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PTPRF protein tyrosine phosphatase receptor type F [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 701160, updated on 17-Aug-2024

Summary

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Official Symbol
PTPRFprovided by VGNC
Official Full Name
protein tyrosine phosphatase receptor type Fprovided by VGNC
Primary source
VGNC:VGNC:76615
See related
Ensembl:ENSMMUG00000012477
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See PTPRF in Genome Data Viewer
Location:
chromosome: 1
Exon count:
38
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (180841651..180935007, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (43021490..43115787)

Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene ST3 beta-galactoside alpha-2,3-sialyltransferase 3 Neighboring gene U6 spliceosomal RNA Neighboring gene lysine demethylase 4A Neighboring gene SZT2 subunit of KICSTOR complex Neighboring gene hydroxypyruvate isomerase (putative) Neighboring gene mediator complex subunit 8

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Form deprivation modulates retinal neurogenesis in primate experimental myopia. Tkatchenko AV, et al. Proc Natl Acad Sci U S A, 2006 Mar 21. PMID 16537371, Free PMC Article
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
receptor-type tyrosine-protein phosphatase F
XP_014992970.1
XP_014992973.1
XP_014992979.1
XP_014992986.1
XP_014992989.1
XP_014992992.1
XP_014993000.1
XP_014993010.1
XP_014993014.1
XP_014993018.1
XP_014993024.1
XP_014993029.1
XP_014993033.1
XP_014993039.1
XP_014993044.1
XP_014993053.1
XP_028690619.1
XP_028690623.1
XP_028690628.1
XP_028690634.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041754.1 Reference Mmul_10 Primary Assembly

    Range
    180841651..180935007 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028834801.1 → XP_028690634.1  receptor-type tyrosine-protein phosphatase F isoform X17

    UniProtKB/TrEMBL
    A0A5F7Z8Q2
    Conserved Domains (7) summary
    cd00063
    Location:319 → 408
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14626
    Location:1031 → 1306
    R-PTPc-F-1; catalytic domain of receptor-type tyrosine-protein phosphatase F, repeat 1
    cd14629
    Location:1308 → 1598
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain
    cd00096
    Location:33 → 36
    Ig; Ig strand A [structural motif]
    cd05738
    Location:136 → 226
    IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
    cd05739
    Location:235 → 316
    IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

  2. XM_028834795.1 → XP_028690628.1  receptor-type tyrosine-protein phosphatase F isoform X16

    UniProtKB/TrEMBL
    A0A5F7Z8Q2
    Conserved Domains (7) summary
    cd00063
    Location:319 → 408
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14626
    Location:1051 → 1326
    R-PTPc-F-1; catalytic domain of receptor-type tyrosine-protein phosphatase F, repeat 1
    cd14629
    Location:1328 → 1618
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain
    cd00096
    Location:33 → 36
    Ig; Ig strand A [structural motif]
    cd05738
    Location:136 → 226
    IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
    cd05739
    Location:235 → 316
    IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

  3. XM_015137538.2 → XP_014993024.1  receptor-type tyrosine-protein phosphatase F isoform X9

    UniProtKB/TrEMBL
    F7H285, G7MGL5
    Related
    ENSMMUP00000016385.4, ENSMMUT00000017495.4
    Conserved Domains (8) summary
    cd00096
    Location:50 → 121
    Ig; Immunoglobulin domain
    cd05738
    Location:152 → 226
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:246 → 314
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:1342 → 1597
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:238 → 315
    IG_like; Immunoglobulin like
    cd00047
    Location:1368 → 1597
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:319 → 408
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain

  4. XM_015137553.2 → XP_014993039.1  receptor-type tyrosine-protein phosphatase F isoform X12

    UniProtKB/TrEMBL
    A0A5F7Z8Q2
    Conserved Domains (8) summary
    cd00096
    Location:50 → 121
    Ig; Immunoglobulin domain
    cd05738
    Location:152 → 226
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:246 → 314
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:1240 → 1495
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:238 → 315
    IG_like; Immunoglobulin like
    cd00047
    Location:1266 → 1495
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:319 → 408
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain

  5. XM_015137514.2 → XP_014993000.1  receptor-type tyrosine-protein phosphatase F isoform X5

    UniProtKB/TrEMBL
    A0A5F7ZLB0, F7H285
    Related
    ENSMMUP00000065413.1, ENSMMUT00000096675.1
    Conserved Domains (8) summary
    cd00096
    Location:50 → 121
    Ig; Immunoglobulin domain
    cd05738
    Location:152 → 226
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:246 → 314
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:1362 → 1617
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:238 → 315
    IG_like; Immunoglobulin like
    cd00047
    Location:1388 → 1617
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:319 → 408
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain

