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GCKR glucokinase regulator [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 701431, updated on 17-Aug-2024

Summary

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Official Symbol
GCKRprovided by VGNC
Official Full Name
glucokinase regulatorprovided by VGNC
Primary source
VGNC:VGNC:72902
Locus tag
EGK_05172
See related
Ensembl:ENSMMUG00000005102
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See GCKR in Genome Data Viewer
Location:
chromosome: 13
Exon count:
20
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 13 NC_041766.1 (81431611..81454787, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 13 NC_027905.1 (27793304..27816477)

Chromosome 13 - NC_041766.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 512 Neighboring gene SPATA31 subfamily H member 1 Neighboring gene uncharacterized LOC114671747 Neighboring gene fibronectin type III domain containing 4 Neighboring gene intraflagellar transport 172 Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables enzyme binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables enzyme inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fructose-6-phosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in carbohydrate derivative metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glucose homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of glucokinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to fructose IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
glucokinase regulatory protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041766.1 Reference Mmul_10 Primary Assembly

    Range
    81431611..81454787 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001098190.4 → XP_001098190.2  glucokinase regulatory protein isoform X1

    UniProtKB/TrEMBL
    F7BYJ8, G7N9P7
    Related
    ENSMMUP00000006765.3, ENSMMUT00000007199.4
    Conserved Domains (2) summary
    PRK05441
    Location:30 → 273
    murQ; N-acetylmuramic acid-6-phosphate etherase; Reviewed
    cl00389
    Location:293 → 541
    SIS; SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars.

  2. XM_028831833.1 → XP_028687666.1  glucokinase regulatory protein isoform X2

    Conserved Domains (2) summary
    PRK05441
    Location:30 → 273
    murQ; N-acetylmuramic acid-6-phosphate etherase; Reviewed
    cl00389
    Location:293 → 366
    SIS; SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars.
Nucleotide Protein
Heading Accession and Version

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