TNKS tankyrase [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: TNKSprovided by VGNC
Official Full Name: tankyraseprovided by VGNC
Primary source: VGNC:VGNC:78601
Locus tag: EGK_18700
See related: Ensembl:ENSMMUG00000000965
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 8

Exon count:: 27

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	8	NC_041761.1 (10786991..11011350, complement)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	8	NC_027900.1 (10029702..10297465, complement)

Chromosome 8 - NC_041761.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

SHGC-24414 (e-PCR)
- UniSTS:81158

RH11883 (e-PCR)
- UniSTS:25352

G59681 (e-PCR)
- UniSTS:136835

RH120367 (e-PCR)
- UniSTS:132508

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables NAD+-protein poly-ADP-ribosyltransferase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: poly [ADP-ribose] polymerase tankyrase-1

Names: Tankyrase-1

NP_001248210.1

EC 2.4.2.30

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001261281.1 → NP_001248210.1 poly [ADP-ribose] polymerase tankyrase-1

See identical proteins and their annotated locations for NP_001248210.1

Status: PROVISIONAL

Source sequence(s)

JU320126

UniProtKB/TrEMBL

A0A1D5RCD4, A0A8J8XKK4, F6QQJ9, G7N0J0

Related

ENSMMUP00000001295.2, ENSMMUT00000001377.4

Conserved Domains (6) summary

PTZ00322
Location:177 → 269

PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional

PHA02876
Location:231 → 616

PHA02876; ankyrin repeat protein; Provisional

cd09524
Location:1024 → 1089

SAM_tankyrase1,2; SAM domain of tankyrase1,2 subfamily

PHA03095
Location:652 → 976

PHA03095; ankyrin-like protein; Provisional

cd01438
Location:1091 → 1313

tankyrase_like; Tankyrases interact with the telomere reverse transcriptase complex (TERT). Tankyrase 1 poly-ADP-ribosylates Telomere Repeat Binding Factor 1 (TRF1) while Tankyrase 2 can poly-ADP-ribosylate itself or TRF1. The tankyrases also contain multiple ankyrin ...

sd00045
Location:371 → 399

ANK; ANK repeat [structural motif]