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SESN1 sestrin 1 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 700232, updated on 17-Aug-2024

Summary

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Official Symbol
SESN1provided by VGNC
Official Full Name
sestrin 1provided by VGNC
Primary source
VGNC:VGNC:77289
Locus tag
EGK_15463
See related
Ensembl:ENSMMUG00000018232
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See SESN1 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
12
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (12675435..12782237, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (158826926..158934016)

Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L37a-like Neighboring gene 40S ribosomal protein S12 pseudogene Neighboring gene armadillo repeat containing 2 Neighboring gene U6 spliceosomal RNA Neighboring gene centrosomal protein 57 like 1 Neighboring gene putative uncharacterized protein C6orf183

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables L-leucine binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidoreductase activity, acting on peroxide as acceptor IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to L-leucine IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to leucine starvation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of TORC1 signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of macroautophagy IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of response to reactive oxygen species IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sestrin-1
XP_014993094.1
XP_014993095.1
XP_014993097.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041757.1 Reference Mmul_10 Primary Assembly

    Range
    12675435..12782237 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015137608.2 → XP_014993094.1  sestrin-1 isoform X1

    UniProtKB/TrEMBL
    A0A5S6RBQ4, A0A8J8Y4R1, F7E0H5, G7MQY5, H9F854
    Related
    ENSMMUP00000023971.4, ENSMMUT00000025624.4
    Conserved Domains (1) summary
    pfam04636
    Location:106 → 550
    PA26; PA26 p53-induced protein (sestrin)

  2. XM_015137609.2 → XP_014993095.1  sestrin-1 isoform X1

    UniProtKB/TrEMBL
    A0A5S6RBQ4, A0A8J8Y4R1, F7E0H5, G7MQY5, H9F854
    Related
    ENSMMUP00000077453.1, ENSMMUT00000092716.1
    Conserved Domains (1) summary
    pfam04636
    Location:106 → 550
    PA26; PA26 p53-induced protein (sestrin)

  3. XM_015137611.2 → XP_014993097.1  sestrin-1 isoform X2

    UniProtKB/TrEMBL
    A0A5F8AL42, F7D7D8
    Related
    ENSMMUP00000032977.1, ENSMMUT00000039917.3
    Conserved Domains (1) summary
    pfam04636
    Location:47 → 491
    PA26; PA26 p53-induced protein (sestrin)
Nucleotide Protein
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