U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

SHMT1 serine hydroxymethyltransferase 1 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 701186, updated on 17-Aug-2024

Summary

Go to the top of the page Help
Official Symbol
SHMT1provided by VGNC
Official Full Name
serine hydroxymethyltransferase 1provided by VGNC
Primary source
VGNC:VGNC:103864
See related
Ensembl:ENSMMUG00000013535
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See SHMT1 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
14
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (18175976..18213528, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (18503125..18540753, complement)

Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene DNA topoisomerase III alpha Neighboring gene SMCR8-C9orf72 complex subunit Neighboring gene uncharacterized LOC106993915 Neighboring gene uncharacterized LOC106993916 Neighboring gene coactosin-like protein pseudogene

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cobalt ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables glycine hydroxymethyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mRNA 5'-UTR binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mRNA regulatory element binding translation repressor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in L-serine catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to leukemia inhibitory factor IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in folic acid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glycine biosynthetic process from serine IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein homotetramerization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in purine nucleobase biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tetrahydrofolate interconversion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
serine hydroxymethyltransferase, cytosolic
NP_001244360.1
XP_014974168.1
XP_014974169.1
XP_014974170.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001257431.1 → NP_001244360.1  serine hydroxymethyltransferase, cytosolic

    See identical proteins and their annotated locations for NP_001244360.1

    Status: PROVISIONAL

    Source sequence(s)
    JU335936
    UniProtKB/TrEMBL
    F6WIE8, F7FV99, G7NJ32
    Conserved Domains (2) summary
    PLN03226
    Location:24 → 480
    PLN03226; serine hydroxymethyltransferase; Provisional
    pfam00464
    Location:26 → 425
    SHMT; Serine hydroxymethyltransferase

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041769.1 Reference Mmul_10 Primary Assembly

    Range
    18175976..18213528 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015118682.2 → XP_014974168.1  serine hydroxymethyltransferase, cytosolic isoform X1

    UniProtKB/TrEMBL
    F6WIE8, F7FV99, G7NJ32
    Related
    ENSMMUP00000017801.4, ENSMMUT00000019005.4
    Conserved Domains (2) summary
    PLN03226
    Location:24 → 480
    PLN03226; serine hydroxymethyltransferase; Provisional
    pfam00464
    Location:26 → 425
    SHMT; Serine hydroxymethyltransferase

  2. XM_015118684.2 → XP_014974170.1  serine hydroxymethyltransferase, cytosolic isoform X1

    UniProtKB/TrEMBL
    F6WIE8, F7FV99, G7NJ32
    Conserved Domains (2) summary
    PLN03226
    Location:24 → 480
    PLN03226; serine hydroxymethyltransferase; Provisional
    pfam00464
    Location:26 → 425
    SHMT; Serine hydroxymethyltransferase

  3. XM_015118683.2 → XP_014974169.1  serine hydroxymethyltransferase, cytosolic isoform X1

    UniProtKB/TrEMBL
    F6WIE8, F7FV99, G7NJ32
    Conserved Domains (2) summary
    PLN03226
    Location:24 → 480
    PLN03226; serine hydroxymethyltransferase; Provisional
    pfam00464
    Location:26 → 425
    SHMT; Serine hydroxymethyltransferase
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials