FOXO1 forkhead box O1 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: FOXO1provided by VGNC
Official Full Name: forkhead box O1provided by VGNC
Primary source: VGNC:VGNC:72703
See related: Ensembl:ENSMMUG00000030780
Gene type: protein coding
RefSeq status: MODEL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as: FOXO1A
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 17

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	17	NC_041770.1 (19245471..19357233, complement)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	17	NC_027909.1 (19866122..19977589, complement)

Chromosome 17 - NC_041770.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

FOXO1, 3, and 4 as well as their upstream regulator, AKT/p-AKT, was examined in rhesus macaque ovaries of three developmental stages: fetal, prepubertal, and adult
Title: Characterization of FOXO1, 3 and 4 transcription factors in ovaries of fetal, prepubertal and adult rhesus macaques.

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General gene information

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Markers

RH78770 (e-PCR)
- UniSTS:59152

RH119158 (e-PCR)
- UniSTS:139049

SHGC-82099 (e-PCR)
- UniSTS:103025

G64954 (e-PCR)
- UniSTS:164987

RH74854 (e-PCR)
- UniSTS:92039

RH46975 (e-PCR)
- UniSTS:64724

D13S1162 (e-PCR)
- UniSTS:78564

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in insulin receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: forkhead box protein O1

Names: forkhead box O1A

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041770.1 Reference Mmul_10 Primary Assembly

Range

19245471..19357233 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_001088437.4 → XP_001088437.2 forkhead box protein O1

UniProtKB/TrEMBL

F6ZVZ0

Related

ENSMMUP00000036378.1, ENSMMUT00000043379.3

Conserved Domains (3) summary

cd00059
Location:160 → 240

FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...

pfam16675
Location:423 → 500

FOXO_KIX_bdg; KIX-binding domain of forkhead box O, CR2

pfam16676
Location:597 → 633

FOXO-TAD; Transactivation domain of FOXO protein family