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MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 699331, updated on 17-Aug-2024

Summary

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Official Symbol
MAP4K2provided by VGNC
Official Full Name
mitogen-activated protein kinase kinase kinase kinase 2provided by VGNC
Primary source
VGNC:VGNC:81465
See related
Ensembl:ENSMMUG00000030597
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See MAP4K2 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
32
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (9735733..9752717)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (9660776..9677882)

Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene CDC42 binding protein kinase gamma Neighboring gene menin 1 Neighboring gene uncharacterized LOC106993199 Neighboring gene splicing factor 1 Neighboring gene glycogen phosphorylase, muscle associated

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables MAP kinase kinase kinase kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
mitogen-activated protein kinase kinase kinase kinase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041767.1 Reference Mmul_10 Primary Assembly

    Range
    9735733..9752717
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015113852.2 → XP_014969338.1  mitogen-activated protein kinase kinase kinase kinase 2 isoform X3

    UniProtKB/TrEMBL
    H9H530
    Conserved Domains (2) summary
    smart00036
    Location:488 → 773
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06613
    Location:16 → 272
    STKc_MAP4K3_like; Catalytic domain of Mitogen-activated protein kinase kinase kinase kinase (MAP4K) 3-like Serine/Threonine Kinases

  2. XM_015113850.2 → XP_014969336.1  mitogen-activated protein kinase kinase kinase kinase 2 isoform X1

    UniProtKB/TrEMBL
    H9ETH7, H9H530
    Related
    ENSMMUP00000051308.1, ENSMMUT00000073865.2
    Conserved Domains (3) summary
    smart00036
    Location:488 → 800
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    smart00220
    Location:16 → 272
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd06613
    Location:16 → 272
    STKc_MAP4K3_like; Catalytic domain of Mitogen-activated protein kinase kinase kinase kinase (MAP4K) 3-like Serine/Threonine Kinases

  3. XM_015113851.2 → XP_014969337.1  mitogen-activated protein kinase kinase kinase kinase 2 isoform X2

    UniProtKB/TrEMBL
    H9H530
    Conserved Domains (3) summary
    smart00036
    Location:480 → 792
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    smart00220
    Location:16 → 272
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd06613
    Location:16 → 272
    STKc_MAP4K3_like; Catalytic domain of Mitogen-activated protein kinase kinase kinase kinase (MAP4K) 3-like Serine/Threonine Kinases
Nucleotide Protein
Heading Accession and Version

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