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ARHGEF10L Rho guanine nucleotide exchange factor 10 like [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 701164, updated on 17-Aug-2024

Summary

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Official Symbol
ARHGEF10Lprovided by VGNC
Official Full Name
Rho guanine nucleotide exchange factor 10 likeprovided by VGNC
Primary source
VGNC:VGNC:69908
See related
Ensembl:ENSMMUG00000010849
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See ARHGEF10L in Genome Data Viewer
Location:
chromosome: 1
Exon count:
33
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (207049318..207227740, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (16243960..16423462)

Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene immunoglobin superfamily member 21 Neighboring gene actin like 8 Neighboring gene uncharacterized LOC114673995 Neighboring gene regulator of chromosome condensation 2 Neighboring gene peptidyl arginine deiminase 6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in SREBP signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of stress fiber assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
rho guanine nucleotide exchange factor 10-like protein
Names
Rho guanine nucleotide exchange factor (GEF) 10-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041754.1 Reference Mmul_10 Primary Assembly

    Range
    207049318..207227740 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001089828.4 → XP_001089828.2  rho guanine nucleotide exchange factor 10-like protein isoform X11

    UniProtKB/TrEMBL
    F7G3F5, I0FT05
    Related
    ENSMMUP00000014221.4, ENSMMUT00000015177.4
    Conserved Domains (2) summary
    smart00325
    Location:279 → 461
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    PRK07764
    Location:2 → 147
    PRK07764; DNA polymerase III subunits gamma and tau; Validated

  2. XM_001089707.4 → XP_001089707.2  rho guanine nucleotide exchange factor 10-like protein isoform X10

    UniProtKB/TrEMBL
    F7G3F1, F7G3F5
    Related
    ENSMMUP00000014222.4, ENSMMUT00000015178.4
    Conserved Domains (2) summary
    smart00325
    Location:279 → 461
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    PRK07764
    Location:2 → 147
    PRK07764; DNA polymerase III subunits gamma and tau; Validated

  3. XM_015125089.2 → XP_014980575.2  rho guanine nucleotide exchange factor 10-like protein isoform X12

    UniProtKB/TrEMBL
    A0A5F7ZAY6, F7G3F5
    Related
    ENSMMUP00000062726.1, ENSMMUT00000083537.1
    Conserved Domains (1) summary
    cd00160
    Location:95 → 279
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

  4. XM_028838907.1 → XP_028694740.1  rho guanine nucleotide exchange factor 10-like protein isoform X2

    UniProtKB/TrEMBL
    G7MH60
    Related
    ENSMMUP00000069981.1, ENSMMUT00000085171.1
    Conserved Domains (2) summary
    PRK07764
    Location:2 → 147
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd00160
    Location:318 → 502
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

  5. XM_028838896.1 → XP_028694729.1  rho guanine nucleotide exchange factor 10-like protein isoform X1

    UniProtKB/TrEMBL
    G7MH60
    Conserved Domains (2) summary
    PRK07764
    Location:2 → 167
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd00160
    Location:319 → 503
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

  6. XM_028838891.1 → XP_028694724.1  rho guanine nucleotide exchange factor 10-like protein isoform X1

    UniProtKB/TrEMBL
    G7MH60
    Conserved Domains (2) summary
    PRK07764
    Location:2 → 167
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd00160
    Location:319 → 503
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

  7. XM_028838899.1 → XP_028694732.1  rho guanine nucleotide exchange factor 10-like protein isoform X1

    UniProtKB/TrEMBL
    G7MH60
    Conserved Domains (2) summary
    PRK07764
    Location:2 → 167
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd00160
    Location:319 → 503
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

  8. XM_028838902.1 → XP_028694735.1  rho guanine nucleotide exchange factor 10-like protein isoform X2

    UniProtKB/TrEMBL
    G7MH60
    Conserved Domains (2) summary
    PRK07764
    Location:2 → 147
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd00160
    Location:318 → 502
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

  9. XM_028838935.1 → XP_028694768.1  rho guanine nucleotide exchange factor 10-like protein isoform X8

    UniProtKB/TrEMBL
    F7G3F5
    Conserved Domains (2) summary
    smart00325
    Location:283 → 465
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    PRK07764
    Location:2 → 167
    PRK07764; DNA polymerase III subunits gamma and tau; Validated

  10. XM_028838921.1 → XP_028694754.1  rho guanine nucleotide exchange factor 10-like protein isoform X5

    UniProtKB/TrEMBL
    G7MH60
    Conserved Domains (2) summary
    PRK07764
    Location:2 → 167
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd00160
    Location:319 → 503
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

  11. XM_015124833.2 → XP_014980319.2  rho guanine nucleotide exchange factor 10-like protein isoform X7

    UniProtKB/TrEMBL
    A0A5F7ZPL8, G7MH60
    Related
    ENSMMUP00000067126.1, ENSMMUT00000106163.1
    Conserved Domains (2) summary
    PRK07764
    Location:2 → 147
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd00160
    Location:315 → 499
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

  12. XM_015124905.2 → XP_014980391.2  rho guanine nucleotide exchange factor 10-like protein isoform X9

    UniProtKB/TrEMBL
    F7G3F5
    Conserved Domains (2) summary
    smart00325
    Location:280 → 462
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    PRK07764
    Location:2 → 167
    PRK07764; DNA polymerase III subunits gamma and tau; Validated

  13. XM_015124800.2 → XP_014980286.2  rho guanine nucleotide exchange factor 10-like protein isoform X6

    UniProtKB/TrEMBL
    G7MH60
    Conserved Domains (2) summary
    PRK07764
    Location:2 → 167
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd00160
    Location:316 → 500
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

  14. XM_015124528.2 → XP_014980014.2  rho guanine nucleotide exchange factor 10-like protein isoform X3

    UniProtKB/TrEMBL
    G7MH60
    Conserved Domains (2) summary
    PRK07764
    Location:2 → 167
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd00160
    Location:316 → 500
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

  15. XM_028838912.1 → XP_028694745.1  rho guanine nucleotide exchange factor 10-like protein isoform X4

    UniProtKB/TrEMBL
    F7G3F9, G7MH60
    Related
    ENSMMUP00000014220.4, ENSMMUT00000015176.4
    Conserved Domains (2) summary
    PRK07764
    Location:2 → 147
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    cd00160
    Location:315 → 499
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

  16. XM_028838964.1 → XP_028694797.1  rho guanine nucleotide exchange factor 10-like protein isoform X14

    UniProtKB/TrEMBL
    F7G3F5
    Conserved Domains (1) summary
    cd00160
    Location:78 → 262
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.

  17. XM_015125156.2 → XP_014980642.2  rho guanine nucleotide exchange factor 10-like protein isoform X13

    UniProtKB/TrEMBL
    F7G3F5
    Conserved Domains (1) summary
    cd00160
    Location:95 → 279
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
Nucleotide Protein
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