F1, G7MWM9
    Conserved Domains (2) summary
    cd06659
    Location:385 → 681
    STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6
    pfam00786
    Location:11 → 63
    PBD; P21-Rho-binding domain

  4. XM_028850281.1 → XP_028706114.1  serine/threonine-protein kinase PAK 6 isoform X2

    UniProtKB/TrEMBL
    A0A8J8Y883, F6TWF0, F7D8F1, G7MWM9
    Conserved Domains (2) summary
    cd06659
    Location:385 → 681
    STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6
    pfam00786
    Location:11 → 63
    PBD; P21-Rho-binding domain

  5. XM_028850282.1 → XP_028706115.1  serine/threonine-protein kinase PAK 6 isoform X2

    UniProtKB/TrEMBL
    A0A8J8Y883, F6TWF0, F7D8F1, G7MWM9
    Conserved Domains (2) summary
    cd06659
    Location:385 → 681
    STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6
    pfam00786
    Location:11 → 63
    PBD; P21-Rho-binding domain

  6. XM_015141858.2 → XP_014997344.1  serine/threonine-protein kinase PAK 6 isoform X1

    Conserved Domains (3) summary
    smart00220
    Location:436 → 682
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd06659
    Location:409 → 705
    STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6
    pfam00786
    Location:35 → 87
    PBD; P21-Rho-binding domain

  7. XM_015141864.2 → XP_014997350.1  serine/threonine-protein kinase PAK 6 isoform X2

    UniProtKB/TrEMBL
    A0A8J8Y883, F6TWF0, F7D8F1, G7MWM9
    Conserved Domains (2) summary
    cd06659
    Location:385 → 681
    STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6
    pfam00786
    Location:11 → 63
    PBD; P21-Rho-binding domain
Nucleotide Protein
Heading Accession and Version

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