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PARD6A par-6 family cell polarity regulator alpha [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 699351, updated on 17-Aug-2024

Summary

Official Symbol
PARD6Aprovided by VGNC
Official Full Name
par-6 family cell polarity regulator alphaprovided by VGNC
Primary source
VGNC:VGNC:104743
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
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Genomic context

See PARD6A in Genome Data Viewer
Location:
chromosome: 20
Exon count:
3
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 20 NC_041773.1 (54856947..54858797)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 20 NC_027912.1 (51996287..51998388)

Chromosome 20 - NC_041773.1Genomic Context describing neighboring genes Neighboring gene CCCTC-binding factor Neighboring gene capping protein regulator and myosin 1 linker 2 Neighboring gene chromosome 20 C16orf86 homolog Neighboring gene ACD shelterin complex subunit and telomerase recruitment factor Neighboring gene enkurin domain containing 1 Neighboring gene Gfo/Idh/MocA-like oxidoreductase domain containing 2

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein kinase C binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in centrosome cycle IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in establishment or maintenance of cell polarity IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in regulation of cellular localization IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in apical plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in cell cortex IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
partitioning defective 6 homolog alpha
Names
par-6 partitioning defective 6 homolog alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001266564.2NP_001253493.1  partitioning defective 6 homolog alpha

    See identical proteins and their annotated locations for NP_001253493.1

    Status: PROVISIONAL

    Source sequence(s)
    JV667407
    UniProtKB/TrEMBL
    G7NQ63, I2CYN5
    Conserved Domains (2) summary
    cd06403
    Location:1695
    PB1_Par6; The PB1 domain is an essential part of Par6 protein which in complex with Par3 and aPKC proteins is crucial for establishment of apical-basal polarity of animal cells. The PB1 domain is a modular domain mediating specific protein-protein interactions ...
    cd00992
    Location:156247
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041773.1 Reference Mmul_10 Primary Assembly

    Range
    54856947..54858797
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015126410.2XP_014981896.2  partitioning defective 6 homolog alpha isoform X1

    UniProtKB/TrEMBL
    G7NQ63
    Conserved Domains (2) summary
    cd06403
    Location:1695
    PB1_Par6; The PB1 domain is an essential part of Par6 protein which in complex with Par3 and aPKC proteins is crucial for establishment of apical-basal polarity of animal cells. The PB1 domain is a modular domain mediating specific protein-protein interactions ...
    cd00992
    Location:155246
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...