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TOP3B DNA topoisomerase III beta [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 698317, updated on 17-Aug-2024

Summary

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Official Symbol
TOP3Bprovided by VGNC
Official Full Name
DNA topoisomerase III betaprovided by VGNC
Primary source
VGNC:VGNC:78623
See related
Ensembl:ENSMMUG00000014487
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See TOP3B in Genome Data Viewer
Location:
chromosome: 10
Exon count:
19
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (30960135..30986687)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 10 NC_027902.1 (63465499..63492101, complement)

Chromosome 10 - NC_041763.1Genomic Context describing neighboring genes Neighboring gene V-set pre-B cell surrogate light chain 1 Neighboring gene PRAME family member 20-like Neighboring gene protein phosphatase, Mg2+/Mn2+ dependent 1F Neighboring gene uncharacterized LOC107000564

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA topoisomerase type I (single strand cut, ATP-independent) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA topological change IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA topoisomerase 3-beta-1
Names
topoisomerase (DNA) III beta
NP_001253336.1
XP_015005238.1
XP_015005239.1
XP_015005240.1
XP_028683038.1
XP_028683039.1
XP_028683040.1
XP_028683041.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001266407.2 → NP_001253336.1  DNA topoisomerase 3-beta-1

    See identical proteins and their annotated locations for NP_001253336.1

    Status: PROVISIONAL

    Source sequence(s)
    JU472433
    UniProtKB/TrEMBL
    H9EST7, H9YZX1
    Related
    ENSMMUP00000064923.1, ENSMMUT00000101847.1
    Conserved Domains (2) summary
    cd03362
    Location:3 → 167
    TOPRIM_TopoIA_TopoIII; The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving one strand of the DNA ...
    pfam01131
    Location:169 → 582
    Topoisom_bac; DNA topoisomerase

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041763.1 Reference Mmul_10 Primary Assembly

    Range
    30960135..30986687
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028827205.1 → XP_028683038.1  DNA topoisomerase 3-beta-1 isoform X1

    UniProtKB/TrEMBL
    H9EST7, H9YZX1
    Conserved Domains (2) summary
    cd03362
    Location:3 → 167
    TOPRIM_TopoIA_TopoIII; The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving one strand of the DNA ...
    pfam01131
    Location:169 → 582
    Topoisom_bac; DNA topoisomerase

  2. XM_015149754.2 → XP_015005240.1  DNA topoisomerase 3-beta-1 isoform X4

    UniProtKB/TrEMBL
    H9EST7
    Conserved Domains (1) summary
    pfam01131
    Location:33 → 446
    Topoisom_bac; DNA topoisomerase

  3. XM_015149752.2 → XP_015005238.1  DNA topoisomerase 3-beta-1 isoform X1

    UniProtKB/TrEMBL
    H9EST7, H9YZX1
    Related
    ENSMMUP00000066861.1, ENSMMUT00000100114.1
    Conserved Domains (2) summary
    cd03362
    Location:3 → 167
    TOPRIM_TopoIA_TopoIII; The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving one strand of the DNA ...
    pfam01131
    Location:169 → 582
    Topoisom_bac; DNA topoisomerase

  4. XM_028827207.1 → XP_028683040.1  DNA topoisomerase 3-beta-1 isoform X2

    UniProtKB/TrEMBL
    A0A5F7ZRN7, G8F1W3, H9EST7
    Related
    ENSMMUP00000068308.1, ENSMMUT00000106258.1
    Conserved Domains (2) summary
    cd03362
    Location:3 → 167
    TOPRIM_TopoIA_TopoIII; The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving one strand of the DNA ...
    pfam01131
    Location:169 → 533
    Topoisom_bac; DNA topoisomerase

  5. XM_015149753.2 → XP_015005239.1  DNA topoisomerase 3-beta-1 isoform X3

    UniProtKB/TrEMBL
    H9EST7
    Conserved Domains (2) summary
    cd03362
    Location:8 → 106
    TOPRIM_TopoIA_TopoIII; The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving one strand of the DNA ...
    pfam01131
    Location:108 → 521
    Topoisom_bac; DNA topoisomerase

  6. XM_028827206.1 → XP_028683039.1  DNA topoisomerase 3-beta-1 isoform X1

    UniProtKB/TrEMBL
    H9EST7, H9YZX1
    Conserved Domains (2) summary
    cd03362
    Location:3 → 167
    TOPRIM_TopoIA_TopoIII; The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving one strand of the DNA ...
    pfam01131
    Location:169 → 582
    Topoisom_bac; DNA topoisomerase

  7. XM_028827208.1 → XP_028683041.1  DNA topoisomerase 3-beta-1 isoform X4

    UniProtKB/TrEMBL
    H9EST7
    Conserved Domains (1) summary
    pfam01131
    Location:33 → 446
    Topoisom_bac; DNA topoisomerase
Nucleotide Protein
Heading Accession and Version

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