  6. XM_015137503.2 → XP_014992989.1  receptor-type tyrosine-protein phosphatase F isoform X3

    UniProtKB/TrEMBL
    A0A1D5REK9
    Conserved Domains (8) summary
    cd00096
    Location:50 → 121
    Ig; Immunoglobulin domain
    cd05738
    Location:152 → 226
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:250 → 318
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:1366 → 1621
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:242 → 319
    IG_like; Immunoglobulin like
    cd00047
    Location:1392 → 1621
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:323 → 412
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain

  7. XM_015137500.2 → XP_014992986.1  receptor-type tyrosine-protein phosphatase F isoform X2

    UniProtKB/TrEMBL
    F7H285
    Conserved Domains (8) summary
    cd00096
    Location:50 → 121
    Ig; Immunoglobulin domain
    cd05738
    Location:152 → 232
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:252 → 320
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:1368 → 1623
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:244 → 321
    IG_like; Immunoglobulin like
    cd00047
    Location:1394 → 1623
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:325 → 414
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain

  8. XM_015137547.2 → XP_014993033.1  receptor-type tyrosine-protein phosphatase F isoform X11

    UniProtKB/TrEMBL
    A0A5F7Z8Q2
    Conserved Domains (8) summary
    cd00096
    Location:50 → 121
    Ig; Immunoglobulin domain
    cd05738
    Location:152 → 232
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:256 → 324
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:1261 → 1516
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:248 → 325
    IG_like; Immunoglobulin like
    cd00047
    Location:1287 → 1516
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:329 → 418
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain

  9. XM_015137543.2 → XP_014993029.1  receptor-type tyrosine-protein phosphatase F isoform X10

    UniProtKB/TrEMBL
    A0A5F7Z8Q2
    Related
    ENSMMUP00000061914.1, ENSMMUT00000103352.1
    Conserved Domains (8) summary
    cd00096
    Location:50 → 121
    Ig; Immunoglobulin domain
    cd05738
    Location:152 → 232
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:256 → 324
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:1270 → 1525
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:248 → 325
    IG_like; Immunoglobulin like
    cd00047
    Location:1296 → 1525
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:329 → 418
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain

  10. XM_015137528.2 → XP_014993014.1  receptor-type tyrosine-protein phosphatase F isoform X7

    UniProtKB/TrEMBL
    A0A1D5REK9
    Conserved Domains (8) summary
    cd00096
    Location:50 → 121
    Ig; Immunoglobulin domain
    cd05738
    Location:152 → 232
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:256 → 324
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:1352 → 1607
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:248 → 325
    IG_like; Immunoglobulin like
    cd00047
    Location:1378 → 1607
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:329 → 418
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain

  11. XM_015137506.2 → XP_014992992.1  receptor-type tyrosine-protein phosphatase F isoform X4

    UniProtKB/TrEMBL
    A0A1D5REK9
    Related
    ENSMMUP00000058752.2, ENSMMUT00000072065.2
    Conserved Domains (8) summary
    cd00096
    Location:50 → 121
    Ig; Immunoglobulin domain
    cd05738
    Location:152 → 232
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:256 → 324
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:1363 → 1618
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:248 → 325
    IG_like; Immunoglobulin like
    cd00047
    Location:1389 → 1618
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:329 → 418
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain

  12. XM_015137524.2 → XP_014993010.1  receptor-type tyrosine-protein phosphatase F isoform X6

    UniProtKB/TrEMBL
    G7MGL5
    Conserved Domains (8) summary
    cd00096
    Location:50 → 121
    Ig; Immunoglobulin domain
    cd05738
    Location:152 → 232
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:256 → 324
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:1361 → 1616
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:248 → 325
    IG_like; Immunoglobulin like
    cd00047
    Location:1387 → 1616
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:329 → 418
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain

  13. XM_015137484.2 → XP_014992970.1  receptor-type tyrosine-protein phosphatase F isoform X1

    UniProtKB/TrEMBL
    A0A1D5REK9
    Conserved Domains (8) summary
    cd00096
    Location:50 → 121
    Ig; Immunoglobulin domain
    cd05738
    Location:152 → 232
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:256 → 324
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:1372 → 1627
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:248 → 325
    IG_like; Immunoglobulin like
    cd00047
    Location:1398 → 1627
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:329 → 418
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain

