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IRAK1 interleukin 1 receptor associated kinase 1 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 699919, updated on 17-Aug-2024

Summary

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Official Symbol
IRAK1provided by VGNC
Official Full Name
interleukin 1 receptor associated kinase 1provided by VGNC
Primary source
VGNC:VGNC:73757
See related
Ensembl:ENSMMUG00000018703
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See IRAK1 in Genome Data Viewer
Location:
chromosome: X
Exon count:
14
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) X NC_041774.1 (150001510..150011622, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) X NC_027913.1 (147488375..147498490, complement)

Chromosome X - NC_041774.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106995372 Neighboring gene host cell factor C1 Neighboring gene transmembrane protein 187 Neighboring gene methyl-CpG binding protein 2 Neighboring gene opsin 1, long wave sensitive

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Divergent TLR7 and TLR9 signaling and type I interferon production distinguish pathogenic and nonpathogenic AIDS virus infections. Mandl JN, et al. Nat Med, 2008 Oct. PMID 18806803
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in interleukin-1-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of NF-kappaB transcription factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
interleukin-1 receptor-associated kinase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041774.1 Reference Mmul_10 Primary Assembly

    Range
    150001510..150011622 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015128547.2 → XP_014984033.2  interleukin-1 receptor-associated kinase 1

    UniProtKB/TrEMBL
    F6WX15, I2CWY8
    Related
    ENSMMUP00000046892.2, ENSMMUT00000060061.2
    Conserved Domains (2) summary
    cd08794
    Location:17 → 100
    Death_IRAK1; Death domain of Interleukin 1 Receptor Associated Kinase-1
    cd14159
    Location:218 → 517
    STKc_IRAK1; Catalytic domain of the Serine/Threonine kinase, Interleukin-1 Receptor Associated Kinase 1
Nucleotide Protein
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