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Igsf23 immunoglobulin superfamily, member 23 [ Mus musculus (house mouse) ]

Gene ID: 70080, updated on 27-Nov-2024

Summary

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Official Symbol
Igsf23provided by MGI
Official Full Name
immunoglobulin superfamily, member 23provided by MGI
Primary source
MGI:MGI:1917330
See related
Ensembl:ENSMUSG00000040498 AllianceGenome:MGI:1917330
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2210010C17Rik
Summary
Predicted to be involved in osteoclast differentiation. Predicted to be located in plasma membrane. Orthologous to human IGSF23 (immunoglobulin superfamily member 23). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in duodenum adult (RPKM 65.3), small intestine adult (RPKM 50.5) and 5 other tissues See more
Orthologs
human all
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Genomic context

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See Igsf23 in Genome Data Viewer
Location:
7 A3; 7 9.95 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (19671230..19687579, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (19937305..19953654, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene poliovirus receptor Neighboring gene ribosomal protein L14 pseudogene Neighboring gene predicted gene 16251 Neighboring gene STARR-seq mESC enhancer starr_18231 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:20517919-20518126 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:20518638-20518747 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:20520941-20521094 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:20525341-20525450 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:20525675-20525828 Neighboring gene ribosomal protein L7A, pseudogene 8 Neighboring gene CEA cell adhesion molecule 20

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities. Liu C, et al. Sci Adv, 2023 May 19. PMID 37196079, Free PMC Article
  2. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in osteoclast differentiation ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
immunoglobulin superfamily member 23

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001364024.1 → NP_001350953.1  immunoglobulin superfamily member 23 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AK033677, AK135657
    Conserved Domains (1) summary
    smart00408
    Location:125 → 174
    IGc2; Immunoglobulin C-2 Type

  2. NM_001364025.1 → NP_001350954.1  immunoglobulin superfamily member 23 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC130530, AC149085
    Consensus CDS
    CCDS90175.1
    UniProtKB/TrEMBL
    A0A140LJ51
    Related
    ENSMUSP00000147077.2, ENSMUST00000208974.2
    Conserved Domains (1) summary
    smart00408
    Location:79 → 128
    IGc2; Immunoglobulin C-2 Type

  3. NM_027308.2 → NP_081584.1  immunoglobulin superfamily member 23 isoform 1 precursor

    See identical proteins and their annotated locations for NP_081584.1

    Status: VALIDATED

    Source sequence(s)
    AK033677
    Consensus CDS
    CCDS52065.1
    UniProtKB/Swiss-Prot
    B2RTN2
    Related
    ENSMUSP00000047914.7, ENSMUST00000043440.8
    Conserved Domains (1) summary
    smart00408
    Location:117 → 166
    IGc2; Immunoglobulin C-2 Type

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    19671230..19687579 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006540355.4 → XP_006540418.1  immunoglobulin superfamily member 23 isoform X2

    Conserved Domains (1) summary
    smart00408
    Location:47 → 96
    IGc2; Immunoglobulin C-2 Type

  2. XM_006540354.4 → XP_006540417.1  immunoglobulin superfamily member 23 isoform X1

    Conserved Domains (1) summary
    smart00408
    Location:117 → 166
    IGc2; Immunoglobulin C-2 Type
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
B2RTN2.1 GenPept UniProtKB/Swiss-Prot:B2RTN2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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