  14. XM_015137493.2 → XP_014992979.1  receptor-type tyrosine-protein phosphatase F isoform X1

    UniProtKB/TrEMBL
    A0A1D5REK9
    Conserved Domains (8) summary
    cd00096
    Location:50 → 121
    Ig; Immunoglobulin domain
    cd05738
    Location:152 → 232
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:256 → 324
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:1372 → 1627
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:248 → 325
    IG_like; Immunoglobulin like
    cd00047
    Location:1398 → 1627
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:329 → 418
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain

  15. XM_015137487.2 → XP_014992973.1  receptor-type tyrosine-protein phosphatase F isoform X1

    UniProtKB/TrEMBL
    A0A1D5REK9
    Conserved Domains (8) summary
    cd00096
    Location:50 → 121
    Ig; Immunoglobulin domain
    cd05738
    Location:152 → 232
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:256 → 324
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:1372 → 1627
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:248 → 325
    IG_like; Immunoglobulin like
    cd00047
    Location:1398 → 1627
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:329 → 418
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain

  16. XM_015137567.2 → XP_014993053.1  receptor-type tyrosine-protein phosphatase F isoform X18

    UniProtKB/TrEMBL
    A0A5F8AAF4
    Conserved Domains (7) summary
    cd00063
    Location:323 → 412
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14626
    Location:1157 → 1432
    R-PTPc-F-1; catalytic domain of receptor-type tyrosine-protein phosphatase F, repeat 1
    cd14629
    Location:1434 → 1724
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain
    cd00096
    Location:33 → 36
    Ig; Ig strand A [structural motif]
    cd05738
    Location:136 → 226
    IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
    cd05739
    Location:239 → 320
    IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

  17. XM_015137532.2 → XP_014993018.1  receptor-type tyrosine-protein phosphatase F isoform X8

    UniProtKB/TrEMBL
    G7MGL5
    Related
    ENSMMUP00000074855.1, ENSMMUT00000107220.1
    Conserved Domains (8) summary
    cd00096
    Location:50 → 121
    Ig; Immunoglobulin domain
    cd05738
    Location:152 → 226
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:246 → 314
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:1351 → 1606
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:238 → 315
    IG_like; Immunoglobulin like
    cd00047
    Location:1377 → 1606
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:319 → 408
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain

  18. XM_028834790.1 → XP_028690623.1  receptor-type tyrosine-protein phosphatase F isoform X15

    UniProtKB/TrEMBL
    A0A5F7Z8Q2
    Conserved Domains (7) summary
    cd00063
    Location:325 → 414
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14626
    Location:1057 → 1332
    R-PTPc-F-1; catalytic domain of receptor-type tyrosine-protein phosphatase F, repeat 1
    cd14629
    Location:1334 → 1624
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain
    cd00096
    Location:33 → 36
    Ig; Ig strand A [structural motif]
    cd05738
    Location:136 → 232
    IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
    cd05739
    Location:241 → 322
    IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

  19. XM_028834786.1 → XP_028690619.1  receptor-type tyrosine-protein phosphatase F isoform X14

    UniProtKB/TrEMBL
    A0A5F7Z8Q2
    Conserved Domains (7) summary
    cd00063
    Location:329 → 418
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14626
    Location:1061 → 1336
    R-PTPc-F-1; catalytic domain of receptor-type tyrosine-protein phosphatase F, repeat 1
    cd14629
    Location:1338 → 1628
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain
    cd00096
    Location:33 → 36
    Ig; Ig strand A [structural motif]
    cd05738
    Location:136 → 232
    IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
    cd05739
    Location:245 → 326
    IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains

  20. XM_015137558.2 → XP_014993044.1  receptor-type tyrosine-protein phosphatase F isoform X13

    UniProtKB/TrEMBL
    A0A5F8AAF4
    Related
    ENSMMUP00000079821.1, ENSMMUT00000094181.1
    Conserved Domains (7) summary
    cd00063
    Location:329 → 418
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14626
    Location:1163 → 1438
    R-PTPc-F-1; catalytic domain of receptor-type tyrosine-protein phosphatase F, repeat 1
    cd14629
    Location:1440 → 1730
    R-PTP-F-2; PTP-like domain of receptor-type tyrosine-protein phosphatase F, repeat 2
    pfam07679
    Location:33 → 124
    I-set; Immunoglobulin I-set domain
    cd00096
    Location:33 → 36
    Ig; Ig strand A [structural motif]
    cd05738
    Location:136 → 232
    IgI_2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F; member of the I-set of IgSF domains
    cd05739
    Location:245 → 326
    IgI_3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F (also known as LAR), type IIa; member of the I-set of IgSF domains
Nucleotide Protein
Heading Accession and Version

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