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HRAS HRas proto-oncogene, GTPase [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 698830, updated on 17-Aug-2024

Summary

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Official Symbol
HRASprovided by VGNC
Official Full Name
HRas proto-oncogene, GTPaseprovided by VGNC
Primary source
VGNC:VGNC:73519
Locus tag
EGK_05817
See related
Ensembl:ENSMMUG00000021659
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See HRAS in Genome Data Viewer
Location:
chromosome: 14
Exon count:
8
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (586076..589471, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (374543..377905, complement)

Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene phosphatidylserine synthase 2 Neighboring gene ribonuclease inhibitor Neighboring gene uncharacterized LOC106993152 Neighboring gene leucine rich repeat containing 56 Neighboring gene lamin tail domain containing 2 Neighboring gene Ras association domain family member 7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GDP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Ras protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular senescence IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
GTPase HRas
Names
Transforming protein p21
v-Ha-ras Harvey rat sarcoma viral oncogene homolog
NP_001253350.1
XP_014968664.1
XP_028688383.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001266421.1 → NP_001253350.1  GTPase HRas

    See identical proteins and their annotated locations for NP_001253350.1

    Status: PROVISIONAL

    Source sequence(s)
    JU473732
    UniProtKB/TrEMBL
    A0A8J8XJP0, F7F5K9, G7NBC9
    Related
    ENSMMUP00000028522.1, ENSMMUT00000030480.3
    Conserved Domains (1) summary
    cd04138
    Location:3 → 164
    H_N_K_Ras_like; Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041767.1 Reference Mmul_10 Primary Assembly

    Range
    586076..589471 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015113178.2 → XP_014968664.1  GTPase HRas isoform X2

    UniProtKB/TrEMBL
    F7F5J9
    Related
    ENSMMUP00000028523.1, ENSMMUT00000030481.3
    Conserved Domains (1) summary
    cd04138
    Location:3 → 150
    H_N_K_Ras_like; Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B

  2. XM_028832550.1 → XP_028688383.1  GTPase HRas isoform X1

    UniProtKB/TrEMBL
    A0A8J8XJP0, F7F5K9, G7NBC9
    Conserved Domains (1) summary
    cd04138
    Location:3 → 164
    H_N_K_Ras_like; Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B

RNA

  1. XR_001439298.2 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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