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HIC2 HIC ZBTB transcriptional repressor 2 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 698399, updated on 17-Aug-2024

Summary

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Official Symbol
HIC2provided by VGNC
Official Full Name
HIC ZBTB transcriptional repressor 2provided by VGNC
Primary source
VGNC:VGNC:82156
Locus tag
EGK_02826
See related
Ensembl:ENSMMUG00000031089
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See HIC2 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
3
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (31426972..31462945)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 10 NC_027902.1 (62968773..62978213, complement)

Chromosome 10 - NC_041763.1Genomic Context describing neighboring genes Neighboring gene small Cajal body-specific RNA 18 Neighboring gene small Cajal body-specific RNA 17 Neighboring gene transmembrane protein 191C Neighboring gene phosphatidylinositol 4-kinase alpha Neighboring gene serpin family D member 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hypermethylated in cancer 2 protein
Names
hypermethylated in cancer 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041763.1 Reference Mmul_10 Primary Assembly

    Range
    31426972..31462945
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028827944.1 → XP_028683777.1  hypermethylated in cancer 2 protein

    UniProtKB/TrEMBL
    F6QHD8, G7N3B8
    Related
    ENSMMUP00000037246.3, ENSMMUT00000044232.3
    Conserved Domains (4) summary
    sd00017
    Location:535 → 555
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:533 → 555
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:575 → 600
    zf-H2C2_2; Zinc-finger double domain
    cd18334
    Location:25 → 144
    BTB_POZ_ZBTB30_HIC2; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in hypermethylated in cancer 2 protein (Hic-2)
Nucleotide Protein
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Molecular Biology Databases
Research Materials