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PDK4 pyruvate dehydrogenase kinase 4 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 698726, updated on 17-Aug-2024

Summary

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Official Symbol
PDK4provided by VGNC
Official Full Name
pyruvate dehydrogenase kinase 4provided by VGNC
Primary source
VGNC:VGNC:75935
Locus tag
EGK_13919
See related
Ensembl:ENSMMUG00000021389
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See PDK4 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
11
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (110533912..110546095)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (120938199..120949760, complement)

Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene dynein cytoplasmic 1 intermediate chain 1 Neighboring gene uncharacterized LOC106997564 Neighboring gene ankyrin repeat and SOCS box containing 4 Neighboring gene paraoxonase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables pyruvate dehydrogenase (acetyl-transferring) kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of glucose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial; pyruvate dehydrogenase kinase, isozyme 4
XP_001093471.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041756.1 Reference Mmul_10 Primary Assembly

    Range
    110533912..110546095
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001093471.4 → XP_001093471.1  pyruvate dehydrogenase kinase, isozyme 4

    See identical proteins and their annotated locations for XP_001093471.1

    UniProtKB/TrEMBL
    A0A8J8XI95, F7FDH5, G7MLU6, H9F8D5
    Related
    ENSMMUP00000028178.2, ENSMMUT00000030108.4
    Conserved Domains (3) summary
    smart00387
    Location:245 → 365
    HATPase_c; Histidine kinase-like ATPases
    COG0642
    Location:235 → 373
    BaeS; Signal transduction histidine kinase [Signal transduction mechanisms]
    pfam10436
    Location:34 → 195
    BCDHK_Adom3; Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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